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We investigate fully self-consistent multiscale quantum-classical algorithms on current generation superconducting quantum computers, in a unified approach to tackle the correlated electronic structure of large systems in both quantum…

Recent research has shown that wavefunction evolution in real- and imaginary-time can generate quantum subspaces with significant utility for obtaining accurate ground state energies. Inspired by these methods, we propose combining quantum…

Hybrid quantum-classical algorithms provide ways to use noisy intermediate-scale quantum computers for practical applications. Expanding the portfolio of such techniques, we propose a quantum circuit learning algorithm that can be used to…

Quantum computing offers fundamentally more expressive mechanisms for generative modeling, yet current approaches remain constrained by classical neural components that bottleneck quantum capability and hardware efficiency. We propose the…

Quantum Physics · Physics 2025-10-06 Yihua Li , Jiayi Chen , Tamanna S. Kumavat , Kyriakos Flouris

The feasibility of variational quantum algorithms, the most popular correspondent of neural networks on noisy, near-term quantum hardware, is highly impacted by the circuit depth of the involved parametrized quantum circuits (PQCs). Higher…

Machine Learning · Computer Science 2024-11-01 Philipp Schleich , Marta Skreta , Lasse B. Kristensen , Rodrigo A. Vargas-Hernández , Alán Aspuru-Guzik

Quantum Machine Learning algorithms based on Variational Quantum Circuits (VQCs) are important candidates for useful application of quantum computing. It is known that a VQC is a linear model in a feature space determined by its…

Quantum Physics · Physics 2025-07-09 Slimane Thabet , Léo Monbroussou , Eliott Z. Mamon , Jonas Landman

Hybrid quantum-classical approaches offer potential solutions to quantum chemistry problems, yet they often manifest as constrained optimization problems. Here, we explore the interconnection between constrained optimization and generalized…

Quantum Physics · Physics 2025-03-27 Muqing Zheng , Bo Peng , Ang Li , Xiu Yang , Karol Kowalski

Magnetic resonance imaging (MRI) is a common technique to scan brains for strokes, tumors, and other abnormalities that cause forms of dementia. However, correctly diagnosing forms of dementia from MRIs is difficult, as nearly 1 in 3…

Quantum Physics · Physics 2023-05-16 Ryan Kim

As the quantum computing community gravitates towards understanding the practical benefits of quantum computers, having a clear definition and evaluation scheme for assessing practical quantum advantage in the context of specific…

Machine Learning · Computer Science 2023-05-12 Kaitlin Gili , Marta Mauri , Alejandro Perdomo-Ortiz

Quantum generative models offer a novel approach to exploring high-dimensional Hilbert spaces but face significant challenges in scalability and expressibility when applied to multi-modal distributions. In this study, we explore a Hybrid…

Quantum Physics · Physics 2026-02-06 Jeongbin Jo , Santanam Wishal , Shah Md Khalil Ullah , Shan Zeng , Dikshant Dulal

There is no unique way to encode a quantum algorithm into a quantum circuit. With limited qubit counts, connectivities, and coherence times, circuit optimization is essential to make the best use of near-term quantum devices. We introduce…

Photonic quantum computing has gained significant interest in recent years due to its potential for scaling to large numbers of qubits. A critical requirement for fault-tolerant quantum computation is the reliable generation of non-Gaussian…

Quantum Physics · Physics 2026-03-20 S. Ismailzadeh , B. Abedi Ravan

A central challenge in quantum machine learning is the design and training of parameterized quantum circuits (PQCs). Similar to deep learning, vanishing gradients pose immense problems in the trainability of PQCs, which have been shown to…

We propose a variational framework for solving ground-state problems of open quantum systems governed by quantum stochastic differential equations (QSDEs). This formulation naturally accommodates bosonic operators, as commonly encountered…

Quantum Physics · Physics 2025-12-17 Yunyan Lee , Ian R. Petersen , Daoyi Dong

We investigate variational learning of quantum many-body ground states directly in measurement space using autoregressive neural networks. In particular, we represent quantum states via probability distributions of outcomes over a symmetric…

Quantum Physics · Physics 2026-05-29 Kartiek Agarwal

In the Noisy Intermediate-Scale Quantum (NISQ) era, using variational quantum algorithms (VQAs) to solve optimization problems has become a key application. However, these algorithms face significant challenges, such as choosing an…

Quantum Physics · Physics 2025-06-13 Junyong Lee , JeiHee Cho , Shiho Kim

We explore the effectiveness of variational quantum circuits in simulating the ground states of quantum many-body Hamiltonians. We show that generic high-depth circuits, performing a sequence of layer unitaries of the same form, can…

Quantum Physics · Physics 2021-06-16 Joonho Kim , Jaedeok Kim , Dario Rosa

The design of parametric quantum circuits (PQCs) for efficient use in variational quantum simulations (VQS) is subject to two competing factors. On one hand, the set of states that can be generated by the PQC has to be large enough to…

Quantum Physics · Physics 2026-03-13 Lena Funcke , Tobias Hartung , Karl Jansen , Stefan Kühn , Manuel Schneider , Paolo Stornati

Given (small amounts of) time-series' data from a high-dimensional, fine-grained, multiscale dynamical system, we propose a generative framework for learning an effective, lower-dimensional, coarse-grained dynamical model that is predictive…

Machine Learning · Statistics 2021-01-18 Sebastian Kaltenbach , Phaedon-Stelios Koutsourelakis

Quantum computing promises to efficiently and accurately solve many important problems in quantum chemistry which elude classical solvers, such as the electronic structure problem of highly correlated materials. Two leading methods in…

Quantum Physics · Physics 2025-12-17 Sean Thrasher , Ioannis Kolotouros , Julien Michel , Petros Wallden
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