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Related papers: Sibyl-AutoResearch: Autonomous Research Needs Self…

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Automating scientific discovery requires more than generating papers from ideas. Real research is iterative: hypotheses are challenged from multiple perspectives, experiments fail and inform the next attempt, and lessons accumulate across…

Database systems often rely on historical query traces to perform workload-based performance tuning. However, real production workloads are time-evolving, making historical queries ineffective for optimizing future workloads. To address…

Scientific research is being reshaped by AI systems that move beyond isolated assistance toward longer-horizon workflows spanning literature grounding, hypothesis generation, experimentation, validation, reporting, and revision. This shift…

This paper argues that workflow closure is not scientific closure in auto-research systems. Current systems can increasingly complete research-like loops internally, moving from idea generation to experiment execution, writing, and…

Software Engineering · Computer Science 2026-05-27 Shuai Wang , Xinyuan Tian , Pangpang Liu , Yize Zhao

Designing aligned and robust rewards for open-ended generation remains a key barrier to RL post-training. Rubrics provide structured, interpretable supervision, but scaling rubric construction is difficult: expert rubrics are costly,…

The automation of chemical research through self-driving laboratories (SDLs) promises to accelerate scientific discovery, yet the reliability and granular performance of the underlying AI agents remain critical, under-examined challenges.…

Artificial Intelligence · Computer Science 2025-10-01 Gihan Panapitiya , Emily Saldanha , Heather Job , Olivia Hess

Existing agents based on large language models (LLMs) demonstrate robust problem-solving capabilities by integrating LLMs' inherent knowledge, strong in-context learning and zero-shot capabilities, and the use of tools combined with…

Artificial Intelligence · Computer Science 2024-07-17 Yulong Wang , Tianhao Shen , Lifeng Liu , Jian Xie

Software engineering practices for validating autonomous cyber-physical systems (e.g., Uncrewed Aerial Vehicles) remain fragmented across scenario design, simulation execution, and telemetry analysis, limiting traceability between…

Software Engineering · Computer Science 2026-04-14 Ankit Agrawal , Jithin Garapati , Bohan Zhang

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

This report describes ARIS (Auto-Research-in-sleep), an open-source research harness for autonomous research, including its architecture, assurance mechanisms, and early deployment experience. The performance of agent systems built on LLMs…

Software Engineering · Computer Science 2026-05-06 Ruofeng Yang , Yongcan Li , Shuai Li

Comprehensive evaluation of mobile agents can significantly advance their development and real-world applicability. However, existing benchmarks lack practicality and scalability due to the extensive manual effort in defining task reward…

Artificial Intelligence · Computer Science 2025-09-25 Jiahui Sun , Zhichao Hua , Yubin Xia

Advances in robotic control and sensing have propelled the rise of automated scientific laboratories capable of high-throughput experiments. However, automated scientific laboratories are currently limited by human intuition in their…

Machine Learning · Computer Science 2024-12-18 Saaketh Desai , Sadhvikas Addamane , Jeffrey Y. Tsao , Igal Brener , Laura P. Swiler , Remi Dingreville , Prasad P. Iyer

Developing and fielding complex systems requires proof that they are reliably correct with respect to their design and operating requirements. Especially for autonomous systems which exhibit unanticipated emergent behavior, fully…

Software Engineering · Computer Science 2024-02-28 Matthew Litton , Doron Drusinsky , James Bret Michael

Hybrid storage systems (HSS) use multiple different storage devices to provide high and scalable storage capacity at high performance. Recent research proposes various techniques that aim to accurately identify performance-critical data to…

Large language models are moving scientific research from text assistance toward agentic workflows, yet biological research requires strong object validation, methodological suitability, reproducibility, and auditability. Prompt…

Quantitative Methods · Quantitative Biology 2026-05-25 Zhenyu Ma , Yuyang Song , Chunyi Yang , Jingyi Zhu , Limei Xu , Min Xiao , Xukai Jiang

Recent autonomous research systems -- AI-Scientist, PaperOrchestra, AutoSOTA, DeepResearch, InternAgent, ResearchAgent and others -- show LLM agents can ideate, run experiments and write papers, but each fixes a particular control-flow…

Software Engineering · Computer Science 2026-05-08 Yuchen Wang , Zhongzhi Luan

Autonomous research systems capable of generating complete scientific manuscripts have advanced rapidly, yet robust and realistic evaluation frameworks have failed to keep pace. To bridge this gap, we introduce MLReplicate, an end-to-end…

Machine Learning · Computer Science 2026-05-19 Sasi Kiran Gaddipati , Diyana Muhammed , Farhana Keya , Gollam Rabby , Sören Auer

Recommender-systems research has accelerated model and evaluation advances, yet largely neglects automating the research process itself. We argue for a shift from narrow AutoRecSys tools -- focused on algorithm selection and hyper-parameter…

Information Retrieval · Computer Science 2025-10-22 Joeran Beel , Bela Gipp , Tobias Vente , Moritz Baumgart , Philipp Meister

In practical LLM applications, users repeatedly express stable preferences and requirements, such as reducing hallucinations, following institutional writing conventions, or avoiding overly technical wording, yet such interaction experience…

Artificial Intelligence · Computer Science 2026-03-06 Yutao Yang , Junsong Li , Qianjun Pan , Bihao Zhan , Yuxuan Cai , Lin Du , Jie Zhou , Kai Chen , Qin Chen , Xin Li , Bo Zhang , Liang He

We present Camyla, a system for fully autonomous research within the scientific domain of medical image segmentation. Camyla transforms raw datasets into literature-grounded research proposals, executable experiments, and complete…

Artificial Intelligence · Computer Science 2026-04-14 Yifan Gao , Haoyue Li , Feng Yuan , Xin Gao , Weiran Huang , Xiaosong Wang
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