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Large Language Models (LLMs) are increasingly used in clinical settings, where sensitivity to linguistic uncertainty can influence diagnostic interpretation and decision-making. Yet little is known about where such epistemic cues are…

Computation and Language · Computer Science 2025-12-01 Srivarshinee Sridhar , Raghav Kaushik Ravi , Kripabandhu Ghosh

In this paper, we study the problem of uncertainty estimation and calibration for LLMs. We begin by formulating the uncertainty estimation problem, a relevant yet underexplored area in existing literature. We then propose a supervised…

Machine Learning · Computer Science 2024-10-24 Linyu Liu , Yu Pan , Xiaocheng Li , Guanting Chen

ML models have errors when used for predictions. The errors are unknown but can be quantified by model uncertainty. When multiple ML models are trained using the same training points, their model uncertainties may be statistically…

Machine Learning · Statistics 2025-09-23 Xiaoping Du

We consider a semiparametric mixture of two univariate density functions where one of them is known while the weight and the other function are unknown. Such mixtures have a history of application to the problem of detecting differentially…

Statistics Theory · Mathematics 2017-08-01 Zhou Shen , Michael Levine , Zuofeng Shang

Despite their capabilities, Multimodal Large Language Models (MLLMs) may produce plausible but erroneous outputs, hindering reliable deployment. Accurate uncertainty metrics could enable escalation of unreliable queries to human experts or…

Artificial Intelligence · Computer Science 2026-03-02 Gregory Kang Ruey Lau , Hieu Dao , Nicole Kan Hui Lin , Bryan Kian Hsiang Low

The proliferation of open-source Large Language Models (LLMs) from various institutions has highlighted the urgent need for comprehensive evaluation methods. However, current evaluation platforms, such as the widely recognized HuggingFace…

Computation and Language · Computer Science 2024-11-01 Fanghua Ye , Mingming Yang , Jianhui Pang , Longyue Wang , Derek F. Wong , Emine Yilmaz , Shuming Shi , Zhaopeng Tu

Large language models (LLMs) have revolutionized the field of natural language processing with their impressive reasoning and question-answering capabilities. However, these models are sometimes prone to generating credible-sounding but…

Computation and Language · Computer Science 2026-04-21 Ranganath Krishnan , Piyush Khanna , Omesh Tickoo

Large Language Models have emerged as prime candidates to tackle misinformation mitigation. However, existing approaches struggle with hallucinations and overconfident predictions. We propose an uncertainty quantification framework that…

Computation and Language · Computer Science 2024-02-01 Mauricio Rivera , Jean-François Godbout , Reihaneh Rabbany , Kellin Pelrine

Sequence-to-sequence models are a powerful workhorse of NLP. Most variants employ a softmax transformation in both their attention mechanism and output layer, leading to dense alignments and strictly positive output probabilities. This…

Computation and Language · Computer Science 2019-06-14 Ben Peters , Vlad Niculae , André F. T. Martins

In the drug discovery process, where experiments can be costly and time-consuming, computational models that predict drug-target interactions are valuable tools to accelerate the development of new therapeutic agents. Estimating the…

Machine Learning · Computer Science 2024-07-22 Hannah Rosa Friesacher , Ola Engkvist , Lewis Mervin , Yves Moreau , Adam Arany

Large Language Models (LLMs) are prone to generating fluent but incorrect content, known as confabulation, which poses increasing risks in multi-turn or agentic applications where outputs may be reused as context. In this work, we…

Computation and Language · Computer Science 2026-03-18 Tianyi Zhou , Johanne Medina , Sanjay Chawla

The generation of texts using Large Language Models (LLMs) is inherently uncertain, with sources of uncertainty being not only the generation of texts, but also the prompt used and the downstream interpretation. Within this work, we provide…

Machine Learning · Computer Science 2026-03-30 Steffen Herbold , Florian Lemmerich

Large Language Models (LLMs) have been widely employed in programming language analysis to enhance human productivity. Yet, their reliability can be compromised by various code distribution shifts, leading to inconsistent outputs. While…

Software Engineering · Computer Science 2024-02-12 Yufei Li , Simin Chen , Yanghong Guo , Wei Yang , Yue Dong , Cong Liu

With an eye towards human-centered automation, we contribute to the development of a systematic means to infer features of human decision-making from behavioral data. Motivated by the common use of softmax selection in models of human…

Optimization and Control · Mathematics 2015-09-01 Paul Reverdy , Naomi E. Leonard

Masked diffusion language models (MDLMs) have emerged as a promising alternative to dominant autoregressive approaches. Although they achieve competitive performance on several tasks, a substantial gap remains in open-ended text generation.…

Computation and Language · Computer Science 2026-02-02 Mengyu Ye , Ryosuke Takahashi , Keito Kudo , Jun Suzuki

Multimodal semantic understanding often has to deal with uncertainty, which means the obtained messages tend to refer to multiple targets. Such uncertainty is problematic for our interpretation, including inter- and intra-modal uncertainty.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Yatai Ji , Junjie Wang , Yuan Gong , Lin Zhang , Yanru Zhu , Hongfa Wang , Jiaxing Zhang , Tetsuya Sakai , Yujiu Yang

Small language models (SLMs) have been increasingly deployed in edge devices and other resource-constrained settings. However, these models make confident mispredictions and produce unstable output, making them risky for factual and…

Artificial Intelligence · Computer Science 2026-04-07 Adeyemi Adeseye , Aisvarya Adeseye , Hannu Tenhunen , Jouni Isoaho

Large language models (LLMs) have transformed natural language processing, but their reliable deployment requires effective uncertainty quantification (UQ). Existing UQ methods are often heuristic and lack a probabilistic interpretation.…

Computation and Language · Computer Science 2025-11-06 Haoyi Song , Ruihan Ji , Naichen Shi , Fan Lai , Raed Al Kontar

Recent advances in natural language processing (NLP) have opened up greater opportunities to enable fine-tuned large language models (LLMs) to behave as more powerful interactive agents through improved instruction-following ability.…

Machine Learning · Computer Science 2025-10-27 Jerry Huang , Peng Lu , Qiuhao Zeng

Large language models(LLMs) excel at text generation and knowledge question-answering tasks, but they are prone to generating hallucinated content, severely limiting their application in high-risk domains. Current hallucination detection…

Computation and Language · Computer Science 2025-12-25 Shize Liang , Hongzhi Wang