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Unbalanced optimal transport (UOT) provides a principled framework for modeling single-cell transitions and birth-death dynamics, but its high computational cost limits scalability to large-scale datasets. Although single-cell data often…

Machine Learning · Computer Science 2026-05-19 Qiangwei Peng , Lezhi Chen , Peijie Zhou

Quadratic Unconstrained Binary Optimization (QUBO) provides a versatile framework for representing NP-hard combinatorial problems, yet existing solvers often face trade-offs among speed, accuracy, and scalability. In this work, we introduce…

Quantum Physics · Physics 2025-06-06 Jiecheng Yang , Ding Wang , Xiang Zhao , Hairui Zhang , Ming Gao , Lin Yang

Classical evolutionary approaches for multiobjective optimization are quite accurate but incur a lot of queries to the objectives; this can be prohibitive when objectives are expensive oracles. A sample-efficient approach to solving…

Optimization and Control · Mathematics 2025-02-18 Ashwin Renganathan , Kade E. Carlson

We propose a novel algorithm for optimizing multivariate linear threshold functions as split functions of decision trees to create improved Random Forest classifiers. Standard tree induction methods resort to sampling and exhaustive search…

Machine Learning · Computer Science 2015-06-26 Mohammad Norouzi , Maxwell D. Collins , David J. Fleet , Pushmeet Kohli

This work presents a novel tensor network algorithm for solving Quadratic Unconstrained Binary Optimization (QUBO) problems, Quadratic Unconstrained Discrete Optimization (QUDO) problems, and Tensor Quadratic Unconstrained Discrete…

This article proposes a formalism which unifies Hamiltonian simulation techniques from different fields. This formalism leads to a competitive method to construct the Hamiltonian simulation with a comprehensible, simple-to-implement circuit…

Quantum Physics · Physics 2025-01-22 Robin Ollive , Stephane Louise

Most of the existing clustering methods are based on a single granularity of information, such as the distance and density of each data. This most fine-grained based approach is usually inefficient and susceptible to noise. Therefore, we…

Machine Learning · Computer Science 2023-03-30 Jiang Xie , Shuyin Xia , Guoyin Wang , Xinbo Gao

The global optimization literature places large emphasis on reducing intractable optimization problems into more tractable structured optimization forms. In order to achieve this goal, many existing methods are restricted to optimization…

Optimization and Control · Mathematics 2025-04-28 Dimitris Bertsimas , Berk Öztürk

This research introduces an improved framework for constructing matrix product operators (MPOs) and tree tensor network operators (TTNOs), crucial tools in quantum simulations. A given (Hamiltonian) operator typically has a known symbolic…

Quantum Physics · Physics 2025-07-04 Hazar Çakır , Richard M. Milbradt , Christian B. Mendl

In the foreseeable future, toolchains for quantum computing should offer automatic means of transforming a high level problem formulation down to a hardware executable form. Thereby, it is crucial to find (multiple) transformation paths…

Quantum Physics · Physics 2025-10-13 Lukas Schmidbauer , Wolfgang Mauerer

Quadratic unconstrained binary optimization (QUBO) solvers can be applied to design an optimal structure to avoid resonance. QUBO algorithms that work on a classical or quantum device have succeeded in some industrial applications. However,…

Mesoscale and Nanoscale Physics · Physics 2022-09-29 Tadayoshi Matsumori , Masato Taki , Tadashi Kadowaki

In the last decade, machine learning-based approaches became capable of performing a wide range of complex tasks sometimes better than humans, demanding a fraction of the time. Such an advance is partially due to the exponential growth in…

Variational quantum circuits for image classification suffer from barren plateaus, while quantum kernel methods scale quadratically with dataset size. We propose an iterative framework based on Quadratic Unconstrained Binary Optimization…

Quantum Physics · Physics 2026-03-04 Mostafa Atallah , Rebekah Herrman

The Feedback-based Algorithm for Quantum Optimization (FALQON) offers a deterministic alternative to variational quantum algorithms by bypassing classical optimization loops. However, maintaining convergence on large problem instances often…

Multi-period stock-keeping unit (SKU) allocation in supply chains is a combinatorial optimization problem that is both NP-hard and operationally critical, requiring simultaneous attention to profitability, feasibility, and diversity.…

The optimization of front-end crude oil scheduling is a critical determinant of refinery profitability and operational stability. However, the coupling of discrete logistics events (e.g., vessel berthing) with continuous material flows…

Quantum Physics · Physics 2026-04-30 Jian Yang , Bohang Wang , Lina Wang , Jiacheng Chen , Gaoxiang Tang , Zihan Deng , Wending Zhao , Xianfeng Cai

The time-fractional optimal transport (OT) and mean-field planning (MFP) models are developed to describe the anomalous transport of the agents in a heterogeneous environment such that their densities are transported from the initial…

Optimization and Control · Mathematics 2023-09-06 Yiqun Li , Hong Wang , Wuchen Li

We present the MPS-JuliQAOA simulator, a user-friendly, open-source tool to simulate the Quantum Approximate Optimization Algorithm (QAOA) of any optimization problem that can be expressed as diagonal Hamiltonian. By leveraging…

Quantum Physics · Physics 2025-08-11 Sean Feeney , Reuben Tate , John Golden , Stephan Eidenbenz

As the basic model for very large scale integration (VLSI) routing, the Steiner minimal tree (SMT) can be used in various practical problems, such as wire length optimization, congestion, and time delay estimation. In this paper, a novel…

Neural and Evolutionary Computing · Computer Science 2018-11-27 Genggeng Liu , Zhen Zhuang , Wenzhong Guo , Naixue Xiong , Guolong Chen

Solving NP-hard constrained combinatorial optimization problems using quantum algorithms remains a challenging yet promising avenue toward quantum advantage. Variational Quantum Algorithms (VQAs), such as the Variational Quantum Eigensolver…

Quantum Physics · Physics 2025-07-28 Xin Wei Lee , Hoong Chuin Lau