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The field of AI research is advancing at an unprecedented pace, enabling automated hypothesis generation and experimental design across diverse domains such as biology, mathematics, and artificial intelligence. Despite these advancements,…

Machine Learning · Computer Science 2025-10-07 Yaowenqi Liu , Bingxu Meng , Rui Pan , Yuxing Liu , Jerry Huang , Jiaxuan You , Tong Zhang

The complexity of psychological principles underscore a significant societal challenge, given the vast social implications of psychological problems. Bridging the gap between understanding these principles and their actual clinical and…

Artificial Intelligence · Computer Science 2023-12-11 Tianyu He , Guanghui Fu , Yijing Yu , Fan Wang , Jianqiang Li , Qing Zhao , Changwei Song , Hongzhi Qi , Dan Luo , Huijing Zou , Bing Xiang Yang

Drug addiction is a complex and pervasive global challenge that continues to pose significant public health concerns. Traditional approaches to anti-addiction drug discovery have struggled to deliver effective therapeutics, facing high…

Biomolecules · Quantitative Biology 2025-02-11 Dong Chen , Jian Jiang , Zhe Su , Guo-Wei Wei

Assuring safety of artificial intelligence (AI) applied to safety-critical systems is of paramount importance. Especially since research in the field of automated driving shows that AI is able to outperform classical approaches, to handle…

Computers and Society · Computer Science 2025-04-28 Lars Ullrich , Michael Buchholz , Klaus Dietmayer , Knut Graichen

The use of artificial intelligence (AI) in healthcare has become a very active research area in the last few years. While significant progress has been made in image classification tasks, only a few AI methods are actually being deployed in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Ramon Correa , Jiwoong Jason Jeong , Bhavik Patel , Hari Trivedi , Judy W. Gichoya , Imon Banerjee

Artificial intelligence has provided us with an exploration of a whole new research era. As more data and better computational power become available, the approach is being implemented in various fields. The demand for it in health…

Machine Learning · Computer Science 2020-08-11 Gloria Hyunjung Kwak , Pan Hui

Artificial intelligence (AI) has been successfully applied in numerous scientific domains. In biomedicine, AI has already shown tremendous potential, e.g. in the interpretation of next-generation sequencing data and in the design of…

Modern studies increasingly leverage outcomes predicted by machine learning and artificial intelligence (AI/ML) models, and recent work, such as prediction-powered inference (PPI), has developed valid downstream statistical inference…

Methodology · Statistics 2026-03-18 Yiqun T. Chen , Moran Guo , Shengy Li

The energy consumption and carbon footprint of Artificial Intelligence (AI) have become critical concerns due to rising costs and environmental impacts. In response, a new trend in green AI is emerging, shifting from the "bigger is better"…

Computers and Society · Computer Science 2025-10-03 Tiago da Silva Barros , Frédéric Giroire , Ramon Aparicio-Pardo , Joanna Moulierac

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

Artificial intelligence (AI) raises expectations of substantial increases in rates of technological and scientific progress, but such anticipations are often not connected to detailed ground-level studies of AI use in innovation processes.…

Computers and Society · Computer Science 2025-11-21 John P. Nelson , Olajide Olugbade , Philip Shapira , Justin B. Biddle

Recent advances in artificial intelligence applied to biomedical text are opening exciting opportunities for improving pharmacovigilance activities currently burdened by the ever growing volumes of real world data. To fully realize these…

Information Retrieval · Computer Science 2022-01-04 Bruno Ohana , Jack Sullivan , Nicole Baker

With the growing reliance on artificial intelligence (AI) for many different applications, the sharing of code, data, and models is important to ensure the replicability and democratization of scientific knowledge. Many high-profile…

Computers and Society · Computer Science 2022-10-24 Danish Contractor , Daniel McDuff , Julia Haines , Jenny Lee , Christopher Hines , Brent Hecht , Nicholas Vincent , Hanlin Li

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot…

Machine Learning · Computer Science 2019-03-25 Jack Albright

Recently, a lot of attention has been given to undesired consequences of Artificial Intelligence (AI), such as unfair bias leading to discrimination, or the lack of explanations of the results of AI systems. There are several important…

Computers and Society · Computer Science 2019-12-23 Richard Benjamins , Alberto Barbado , Daniel Sierra

Pharmaceutical three-dimensional (3D) printing is an advanced fabrication technology with the potential to enable truly personalised dosage forms. Recent studies have integrated artificial intelligence (AI) to accelerate formulation and…

Artificial Intelligence · Computer Science 2026-05-19 Adeshola Okubena , Yusuf Ali Mohammed , Moe Elbadawi

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

Over 1,200 AI-enabled medical devices have received marketing authorization from the U.S. FDA, yet identifying devices suited to specific clinical needs remains challenging because the FDA's databases contain only limited metadata and…

Information Retrieval · Computer Science 2026-02-03 Arun Kavishwar , William Lotter

In 2023, the U.S. Food and Drug Administration issued guidance for adjustment of covariates in randomized clinical trials, emphasizing its role in enhancing precision and power through prognostic baseline variables. Despite its potential,…

Methodology · Statistics 2026-05-28 Kelly Van Lancker , Iván Díaz , Stijn Vansteelandt
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