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Micro-scale cilia play a vital role in mucociliary clearance (MCC) in the human respiratory airways. In this numerical study, we examine fluid transport driven by the active beating of a single filament immersed in a three-dimensional…

Fluid Dynamics · Physics 2026-02-02 Qian Mao , Umberto d'Ortona , Julien Favier

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

Soft Condensed Matter · Physics 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

This paper presents a theoretical study of a non-linear rheological fluid transport in an axisymmetric tube by cilia. However, an attempt has been made to explain the role of cilia motion on the transport of fluid through the ductus…

Fluid Dynamics · Physics 2023-12-22 S. Maiti , S. K. Pandey

When transported in confined geometries rigid fibers show interesting transport dynamics induced by friction with the top and bottom walls. Fiber flexibility causes an additional coupling between fiber deformation and transport and is…

Cilia are motile biological appendages that are driven to bend by internal shear stresses between tubulin filaments. A continuum model of ciliary material is constructed that incorporates the essential ciliary constraints: (1)…

Soft Condensed Matter · Physics 2013-05-29 Mark A. Peterson

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

Cilia and flagella are self-actuated microtubule-based structures that are present on many cell surfaces, ranging from the outer surface of single-cell organisms to the internal epithelial surfaces in larger animals. A fast and robust…

Fluid Dynamics · Physics 2020-04-08 Hanliang Guo , Hai Zhu , Shravan Veerapaneni

The fabric of porous and fractured media contains solid regions (grains) and voids. The space conducting fluids is a system of connected voids with variable geometries. Relative to the grain sizes, the voids can be voluminous with three…

Mathematical Physics · Physics 2025-01-16 Changhao Liu , Kiprian Berbatov , Majid Sedighi , Andrey P. Jivkov

A flexible membrane deforming its shape in time can self-propel in a viscous fluid. Alternatively, if the membrane is anchored, its deformation will lead to fluid transport. Past work in this area focused on situations where the deformation…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Eric Lauga

Air-permeable porous media hosts air within their pores. Upon removal from the interior of the material, these porous media have the tendency to reabsorb air from the surrounding, acting as a suction pump. Therefore, the technique used to…

The dynamics of colloidal suspension confined within porous materials strongly differs from that in the bulk. In particular, within porous materials, the presence of boundaries with complex shapes entangles the longitudinal and transverse…

Soft Condensed Matter · Physics 2021-11-16 P. Malgaretti , A. M. Puertas , I. Pagonabarraga

Mucociliary clearance in the lung is the primary defense mechanism that protects the airways from inhaled toxicants and infectious agents. The system consists of a viscoelastic mucus layer driven by motile cilia in a periciliary layer…

Fluid Dynamics · Physics 2016-06-10 Hanliang Guo , Eva Kanso

Ciliary flows are generated by a vast array of eukaryotic organisms, from unicellular algae to mammals, and occur in a range of different geometrical configurations. We employ a point torque -- or `rotlet' -- model to capture the…

Fluid-resistance limited transport of vesicles through narrow constrictions is a recurring theme in many biological and engineering applications. Inspired by the motor-driven movement of soft membrane-bound vesicles into closed neuronal…

Soft Condensed Matter · Physics 2020-04-15 Thomas G. Fai , Remy Kusters , Jens Harting , Chris H. Rycroft , L. Mahadevan

In tissues as diverse as amphibian skin and the human airway, the cilia that propel fluid are grouped in sparsely distributed multiciliated cells (MCCs). We investigate fluid transport in this "mosaic" architecture, with emphasis on the…

Soft Condensed Matter · Physics 2021-11-17 Francesco Boselli , Jerome Jullien , Eric Lauga , Raymond E. Goldstein

We use a one dimensional symmetric exclusion model to study pressure and osmosis driven flows through molecular-sized channels, such as biological membrane channels and zeolite pores. Analytic expressions are found for the steady-state flow…

Soft Condensed Matter · Physics 2008-02-03 Tom Chou

By numerical modeling we investigate fluid transport in low-Reynolds-number flow achieved with a special elastic filament or artifical cilium attached to a planar surface. The filament is made of superparamagnetic particles linked together…

Soft Condensed Matter · Physics 2008-11-25 Erik M. Gauger , Matthew Downton , Holger Stark

The macroscopic phenomenon of filtration is the separation between suspended and liquid phases and it takes place in natural environments (e.g. groundwater, soil, hyporheic zone) and industrial systems (e.g. filtration plants,…

To spontaneously break their intrinsic symmetry and self-propel at the micron scale, isotropic active colloidal particles and droplets exploit the non-linear convective transport of chemical solutes emitted/consumed at their surface by the…

Soft Condensed Matter · Physics 2023-06-22 Francesco Picella , Sebastien Michelin

When colloids flow in a narrow channel, the transport efficiency is controlled by the non-equilibrium interplay between colloid-wall interactions and hydrodynamics. In this paper, a general, unifying description of colloidal dispersion flow…

Fluid Dynamics · Physics 2018-06-12 Patrice Bacchin
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