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This work presents Quantum Adaptive Search (QAGS), a hybrid quantum-classical algorithm for the global optimization of multivariate functions. The method employs an adaptive mechanism that dynamically narrows the search space based on a…

Quantum Physics · Physics 2025-06-27 G. Intoccia , U. Chirico , V. Schiano Di Cola , G. Pepe , S. Cuomo

Recent advance in classical reinforcement learning (RL) and quantum computation (QC) points to a promising direction of performing RL on a quantum computer. However, potential applications in quantum RL are limited by the number of qubits…

Quantum Physics · Physics 2022-03-07 Samuel Yen-Chi Chen , Chih-Min Huang , Chia-Wei Hsing , Hsi-Sheng Goan , Ying-Jer Kao

While thousands of experimental physicists and chemists are currently trying to build scalable quantum computers, it appears that simulation of quantum computation will be at least as critical as circuit simulation in classical VLSI design.…

Quantum Physics · Physics 2007-05-23 George F. Viamontes , Manoj Rajagopalan , Igor L. Markov , John P. Hayes

Quantum Local Search (QLS) is a promising approach that employs small-scale quantum computers to tackle large combinatorial optimization problems through local search on quantum hardware, starting from an initial point. However, the random…

Quantum Physics · Physics 2023-04-14 Chen-Yu Liu , Hsi-Sheng Goan

Configuring variational quantum algorithms for combinatorial optimization remains a difficult, expert-driven process requiring coordinated choices over solver family, ansatz, objective, and optimizer. We present AutoQResearch, an LLM-guided…

Quantum Physics · Physics 2026-04-28 Monit Sharma , Hoong Chuin Lau

Variational quantum algorithms (VQAs) have been successfully applied to quantum approximate optimization algorithms, variational quantum compiling and quantum machine learning models. The performances of VQAs largely depend on the…

Quantum Physics · Physics 2022-09-14 Zhimin He , Chuangtao Chen , Lvzhou Li , Shenggen Zheng , Haozhen Situ

Simulating Clifford and near-Clifford circuits using the extended stabilizer formalism has become increasingly popular, particularly in quantum error correction. Compared to the state-vector approach, the extended stabilizer formalism can…

Quantum Physics · Physics 2026-05-18 Vu Tuan Hai , Bui Cao Doanh , Le Vu Trung Duong , Pham Hoai Luan , Yasuhiko Nakashima

We propose a variational quantum eigensolver (VQE) algorithm that uses a fault-tolerant gate-set, and is hence suitable for implementation on a future error-corrected quantum computer. VQE quantum circuits are typically designed for…

Quantum Physics · Physics 2023-03-09 Hasan Sayginel , Francois Jamet , Abhishek Agarwal , Dan E. Browne , Ivan Rungger

We propose a method for constructing $\texttt{PREPARE}$ circuits for quantum phase estimation of a molecular Hamiltonian in quantum chemistry by using variational optimization of quantum circuits solely on classical computers. The…

Quantum Physics · Physics 2025-05-02 Hayata Morisaki , Kosuke Mitarai , Keisuke Fujii , Yuya O. Nakagawa

Quantum computing offers efficient encapsulation of high-dimensional states. In this work, we propose a novel quantum reinforcement learning approach that combines the Advantage Actor-Critic algorithm with variational quantum circuits by…

We provide a method to prepare a warm-started quantum state from measurements with an iterative framework to enhance the quantum approximate optimisation algorithm (QAOA). The numerical simulations show the method can effectively address…

Quantum Physics · Physics 2025-02-17 Haomu Yuan , Songqinghao Yang , Crispin H. W. Barnes

Variational quantum algorithm (VQA), which is comprised of a classical optimizer and a parameterized quantum circuit, emerges as one of the most promising approaches for harvesting the power of quantum computers in the noisy intermediate…

Quantum Physics · Physics 2021-12-01 Samuel Stein , Yufei Ding , Nathan Wiebe , Bo Peng , Karol Kowalski , Nathan Baker , James Ang , Ang Li

Machine learning techniques have achieved impressive results in recent years and the possibility of harnessing the power of quantum physics opens new promising avenues to speed up classical learning methods. Rather than viewing classical…

Quantum Physics · Physics 2025-01-10 Johannes Nokkala , Gian Luca Giorgi , Roberta Zambrini

Variational quantum eigensolver (VQE) is regarded as a promising candidate of hybrid quantum-classical algorithm for the near-term quantum computers. Meanwhile, VQE is confronted with a challenge that statistical error associated with the…

Quantum Physics · Physics 2023-12-12 Ken N. Okada , Keita Osaki , Kosuke Mitarai , Keisuke Fujii

Quantum error mitigation (QEM) is critical for harnessing the potential of near-term quantum devices. Particularly, QEM protocols can be designed based on machine learning, where the mapping between noisy computational outputs and ideal…

Quantum Physics · Physics 2024-12-13 Ruiqi Zhang , Yuguo Shao , Fuchuan Wei , Song Cheng , Zhaohui Wei , Zhengwei Liu

Exploring quantum applications of near-term quantum devices is a rapidly growing field of quantum information science with both theoretical and practical interests. A leading paradigm to establish such near-term quantum applications is…

Quantum Physics · Physics 2022-08-16 Hao-Kai Zhang , Chengkai Zhu , Geng Liu , Xin Wang

Artificial intelligent language-model based coding agents have significantly changed the way we interact with computers in our day-to-day, as it is common to use them to create, improve, and run programming scripts only using natural…

Structure-based virtual screening must address a combinatorial explosion arising from up to 10^60 drug-like molecules, multiple conformations of proteins and ligands, and all possible spatial translations and rotations of ligands within the…

Quantum Physics · Physics 2025-05-14 Pei-Kun Yang

We investigate a classical formulation of the Quantum Approximate Optimization Algorithm (QAOA), realized as a Hamiltonian dynamical system of classical kicked tops, which we call the Variational Iterative Rotation Algorithm (VIRAL). The…

Disordered Systems and Neural Networks · Physics 2026-04-03 Flaviano Morone , Andrew D. Kent , Dries Sels

The variational quantum eigensolver (VQE) is a promising algorithm for demonstrating quantum advantage in the noisy intermediate-scale quantum (NISQ) era. However, optimizing VQE from random initial starting parameters is challenging due to…

Quantum Physics · Physics 2023-10-20 Abid Khan , Bryan K. Clark , Norm M. Tubman