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Mid-infrared photothermal microscopy is a highly promising imaging technique that enables spatially resolved vibrational fingerprinting. The combination of infrared induced heating with optical readout at visible wavelengths provides…

Optics · Physics 2025-08-05 Dennis van de Lockand , Daan Wolters , Matz Liebel

Label-free vibrational microscopy provides chemically specific access to cellular structure, yet quantitative volumetric chemical dynamics in living cells remain largely inaccessible, particularly on subsecond timescales relevant to…

Three-dimensional molecular imaging of living cells is essential for unraveling cellular metabolism and response to therapies. However, existing volumetric methods, including fluorescence microscopy and quantitative phase imaging, either…

Mid-infrared spectroscopy, an important and widespread technique for sensing molecules, has encountered barriers stemming from sources either limited in tuning range or excessively bulky for practical field use. We present a compact,…

Recently, computational sampling methods have been implemented to spatially characterize terahertz (THz) fields. Previous methods usually rely on either specialized THz devices such as THz spatial light modulators, or complicated systems…

Optics · Physics 2019-06-19 Jiapeng Zhao , Yiwen E , Kaia Williams , Xi-cheng Zhang , Robert Boyd

Black phosphorus stands out from the family of two-dimensional materials as a semiconductor with a direct, layer-dependent bandgap in energy corresponding to the spectral range from the visible to the mid-infrared (mid-IR), as well as many…

Optics · Physics 2017-10-10 Ruoming Peng , Kaveh Khaliji , Nathan Youngblood , Roberto Grassi , Tony Low , Mo Li

Substrate-transferred crystalline coatings have recently emerged as a groundbreaking new concept in optical interference coatings. Building upon our initial demonstration of this technology, we have now realized significant improvements in…

We propose a scheme for infrared single-photon detection based on two-photon absorption at room-temperature in Si avalanche photodiodes, where the detected photon's energy is lower than the bandgap and the energy difference is complemented…

Materials Science · Physics 2008-02-14 Alex Hayat , Pavel Ginzburg , Meir Orenstein

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

Signal Processing · Electrical Eng. & Systems 2023-07-18 Olivier Leblanc , Matthias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

The microscale integration of mid- and longwave-infrared photonics could enable the development of fieldable, robust chemical sensors, as well as highly efficient infrared frequency converters. However, such technology would be defined by…

Wide-field mid-infrared photothermal (MIP) imaging offers rapid labelfree chemical contrast for biomedical and polymer analysis. However, its field of view (FOV) is limited by the pulse intensity of conventional infrared lasers. Here, we…

Multispectral imaging (MSI) captures data across multiple spectral bands, offering enhanced informational depth compared to standard RGB imaging and benefiting diverse fields such as agriculture, medical diagnostics, and industrial…

Instrumentation and Detectors · Physics 2025-08-29 Muchen Zhu , Baolei Liu , Yao Wang , Linjun Zhai , Jiaqi Song , Nana Liu , Zhaohua Yang , Lei Ding , Fan Wang

The thin and flexible nature of optical fibres often makes them the ideal technology to view biological processes in-vivo, but current microendoscopic approaches are limited in spatial resolution. Here, we demonstrate a new route to high…

Superconducting nanowire single-photon detectors (SNSPDs) with high timing resolution and low background counts in the mid infrared (MIR) have the potential to open up numerous opportunities in fields such as exoplanet searches, direct dark…

The mid-infrared spectral window is essential for molecular fingerprinting and atmospheric sensing, yet unlocking its full potential is currently constrained by a fundamental instrumental trade-off: existing systems cannot simultaneously…

X-ray imaging is an invaluable tool for noninvasive analysis in many fields ranging from basic science to medicine and security. The development of low-dose large area imaging solutions still represents an important challenge for various…

Instrumentation and Detectors · Physics 2024-11-07 M. Simões , P. Vaz , A. F. V. Cortez

Mid-infrared spectroscopic imaging (MIRSI) is an emerging class of label-free techniques being leveraged for digital histopathology. Modern histopathologic identification of ovarian cancer involves tissue staining followed by morphological…

We report on the design of an all-mirror wavefront-division interferometer capable of spectroscopic studies across multiple spectral ranges$\unicode{x2013}$from the plasma frequencies of metals to terahertz wavelengths and beyond. The…

In most biological tissues, light scattering due to small differences in refractive index limits the depth of optical imaging systems. Two-photon microscopy (2PM), which significantly reduces the scattering of the excitation light, has…

Image inpainting has achieved fundamental advances with deep learning. However, almost all existing inpainting methods aim to process natural images, while few target Thermal Infrared (TIR) images, which have widespread applications. When…

Computer Vision and Pattern Recognition · Computer Science 2022-10-31 Zeyu Wang , Haibin Shen , Changyou Men , Quan Sun , Kejie Huang
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