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Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…
Confocal laser endomicroscopy (CLE) allow on-the-fly in vivo intraoperative imaging in a discreet field of view, especially for brain tumors, rather than extracting tissue for examination ex vivo with conventional light microscopy.…
Computational pathology is a domain that aims to develop algorithms to automatically analyze large digitized histopathology images, called whole slide images (WSI). WSIs are produced scanning thin tissue samples that are stained to make…
3D printing has revolutionized the manufacturing of volumetric components and structures in many areas. Different technologies have been developed including light-induced techniques based on the photopolymerization of liquid resins. In…
Next-generation nano and quantum devices have increasingly complex 3D structure. As the dimensions of these devices shrink to the nanoscale, their performance is often governed by interface quality or precise chemical or dopant composition.…
Vision Transformers (ViTs) have emerged as state-of-the-art models for various vision tasks recently. However, their heavy computation costs remain daunting for resource-limited devices. To address this, researchers have dedicated…
Double staining in histopathology, particularly for metaplastic breast cancer, typically employs H&E and P63 dyes. However, P63's tissue damage and high cost necessitate alternative methods. This study introduces xAI-CycleGAN, an advanced…
State-of-the-art computer- and robot-assisted surgery systems heavily depend on intraoperative imaging technologies such as CT and fluoroscopy to generate detailed 3D visualization of the patient's anatomy. While imaging techniques are…
While Masked Image Modeling (MIM) has revolutionized fields of computer vision, its adoption in 3D medical image computing has been limited by the use of random masking, which overlooks the density of anatomical objects. To address this…
Ultrasound tomography generally struggles to reconstruct high-contrast and/or extended-range problems. A prime example is site-specific in-vivo bone imaging, crucial for accurately assessing the risk of life-threatening fractures, which are…
Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…
Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challenging…
Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…
It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…
Current pathology workflow involves staining of thin tissue slices, which otherwise would be transparent, followed by manual investigation under the microscope by a trained pathologist. While the hematoxylin and eosin (H&E) stain is…
For 3D object detection, both camera and lidar have been demonstrated to be useful sensory devices for providing complementary information about the same scenery with data representations in different modalities, e.g., 2D RGB image vs 3D…
Electron tomography offers important three-dimensional (3D) structural information which cannot be observed by two-dimensional imaging. By combining annular dark field scanning transmission electron microscopy (ADF-STEM) with aberration…
This work presents a proof-of-concept solution designed to improve the accuracy of radiographic feature characterisation in pre-surgical CT/MR volumes. The solution involves 3D co-location of 2D digital histology slides within ex-vivo,…
As Micro-CT technology continues to refine its characterization of material microstructures, industrial CT ultra-precision inspection is generating increasingly large datasets, necessitating solutions to the trade-off between accuracy and…
Early diagnosis of prostate cancer significantly improves a patient's 5-year survival rate. Biopsy of small prostate cancers is improved with image-guided biopsy. MRI-ultrasound fusion-guided biopsy is sensitive to smaller tumors but is…