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Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes,…

Long noncoding RNAs (lncRNAs) are a recently discovered class of non-protein coding RNAs which have now increasingly been shown to be involved in a wide variety of biological processes as regulatory molecules. Little is known regarding the…

Genomics · Quantitative Biology 2015-06-11 Saakshi Jalali , Deeksha Bhartiya , Vinod Scaria

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…

Machine Learning · Computer Science 2024-12-03 Elizabeth Remfry , Rafael Henkin , Michael R Barnes , Aakanksha Naik

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…

Machine Learning · Computer Science 2019-07-30 Ramin Ramazi , Christine Perndorfer , Emily Soriano , Jean-Philippe Laurenceau , Rahmatollah Beheshti

Type 2 diabetes mellitus (T2DM) is one of the most common diseases and a leading cause of death. The problem of early diagnosis of T2DM is challenging and necessary to prevent serious complications. This study proposes a novel neural…

Machine Learning · Computer Science 2023-01-20 Tayyab Nasir , Muhammad Kamran Malik

Type 2 diabetes mellitus (T2DM) is a chronic disease that often results in multiple complications. Risk prediction and profiling of T2DM complications is critical for healthcare professionals to design personalized treatment plans for…

Machine Learning · Computer Science 2019-04-03 Bin Liu , Ying Li , Soumya Ghosh , Zhaonan Sun , Kenney Ng , Jianying Hu

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

Over 30 million Americans are affected by Type II diabetes (T2D), a treatable condition with significant health risks. This study aims to develop and validate predictive models using machine learning (ML) techniques to estimate emergency…

Quantitative Methods · Quantitative Biology 2024-12-13 Javad M Alizadeh , Jay S Patel , Gabriel Tajeu , Yuzhou Chen , Ilene L Hollin , Mukesh K Patel , Junchao Fei , Huanmei Wu

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Type 2 Diabetes Mellitus (T2DM) remains a global health challenge, underscoring the need for early and accurate risk prediction. This study presents ECG-DiaNet, a multimodal deep learning model that integrates electrocardiogram (ECG)…

Machine Learning · Computer Science 2025-04-09 Farida Mohsen , Zubair Shah

The widespread application of machine learning techniques to biomedical data has produced many new insights into disease progression and improving clinical care. Inspired by the flexibility and interpretability of graphs (networks), as well…

Machine Learning · Computer Science 2023-12-27 Steven J. Krieg , Nitesh V. Chawla , Keith Feldman

Diabetic Retinopathy (DR) is a non-negligible eye disease among patients with Diabetes Mellitus, and automatic retinal image analysis algorithm for the DR screening is in high demand. Considering the resolution of retinal image is very…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Kang Zhou , Zaiwang Gu , Wen Liu , Weixin Luo , Jun Cheng , Shenghua Gao , Jiang Liu

Designing proper treatment plans to manage diabetes requires health practitioners to pay heed to the individuals remaining life along with the comorbidities affecting them. Older adults with Type 2 Diabetes Mellitus (T2DM) are prone to…

Machine Learning · Computer Science 2024-02-20 Ruchika Desure , Gutha Jaya Krishna

Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations…

Computational Engineering, Finance, and Science · Computer Science 2023-08-29 Yi Zhou , Meixuan Wu , Chengzhou Ouyang , Min Zhu

Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system whose molecular mechanisms remain incompletely understood. In this study, we developed an end-to-end machine learning pipeline to analyze transcriptomic…

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

Machine Learning · Computer Science 2026-01-21 Beyza Cinar , Louisa van den Boom , Maria Maleshkova

The rising prevalence of type 2 diabetes mellitus (T2DM) necessitates the development of predictive models for T2DM risk assessment. Artificial intelligence (AI) models are being extensively used for this purpose, but a comprehensive review…

Machine Learning · Computer Science 2023-05-29 Farida Mohsen , Hamada R. H. Al-Absi , Noha A. Yousri , Nady El Hajj , Zubair Shah

Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…

Machine Learning · Computer Science 2025-11-10 Esha Chowdhury

Early diagnosis of Type 2 Diabetes Mellitus (T2DM) is crucial to enable timely therapeutic interventions and lifestyle modifications. As the time available for clinical office visits shortens and medical imaging data become more widely…

Lipid nanoparticles (LNPs) are highly effective carriers for gene therapies, including mRNA and siRNA delivery, due to their ability to transport nucleic acids across biological membranes, low cytotoxicity, improved pharmacokinetics, and…

Biomolecules · Quantitative Biology 2025-06-06 Gaurav Kumar , Arezoo M. Ardekani