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The segmentation and tracking of living cells play a vital role within the biomedical domain, particularly in cancer research, drug development, and developmental biology. These are usually tedious and time-consuming tasks that are…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rüveyda Yilmaz , Dennis Eschweiler , Johannes Stegmaier

Convolutional neural networks (CNNs) have gained tremendous success in solving complex inverse problems. The aim of this work is to develop a novel CNN framework to reconstruct video sequence of dynamic live cells captured using a…

Computer Vision and Pattern Recognition · Computer Science 2020-10-29 Thanh Nguyen , Yujia Xue , Yunzhe Li , Lei Tian , George Nehmetallah

Cell tracking remains a pivotal yet challenging task in biomedical research. The full potential of deep learning for this purpose is often untapped due to the limited availability of comprehensive and varied training data sets. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Moritz Sturm , Lorenzo Cerrone , Fred A. Hamprecht

Methods allowing the synthesis of realistic cell shapes could help generate training data sets to improve cell tracking and segmentation in biomedical images. Deep generative models for cell shape synthesis require a light-weight and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 David Wiesner , Julian Suk , Sven Dummer , David Svoboda , Jelmer M. Wolterink

Cell detection and tracking are paramount for bio-analysis. Recent approaches rely on the tracking-by-model evolution paradigm, which usually consists of training end-to-end deep learning models to detect and track the cells on the frames…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Lucas N. Kirsten , Cláudio R. Jung

With the widespread of user-generated Internet videos, emotion recognition in those videos attracts increasing research efforts. However, most existing works are based on framelevel visual features and/or audio features, which might fail to…

Computer Vision and Pattern Recognition · Computer Science 2016-08-04 Haimin Zhang , Min Xu

Data-driven cell tracking and segmentation methods in biomedical imaging require diverse and information-rich training data. In cases where the number of training samples is limited, synthetic computer-generated data sets can be used to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 David Wiesner , Julian Suk , Sven Dummer , Tereza Nečasová , Vladimír Ulman , David Svoboda , Jelmer M. Wolterink

Recently, video classification attracts intensive research efforts. However, most existing works are based on framelevel visual features, which might fail to model the temporal information, e.g. characteristics accumulated along time. In…

Computer Vision and Pattern Recognition · Computer Science 2016-08-18 Haimin Zhang

Biomedical research increasingly relies on 3D cell culture models and AI-based analysis can potentially facilitate a detailed and accurate feature extraction on a single-cell level. However, this requires for a precise segmentation of 3D…

Image and Video Processing · Electrical Eng. & Systems 2024-08-30 Roman Bruch , Mario Vitacolonna , Elina Nürnberg , Simeon Sauer , Rüdiger Rudolf , Markus Reischl

We present a domain adaptation of video diffusion models to generate highly realistic time-lapse microscopy videos of cell division in HeLa cells. Although state-of-the-art generative video models have advanced significantly for natural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Alexander Holmberg , Nils Mechtel , Wei Ouyang

We propose manvr3d, a novel VR-ready platform for interactive human-in-the-loop cell tracking. We utilize VR controllers and eye-tracking hardware to facilitate rapid ground truth generation and proofreading for deep learning-based cell…

Human-Computer Interaction · Computer Science 2026-01-06 Samuel Pantze , Jean-Yves Tinevez , Matthew McGinity , Ulrik Günther

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

Recent advances in generative video modeling, driven by large-scale datasets and powerful architectures, have yielded remarkable visual realism. However, emerging evidence suggests that simply scaling data and model size does not endow…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Ying Shen , Jerry Xiong , Tianjiao Yu , Ismini Lourentzou

The success of deep learning-based generative models in producing realistic images, videos, and audios has led to a crucial consideration: how to effectively assess the quality of synthetic samples. While the Fr\'{e}chet Inception Distance…

Machine Learning · Computer Science 2024-03-12 Yang Chen , Dustin J. Kempton , Rafal A. Angryk

Video diffusion models have achieved impressive results in natural scene generation, yet they struggle to generalize to scientific phenomena such as fluid simulations and meteorological processes, where underlying dynamics are governed by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Qinglong Cao , Xirui Li , Ding Wang , Chao Ma , Yuntian Chen , Xiaokang Yang

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Medical imaging applications are highly specialized in terms of human anatomy, pathology, and imaging domains. Therefore, annotated training datasets for training deep learning applications in medical imaging not only need to be highly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Arjun Krishna , Ge Wang , Klaus Mueller

Recent advances in bioimaging have provided scientists a superior high spatial-temporal resolution to observe dynamics of living cells as 3D volumetric videos. Unfortunately, the 3D biomedical video analysis is lagging, impeded by resource…

Computer Vision and Pattern Recognition · Computer Science 2021-06-23 Mengyang Zhao , Quan Liu , Aadarsh Jha , Ruining Deng , Tianyuan Yao , Anita Mahadevan-Jansen , Matthew J. Tyska , Bryan A. Millis , Yuankai Huo

Deep Learning (DL) models have been successfully applied to many applications including biomedical cell segmentation and classification in histological images. These models require large amounts of annotated data which might not always be…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Roberto Basla , Loris Giulivi , Luca Magri , Giacomo Boracchi

Recognizing pain in video is crucial for improving patient-computer interaction systems, yet traditional data collection in this domain raises significant ethical and logistical challenges. This study introduces a novel approach that…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Jonas Nasimzada , Jens Kleesiek , Ken Herrmann , Alina Roitberg , Constantin Seibold
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