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Identifying novel hypotheses is essential to scientific research, yet this process risks being overwhelmed by the sheer volume and complexity of available information. Existing automated methods often struggle to generate novel and…

Hypothesis generation is a fundamental step in scientific discovery, yet it is increasingly challenged by information overload and disciplinary fragmentation. Recent advances in Large Language Models (LLMs) have sparked growing interest in…

The exponential growth of scientific knowledge has made the automated generation of scientific hypotheses that combine novelty, feasibility, and research value a core challenge. Existing methods based on large language models fail to…

Artificial Intelligence · Computer Science 2025-08-05 Shiyang Duan , Yuan Tian , Qi Bing , Xiaowei Shao

AI holds promise for transforming scientific processes, including hypothesis generation. Prior work on hypothesis generation can be broadly categorized into theory-driven and data-driven approaches. While both have proven effective in…

Artificial Intelligence · Computer Science 2025-01-10 Haokun Liu , Yangqiaoyu Zhou , Mingxuan Li , Chenfei Yuan , Chenhao Tan

Nowadays, single Large Language Model (LLM) struggles with critical issues such as hallucination and inadequate reasoning abilities. To mitigate these issues, Multi-Agent Debate (MAD) has emerged as an effective strategy, where LLM agents…

Artificial Intelligence · Computer Science 2025-07-08 Yiliu Sun , Zicheng Zhao , Sheng Wan , Chen Gong

Multi-agent debate system (MAD) imitating the process of human discussion in pursuit of truth, aims to align the correct cognition of different agents for the optimal solution. It is challenging to make various agents perform right and…

Computation and Language · Computer Science 2024-07-12 Haotian Wang , Xiyuan Du , Weijiang Yu , Qianglong Chen , Kun Zhu , Zheng Chu , Lian Yan , Yi Guan

Accurate diagnosis of Mendelian diseases is crucial for precision therapy and assistance in preimplantation genetic diagnosis. However, existing methods often fall short of clinical standards or depend on extensive datasets to build…

When human operators of cyber-physical systems encounter surprising behavior, they often consider multiple hypotheses that might explain it. In some cases, taking information-gathering actions such as additional measurements or control…

Artificial Intelligence · Computer Science 2024-11-22 Ofer Dagan , Tyler Becker , Zachary N. Sunberg

Contemporary approaches to assisted scientific discovery use language models to automatically generate large numbers of potential hypothesis to test, while also automatically generating code-based experiments to test those hypotheses. While…

Artificial Intelligence · Computer Science 2025-09-23 Peter Jansen , Samiah Hassan , Ruoyao Wang

Incorporating personas information allows diverse and engaging responses in dialogue response generation. Unfortunately, prior works have primarily focused on self personas and have overlooked the value of partner personas. Moreover, in…

Computation and Language · Computer Science 2021-11-30 Hongyuan Lu , Wai Lam , Hong Cheng , Helen M. Meng

Significant scientific discoveries have driven the progress of human civilisation. The explosion of scientific literature and data has created information barriers across disciplines that have slowed the pace of scientific discovery. Large…

Computation and Language · Computer Science 2023-11-13 Biqing Qi , Kaiyan Zhang , Haoxiang Li , Kai Tian , Sihang Zeng , Zhang-Ren Chen , Bowen Zhou

Multimodal multihop question answering (MMQA) requires reasoning over images and text from multiple sources. Despite advances in visual question answering, this multihop setting remains underexplored due to a lack of quality datasets.…

Computation and Language · Computer Science 2025-09-16 Amirhossein Abaskohi , Spandana Gella , Giuseppe Carenini , Issam H. Laradji

Multi-agent systems have emerged as a powerful paradigm for automating scientific discovery. To differentiate agent behavior in the multi-agent system, current frameworks typically assign generic role-based personas such as ''reviewer'' or…

Artificial Intelligence · Computer Science 2026-02-03 Yunhui Jang , Seonghyun Park , Jaehyung Kim , Sungsoo Ahn

Large language models (LLMs) have demonstrated remarkable capabilities in language generation, understanding, and few-shot learning in recent years. An extensive body of work has explored how their performance may be further improved…

Computation and Language · Computer Science 2023-05-24 Yilun Du , Shuang Li , Antonio Torralba , Joshua B. Tenenbaum , Igor Mordatch

Writing persuasive arguments is a challenging task for both humans and machines. It entails incorporating high-level beliefs from various perspectives on the topic, along with deliberate reasoning and planning to construct a coherent…

Computation and Language · Computer Science 2025-01-06 Zhe Hu , Hou Pong Chan , Jing Li , Yu Yin

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

Generating novel and creative scientific hypotheses is a cornerstone in achieving Artificial General Intelligence. Large language and reasoning models have the potential to aid in the systematic creation, selection, and validation of…

Computation and Language · Computer Science 2025-04-18 Charles O'Neill , Tirthankar Ghosal , Roberta Răileanu , Mike Walmsley , Thang Bui , Kevin Schawinski , Ioana Ciucă

Automatically generating debates is a challenging task that requires an understanding of arguments and how to negate or support them. In this work we define debate trees and paths for generating debates while enforcing a high level…

Computation and Language · Computer Science 2020-12-02 Eric Bolton , Alex Calderwood , Niles Christensen , Jerome Kafrouni , Iddo Drori

As an agent-level reasoning and coordination paradigm, Multi-Agent Debate (MAD) orchestrates multiple agents through structured debate to improve answer quality and support complex reasoning. However, existing research on MAD suffers from…

Artificial Intelligence · Computer Science 2026-01-07 Ao Li , Jinghui Zhang , Luyu Li , Yuxiang Duan , Lang Gao , Mingcai Chen , Weijun Qin , Shaopeng Li , Fengxian Ji , Ning Liu , Lizhen Cui , Xiuying Chen , Yuntao Du

Spoken dialogue generation is crucial for applications like podcasts, dynamic commentary, and entertainment content, but poses significant challenges compared to single-utterance text-to-speech (TTS). Key requirements include accurate…

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