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This study investigates the influence of different types of non-pharmaceutical interventions (NPIs) on epidemic progression using SIR compartmental models. We analyze the optimization of two distinct targets: the final epidemic size and the…

Populations and Evolution · Quantitative Biology 2026-04-10 Eric Rozán , Marcelo N Kuperman , Sebastián Bouzat

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…

Populations and Evolution · Quantitative Biology 2021-03-04 Naoya Fujiwara , Tomokatsu Onaga , Takayuki Wada , Shouhei Takeuchi , Junji Seto , Tomoki Nakaya , Kazuyuki Aihara

In fighting infectious diseases posing a global health threat, ranging from influenza to Zika, non-pharmaceutical interventions (NPI), such as social distancing and face covering, remain mitigation measures public health can resort to.…

Physics and Society · Physics 2024-04-12 Alina Glaubitz , Feng Fu

Non-pharmaceutical interventions (NPIs) such as quarantine, self-isolation, social distancing, and virus-contact tracing can greatly reduce the spread of the virus during a pandemic. In the wave of the COVID-19 pandemic, many countries have…

Physics and Society · Physics 2020-12-16 Jingjing He , Xuefei Guan , Xiaochang Duan , Tian Shen , Jing Lin

During the recent pandemic, a rise in COVID-19 cases was followed by a decline in influenza. In the absence of cross-immunity, a potential explanation for the observed pattern is behavioral: non-pharmaceutical interventions (NPIs) designed…

Dynamical Systems · Mathematics 2026-04-20 Leah LeJeune , Omar Saucedo , Lauren M. Childs , Navid Ghaffarzadegan

Infectious diseases and human behavior are intertwined. On one side, our movements and interactions are the engines of transmission. On the other, the unfolding of viruses might induce changes to our daily activities. While intuitive, our…

Physics and Society · Physics 2021-06-02 Nicola Perra

This paper introduces a dynamic panel SIR (DP-SIR) model to investigate the impact of non-pharmaceutical interventions (NPIs) on the COVID-19 transmission dynamics with panel data from 9 countries across the globe. By constructing scenarios…

Populations and Evolution · Quantitative Biology 2021-06-07 Xiaohui Chen , Ziyi Qiu

Transmission rates in epidemic outbreaks may vary over time depending on the societal response. Non-pharmacological mitigation strategies such as social distancing and the adoption of protective equipment aim precisely at reducing…

Populations and Evolution · Quantitative Biology 2020-12-24 Elisa Franco

Non-pharmaceutical interventions (NPIs) are crucial for controlling pandemics, but existing research often overlooks the heterogeneity of individual behavior, which can lead to inaccurate evaluations of the effectiveness of strategies. In…

Physics and Society · Physics 2026-03-09 Xihan Zhang , Yuqing Liu , Chen Zhao , Guijun Li

Countries around the world implement nonpharmaceutical interventions (NPIs) to mitigate the spread of COVID-19. Design of efficient NPIs requires identification of the structure of the disease transmission network. We here identify the key…

Populations and Evolution · Quantitative Biology 2021-05-18 Simon Syga , Diana David-Rus , Yannik Schälte , Michael Meyer-Hermann , Haralampos Hatzikirou , Andreas Deutsch

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

Non-pharmacologic interventions (NPIs) are one method to mitigate the spread and effects of the COVID-19 pandemic in the United States. NPIs promote protective actions to reduce exposure risk and can reduce mobility patterns within…

Physics and Society · Physics 2021-07-16 Natalie Coleman , Xinyu Gao , Jared DeLeon , Ali Mostafavi

We combine infectious disease transmission and the non-pharmaceutical intervention (NPI) response to disease incidence into one closed model consisting of two coupled delay differential equations for the incidence rate and the…

Quantitative Methods · Quantitative Biology 2021-02-24 Kristoffer Rypdal

This paper considers the problem of designing non-pharmaceutical intervention (NPI) strategies, such as masking and social distancing, to slow the spread of a viral epidemic. We formulate the problem of jointly minimizing the infection…

Systems and Control · Electrical Eng. & Systems 2024-12-02 Shiyu Cheng , Luyao Niu , Bhaskar Ramasubramanian , Andrew Clark , Radha Poovendran

Pharmaceutical and non-pharmaceutical interventions (NPIs) have been crucial for controlling COVID-19. They are complemented by voluntary health-protective behaviour, building a complex interplay between risk perception, behaviour, and…

Studies on how to model the interplay between diseases and behavioral responses (so-called coupled disease-behavior interaction) have attracted increasing attention. Owing to the lack of obvious clinical evidence of diseases, or the…

Physics and Society · Physics 2016-08-24 Hai-Feng Zhang , Jia-Rong Xie , Han-Shuang Chen , Can Liu , Michael Small

To contain the propagation of emerging diseases that are transmissible from human to human, non-pharmaceutical interventions (NPIs) aimed at reducing the interactions between humans are usually implemented. One example of the latter kind of…

Physics and Society · Physics 2021-05-21 Paulo Cesar Ventura , Alberto Aleta , Francisco Aparecido Rodrigues , Yamir Moreno

The effectiveness of non-pharmaceutical interventions to curb the spread of SARS-CoV-2 is determined by numerous contextual factors, including adherence. Conventional wisdom holds that the effectiveness of protective behaviour such as…

Physics and Society · Physics 2022-09-26 Peter Klimek , Katharina Ledebur , Stefan Thurner

Motivated by epidemics such as COVID-19, we study the spread of a contagious disease when behavior responds to the disease's prevalence. We extend the SIR epidemiological model to include endogenous meeting rates. Individuals benefit from…

Populations and Evolution · Quantitative Biology 2023-09-25 Krishna Dasaratha

We consider an epidemic process on adaptive activity-driven temporal networks, with adaptive behaviour modelled as a change in activity and attractiveness due to infection. By using a mean-field approach, we derive an analytical estimate of…

Physics and Society · Physics 2020-09-02 Marco Mancastroppa , Raffaella Burioni , Vittoria Colizza , Alessandro Vezzani
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