Related papers: AOP-Wiki EMOD 3.0: Data Model Expansions and Conte…
Adverse Outcome Pathways (AOPs) are an important knowledge framework in toxicological research and risk assessment. In recent years, large language models (LLMs) have gradually been applied to AOP-related question answering and mechanistic…
The Observational Medical Outcomes Partnership Common Data Model (OMOP CDM), maintained by the Observational Health Data Sciences and Informatics (OHDSI) collaboration, enabled the harmonisation of electronic health records data of nearly…
Large language models are increasingly being used to support network operations (NetOps) and artificial intelligence for IT operations (AIOps), including incident investigation, root-cause analysis, configuration synthesis, and limited…
The paper tackles the issue of mapping logic axioms formalised in the Ontology Web Language (OWL) within the Object-Oriented Programming (OOP) paradigm. The issues of mapping OWL axioms hierarchies and OOP objects hierarchies are due to…
Artificial intelligence operations (AIOps) play a pivotal role in identifying, mitigating, and analyzing anomalous system behaviors and alerts. However, the research landscape in this field remains limited, leaving significant gaps…
Motivation: Ontologies are widely used in biology for data annotation, integration, and analysis. In addition to formally structured axioms, ontologies contain meta-data in the form of annotation axioms which provide valuable pieces of…
We study learning control in an online reset-free lifelong learning scenario, where mistakes can compound catastrophically into the future and the underlying dynamics of the environment may change. Traditional model-free policy learning…
Parameter identification for mechanistic Ordinary Differential Equation (ODE) models underpins prediction and control in several applications, yet remains a manual and labor-intensive process: datasets are noisy and partial, models can be…
To address the global health threat of antimicrobial resistance, antimicrobial peptides (AMP) are being explored for their potent and promising ability to fight resistant pathogens. While artificial intelligence (AI) is being employed to…
Advances in machine learning methods for computer vision tasks have led to their consideration for safety-critical applications like autonomous driving. However, effectively integrating these methods into the automotive development…
On-policy distillation (OPD) trains a student on its own trajectories with token-level teacher feedback and often outperforms off-policy distillation and standard reinforcement learning. However, we find that its standard advantage weighted…
Large language model (LLM) agents offer a promising data-driven approach to automating Site Reliability Engineering (SRE), yet their enterprise deployment is constrained by three challenges: restricted access to proprietary data, unsafe…
Agentic artificial intelligence (AI) -- multi-agent systems that combine large language models with external tools and autonomous planning -- are rapidly transitioning from research laboratories into high-stakes domains. Our earlier "Basic"…
Agentic AI prototypes are being deployed across domains with increasing speed, yet no methodology for their structured design, governance, and prospective evaluation has been established. Existing AI documentation practices and guidelines…
The emergence of Agentic AI systems has outpaced the architectural thinking required to operate them effectively. These agents differ fundamentally from traditional software: their behavior is not fixed at deployment but continuously shaped…
Neuroevolution is a process of training neural networks (NN) through an evolutionary algorithm, usually to serve as a state-to-action mapping model in control or reinforcement learning-type problems. This paper builds on the Neuro Evolution…
OWLOOP is an Application Programming Interface (API) for using the Ontology Web Language (OWL) by the means of Object-Oriented Programming (OOP). It is common to design software architectures using the OOP paradigm for increasing their…
Anti-viral therapies are typically designed to target only the current strains of a virus, a myopic response. However, therapy-induced selective pressures drive the emergence of new viral strains, against which the original myopic therapies…
Background: Adverse Childhood Experiences (ACEs), a set of negative events and processes that a person might encounter during childhood and adolescence, have been proven to be linked to increased risks of a multitude of negative health…
This position paper argues that optimization problem solving can transition from expert-dependent to evolutionary agentic workflows. Traditional optimization practices rely on human specialists for problem formulation, algorithm selection,…