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Diffusion models (DMs), lauded for their generative performance, are computationally prohibitive due to their billion-scale parameters and iterative denoising dynamics. Existing efficiency techniques, such as quantization, timestep…

Machine Learning · Computer Science 2026-01-21 Arani Roy , Shristi Das Biswas , Kaushik Roy

Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental context, obscuring nuances needed to assess data correctness and…

The rapid expansion of publicly-available medical data presents a challenge for clinicians and researchers alike, increasing the gap between the volume of scientific literature and its applications. The steady growth of studies and findings…

Artificial Intelligence · Computer Science 2025-08-06 Taine J. Elliott , Stephen P. Levitt , Ken Nixon , Martin Bekker

Pretrained biomedical vision-language models (VLMs) such as BioMedCLIP perform well on average but often degrade on challenging modalities where inter-class margins are small and acquisition-specific variations are pronounced, especially…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Mainak Singha , Tanisha Gupta , Ankit Jha , Muhammad Haris Khan , Sayantani Ghosh , Biplab Banerjee

The development of vision-language models (VLMs) is driven by large-scale and diverse multimodal datasets. However, progress toward generalist biomedical VLMs is limited by the lack of annotated, publicly accessible datasets across biology…

Objective: The paper focuses on development of robust and accurate processing solutions for continuous and cuff-less blood pressure (BP) monitoring. In this regard, a robust deep learning-based framework is proposed for computation of low…

Machine Learning · Computer Science 2022-01-03 Soheil Zabihi , Elahe Rahimian , Fatemeh Marefat , Amir Asif , Pedram Mohseni , Arash Mohammadi

With the advent of large language models (LLMs), the vast unstructured text within millions of academic papers is increasingly accessible for materials discovery, although significant challenges remain. While LLMs offer promising few- and…

Computation and Language · Computer Science 2025-09-30 Amit K Verma , Zhisong Zhang , Junwon Seo , Robin Kuo , Runbo Jiang , Emma Strubell , Anthony D Rollett

Automatic conversion of free-text radiology reports into structured data using Natural Language Processing (NLP) techniques is crucial for analyzing diseases on a large scale. While effective for tasks in widely spoken languages like…

Computation and Language · Computer Science 2024-05-24 Liam Hazan , Gili Focht , Naama Gavrielov , Roi Reichart , Talar Hagopian , Mary-Louise C. Greer , Ruth Cytter Kuint , Dan Turner , Moti Freiman

Pharmaceutical process design and development for generic, innovative, or personalized drugs have always been a time-consuming, costly, rigorous process, that involves multi-stage evaluation for better quality control and assurance. Large…

Emerging Technologies · Computer Science 2025-03-24 Leqi Lin , Xingyu Zhou , Kaiyuan Yang , Xizhong Chen

Universal medical image segmentation seeks to use a single foundational model to handle diverse tasks across multiple imaging modalities. However, existing approaches often rely heavily on manual visual prompts or retrieved reference…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Haoyun Chen , Fenghe Tang , Wenxin Ma , Shaohua Kevin Zhou

Objective: The majority of detailed patient information in real-world data (RWD) is only consistently available in free-text clinical documents. Manual curation is expensive and time-consuming. Developing natural language processing (NLP)…

Domain adaptation is a widely used method in natural language processing (NLP) to improve the performance of a language model within a specific domain. This method is particularly common in the biomedical domain, which sees regular…

Computation and Language · Computer Science 2024-09-05 Mathieu Laï-king , Patrick Paroubek

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yihang Fu , Ziyang Chen , Yiwen Ye , Xingliang Lei , Zhisong Wang , Yong Xia

Automated medical report generation has demonstrated the potential to significantly reduce the workload associated with time-consuming medical reporting. Recent generative representation learning methods have shown promise in integrating…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shuchang Ye , Mingyuan Meng , Mingjian Li , Dagan Feng , Usman Naseem , Jinman Kim

Recent progress in large language models (LLMs) has leveraged their in-context learning (ICL) abilities to enable quick adaptation to unseen biomedical NLP tasks. By incorporating only a few input-output examples into prompts, LLMs can…

Computation and Language · Computer Science 2025-08-12 Jun Wang , Zaifu Zhan , Qixin Zhang , Mingquan Lin , Meijia Song , Rui Zhang

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

Question answering over visually rich documents (VRDs) requires reasoning not only over isolated content but also over documents' structural organization and cross-page dependencies. However, conventional retrieval-augmented generation…

Computation and Language · Computer Science 2026-03-03 Zhivar Sourati , Zheng Wang , Marianne Menglin Liu , Yazhe Hu , Mengqing Guo , Sujeeth Bharadwaj , Kyu Han , Tao Sheng , Sujith Ravi , Morteza Dehghani , Dan Roth

Retrieval-Augmented Generation (RAG) has become a widely adopted paradigm for enhancing the reliability of large language models (LLMs). However, RAG systems are sensitive to retrieval strategies that rely on text chunking to construct…

Information Retrieval · Computer Science 2026-03-31 Sun Xu , Tongkai Xu , Baiheng Xie , Li Huang , Qiang Gao , Kunpeng Zhang

Deep Neural Networks (DNNs) have already become a crucial computational approach to revealing the spatial patterns in the human brain; however, there are three major shortcomings in utilizing DNNs to detect the spatial patterns in…

Machine Learning · Computer Science 2022-05-26 Wei Zhang , Yu Bao

We present BioRAGent, an interactive web-based retrieval-augmented generation (RAG) system for biomedical question answering. The system uses large language models (LLMs) for query expansion, snippet extraction, and answer generation while…

Computation and Language · Computer Science 2024-12-18 Samy Ateia , Udo Kruschwitz