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In this work, we propose Oph-Guid-RAG, a multimodal visual RAG system for ophthalmology clinical question answering and decision support. We treat each guideline page as an independent evidence unit and directly retrieve page images,…

Artificial Intelligence · Computer Science 2026-03-24 Shuying Chen , Sen Cui , Zhong Cao

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

We propose Retrieval Augmented Generation (RAG) as an approach for automated radiology report writing that leverages multimodally aligned embeddings from a contrastively pretrained vision language model for retrieval of relevant candidate…

Computation and Language · Computer Science 2023-05-08 Mercy Ranjit , Gopinath Ganapathy , Ranjit Manuel , Tanuja Ganu

Automated radiology report generation has gained increasing attention with the rise of deep learning and large language models. However, fully generative approaches often suffer from hallucinations and lack clinical grounding, limiting…

Quantitative Methods · Quantitative Biology 2026-05-01 Himadri S Samanta

While Retrieval Augmented Generation (RAG) is now widely adopted to enhance LLMs, evaluating its true performance benefits in a reproducible and interpretable way remains a major hurdle. Existing methods often fall short: they lack domain…

Information Retrieval · Computer Science 2025-08-11 Jiaxuan Liang , Shide Zhou , Kailong Wang

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

Despite Retrieval-Augmented Generation (RAG) showing promising capability in leveraging external knowledge, a comprehensive evaluation of RAG systems is still challenging due to the modular nature of RAG, evaluation of long-form responses…

Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plans. Methods and Materials: We curated a multi-protocol…

Performance evaluation of Retrieval-Augmented Generation (RAG) systems within enterprise environments is governed by multi-dimensional and composite factors extending far beyond simple final accuracy checks. These factors include reasoning…

Computation and Language · Computer Science 2026-04-06 Kenichirou Narita , Siqi Peng , Taku Fukui , Moyuru Yamada , Satoshi Munakata , Satoru Takahashi

Radiology report generation (RRG) aims to automatically produce diagnostic reports from medical images, with the potential to enhance clinical workflows and reduce radiologists' workload. While recent approaches leveraging multimodal large…

Artificial Intelligence · Computer Science 2025-05-16 Ziruo Yi , Ting Xiao , Mark V. Albert

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Retrieval-Augmented Generation (RAG) has emerged as a powerful paradigm for enhancing the capabilities of large language models. However, existing RAG evaluation predominantly focuses on text retrieval and relies on opaque, end-to-end…

Information Retrieval · Computer Science 2025-05-19 Chuan Xu , Qiaosheng Chen , Yutong Feng , Gong Cheng

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Vision-language retrieval-augmented generation (RAG) has become an effective approach for tackling Knowledge-Based Visual Question Answering (KB-VQA), which requires external knowledge beyond the visual content presented in images. The…

Information Retrieval · Computer Science 2025-09-15 Wei Yang , Jingjing Fu , Rui Wang , Jinyu Wang , Lei Song , Jiang Bian

Retrieval-augmented generation (RAG) combines document retrieval with large language models to produce responses grounded in external evidence. While several R packages support core components of RAG workflows, integrated evaluation of RAG…

Computation · Statistics 2026-04-28 Muhammad Aimal Rehman , Zhili Lu , Chi-Kuang Yeh

With the ever-increasing demands on Question Answering (QA) systems for IT operations and maintenance, an efficient and supervised fine-tunable framework is necessary to ensure the data security, private deployment and continuous upgrading.…

Artificial Intelligence · Computer Science 2025-06-04 Tianyang Zhang , Zhuoxuan Jiang , Shengguang Bai , Tianrui Zhang , Lin Lin , Yang Liu , Jiawei Ren

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

Artificial Intelligence · Computer Science 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo
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