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Large Language Models (LLMs) offer new opportunities to accelerate complex interdisciplinary research domains. Epidemic modeling, characterized by its complexity and reliance on network science, dynamical systems, epidemiology, and…

Social and Information Networks · Computer Science 2026-02-26 Mohammad Hossein Samaei , Faryad Darabi Sahneh , Lee W. Cohnstaedt , Caterina Scoglio

The potential of automatic task-solving through Large Language Model (LLM)-based multi-agent collaboration has recently garnered widespread attention from both the research community and industry. While utilizing natural language to…

Human-Computer Interaction · Computer Science 2024-04-19 Bo Pan , Jiaying Lu , Ke Wang , Li Zheng , Zhen Wen , Yingchaojie Feng , Minfeng Zhu , Wei Chen

Scientific innovation is pivotal for humanity, and harnessing large language models (LLMs) to generate research ideas could transform discovery. However, existing LLMs often produce simplistic and repetitive suggestions due to their limited…

Artificial Intelligence · Computer Science 2024-10-29 Xiang Hu , Hongyu Fu , Jinge Wang , Yifeng Wang , Zhikun Li , Renjun Xu , Yu Lu , Yaochu Jin , Lili Pan , Zhenzhong Lan

Large Language Models (LLMs) have revolutionized Natural Language Processing but exhibit limitations, particularly in autonomously addressing novel challenges such as reasoning and problem-solving. Traditional techniques like…

Multiagent Systems · Computer Science 2024-01-03 Sumedh Rasal

The rise of Generative AI, and Large Language Models (LLMs) in particular, is fundamentally changing cognitive processes in knowledge work, raising critical questions about their impact on human reasoning and problem-solving capabilities.…

Human-Computer Interaction · Computer Science 2025-04-04 Joshua Holstein , Moritz Diener , Philipp Spitzer

Generative AI, especially through large language models (LLMs), is transforming how technical knowledge can be accessed, reused, and extended. PETSc, a widely used numerical library for high-performance scientific computing, has accumulated…

Large language models (LLMs) are increasingly used as simulated participants in social science experiments, but their behavior is often unstable and highly sensitive to design choices. Prior evaluations frequently conflate base-model…

Artificial Intelligence · Computer Science 2026-02-03 Xuan Liu , Haoyang Shang , Zizhang Liu , Xinyan Liu , Yunze Xiao , Yiwen Tu , Haojian Jin

This paper presents a benchmark self-evolving framework to dynamically evaluate rapidly advancing Large Language Models (LLMs), aiming for a more accurate assessment of their capabilities and limitations. We utilize a multi-agent system to…

Computation and Language · Computer Science 2024-02-20 Siyuan Wang , Zhuohan Long , Zhihao Fan , Zhongyu Wei , Xuanjing Huang

Large Language Models (LLMs) can be seen as compressed knowledge bases, but it remains unclear what knowledge they truly contain and how far their knowledge boundary extends. Existing benchmarks are mostly static and provide limited support…

Machine Learning · Computer Science 2026-05-27 Yuheng Yang , Siqi Zhu , Tao Feng , Ge Liu , Jiaxuan You

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

Large language models (LLMs) have demonstrated exceptional potential in complex reasoning,pioneering a new paradigm for autonomous agent decision making in dynamic settings. However, in Real-Time Strategy (RTS) scenarios, LLMs suffer from a…

Multiagent Systems · Computer Science 2026-03-26 Li Ma , Hao Peng , Yiming Wang , Hongbin Luo , Jie Liu , Kongjing Gu , Guanlin Wu , Hui Lin , Lei Ren

We present BioLunar, developed using the Lunar framework, as a tool for supporting biological analyses, with a particular emphasis on molecular-level evidence enrichment for biomarker discovery in oncology. The platform integrates Large…

Deep research agents powered by Large Language Models (LLMs) can perform multi-step reasoning, web exploration, and long-form report generation. However, most existing systems operate in an autonomous manner, assuming fully specified user…

Computation and Language · Computer Science 2026-01-13 Yingchaojie Feng , Qiang Huang , Xiaoya Xie , Zhaorui Yang , Jun Yu , Wei Chen , Anthony K. H. Tung

Recent advances in AI agents for software engineering and scientific discovery have demonstrated remarkable capabilities, yet their application to developing novel ranking models in commercial search engines remains unexplored. In this…

Information Retrieval · Computer Science 2026-03-25 Liwei Wu , Cho-Jui Hsieh

Identifying novel hypotheses is essential to scientific research, yet this process risks being overwhelmed by the sheer volume and complexity of available information. Existing automated methods often struggle to generate novel and…

We introduce Evolutionary Ensemble (EvE), a decentralized framework that organizes existing, highly capable coding agents into a live, co-evolving system for algorithmic discovery. Rather than reinventing the wheel within the "LLMs as…

Neural and Evolutionary Computing · Computer Science 2026-05-15 Zongmin Yu , Liu Yang

Collaboration is the defining mode of modern science, yet its core mechanism -- feedback -- remains hard to observe, difficult to scale, and unequally distributed. Here we test whether large language models (LLMs) can contribute to this…

Physics and Society · Physics 2026-05-26 Binglu Wang , Weixin Liang , Jiahui Xue , Yuhui Zhang , Hancheng Cao , Dashun Wang , Yian Yin

The powerful reasoning capabilities of Large Language Models (LLMs) in mathematics and coding, combined with their ability to automate complex tasks through agentic frameworks, present unprecedented opportunities for accelerating scientific…

Artificial Intelligence · Computer Science 2025-05-27 Jiabin Tang , Lianghao Xia , Zhonghang Li , Chao Huang

The emergence of Large Language Model (LLM) agents enables us to build agent-based intelligent systems that move beyond the role of a "tool" to become genuine collaborators with humans, thereby realizing a novel human-agent collaboration…

Human-Computer Interaction · Computer Science 2026-02-06 Bingsheng Yao , Chaoran Chen , April Yi Wang , Sherry Tongshuang Wu , Toby Jia-jun Li , Dakuo Wang

Scientific discovery still relies heavily on the manual efforts of individual researchers, leading to limited exploration, redundant trials, and reduced reproducibility. Human-participant data analysis competitions generate diverse…

Multiagent Systems · Computer Science 2026-03-05 Satoshi Oyama , Yuko Sakurai , Hisashi Kashima
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