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In molecular dynamics (MD), systems are molecules made up of atoms, and the aim is to determine their evolution over time. MD is based on a numerical resolution algorithm, whose role is to apply the forces generated by the various…

Statistical Mechanics · Physics 2024-10-16 Frédéric Boussinot

Molecular dynamics simulations have emerged as a potent tool for investigating the physical properties and kinetic behaviors of materials at the atomic scale, particularly in extreme conditions. Ab initio accuracy is now achievable with…

We introduce JAX MD, a software package for performing differentiable physics simulations with a focus on molecular dynamics. JAX MD includes a number of physics simulation environments, as well as interaction potentials and neural networks…

Computational Physics · Physics 2020-12-04 Samuel S. Schoenholz , Ekin D. Cubuk

Large video diffusion and flow models have achieved remarkable success in high-quality video generation, but their use in real-time interactive applications remains limited due to their inefficient multi-step sampling process. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Weili Nie , Julius Berner , Nanye Ma , Chao Liu , Saining Xie , Arash Vahdat

The simulation of high-energy physics collision events is a key element for data analysis at present and future particle accelerators. The comparison of simulation predictions to data allows looking for rare deviations that can be due to…

High Energy Physics - Experiment · Physics 2024-07-16 Francesco Vaselli , Filippo Cattafesta , Patrick Asenov , Andrea Rizzi

Translational diffusion coefficients are routinely estimated from molecular dynamics simulations. Linear fits to mean squared displacement (MSD) curves have become the de facto standard, from simple liquids to complex biomacromolecules.…

Computational Physics · Physics 2020-11-20 Jakob Tómas Bullerjahn , Sören von Bülow , Gerhard Hummer

We present a hybrid continuum-atomistic scheme which combines molecular dynamics (MD) simulations with on-the-fly machine learning techniques for the accurate and efficient prediction of multiscale fluidic systems. By using a Gaussian…

Fluid Dynamics · Physics 2016-03-16 David Stephenson , James R Kermode , Duncan A Lockerby

Warm dense matter systems created in the laboratory are highly dynamical. In such cases electron dynamics is often needed to accurately simulate the evolution and properties of the system. Large systems force one to make simple…

Quantum Gases · Physics 2014-08-13 Paul E. Grabowski

For 35 years, {\it ab initio} molecular dynamics (AIMD) has been the method of choice for modeling complex atomistic phenomena from first principles. However, most AIMD applications are limited by computational cost to systems with…

Computational Physics · Physics 2020-09-15 Weile Jia , Han Wang , Mohan Chen , Denghui Lu , Lin Lin , Roberto Car , Weinan E , Linfeng Zhang

Different parallel frameworks for implementing data analysis applications have been proposed by the HPC and Big Data communities. In this paper, we investigate three task-parallel frameworks: Spark, Dask and RADICAL-Pilot with respect to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-12 Ioannis Paraskevakos , Andre Luckow , Mahzad Khoshlessan , George Chantzialexiou , Thomas E. Cheatham , Oliver Beckstein , Geoffrey C. Fox , Shantenu Jha

Computational fluid dynamics (CFD) can be used to simulate vascular haemodynamics and analyse potential treatment options. CFD has shown to be beneficial in improving patient outcomes. However, the implementation of CFD for routine clinical…

A novel approach to simulate simple protein-ligand systems at large time- and length-scales is to couple Markov state models (MSMs) of molecular kinetics with particle-based reaction-diffusion (RD) simulations, MSM/RD. Currently, MSM/RD…

Chemical Physics · Physics 2021-12-10 Mauricio J. del Razo , Manuel Dibak , Christof Schütte , Frank Noé

Simulations are vital for understanding and predicting the evolution of complex molecular systems. However, despite advances in algorithms and special purpose hardware, accessing the timescales necessary to capture the structural evolution…

Computational Physics · Physics 2021-02-18 Pantelis R. Vlachas , Julija Zavadlav , Matej Praprotnik , Petros Koumoutsakos

Molecular Dynamic (MD) approach is applied to study the converging cylindrical shock waves in a dense Lennard-Jones (LJ) fluid. MD method is based on tracking of the atom motions and hence it has an fundamental advantages over hydrodynamic…

Computational Physics · Physics 2009-04-23 V. Zhakhovskii , K. Nishihara , M. Abe

Memory-to-memory data streaming is essential for modern scientific workflows that require near real-time data analysis, experimental steering, and informed decision-making during experiment execution. It eliminates the latency bottlenecks…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-10 Anjus George , Michael J. Brim , Christopher Zimmer , Tyler J. Skluzacek , A. J. Ruckman , Gustav R. Jansen , Sarp Oral

Understanding molecular structure, dynamics, and reactivity requires bridging processes that occur across widely separated time scales. Conventional molecular dynamics simulations provide atomistic resolution, but their femtosecond time…

Chemical Physics · Physics 2025-10-10 Juan Viguera Diez , Mathias Schreiner , Simon Olsson

Molecular dynamics simulations are an important tool for describing the evolution of a chemical system with time. However, these simulations are inherently held back either by the prohibitive cost of accurate electronic structure theory…

Chemical Physics · Physics 2018-12-20 Michael Gastegger , Philipp Marquetand

We present an efficient parallel algorithm for statistical Molecular Dynamics simulations of ion tracks in solids. The method is based on the Rare Event Enhanced Domain following Molecular Dynamics (REED-MD) algorithm, which has been…

Computational Physics · Physics 2009-05-04 Byoungseon Jeon , Niels Grønbech-Jensen

This paper introduces Memory-limited Online Subspace Estimation Scheme (MOSES) for both estimating the principal components of streaming data and reducing its dimension. More specifically, in various applications such as sensor networks,…

Information Theory · Computer Science 2021-02-12 Armin Eftekhari , Raphael A. Hauser , Andreas Grammenos

Three coarse-grained molecular dynamics (MD) models are investigated with the aim of developing and analyzing multiscale methods which use MD simulations in parts of the computational domain and (less detailed) Brownian dynamics (BD)…

Computational Physics · Physics 2015-06-18 Radek Erban