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High-entropy alloys (HEAs) and their two-dimensional counterparts (2D-HEAs) have recently attracted attention due to their tunable properties and catalytic potential, yet their chemical complexity makes direct density functional theory…

Materials Science · Physics 2026-03-25 Chun Zhou , Hannu-Pekka Komsa

Machine Learning Interatomic Potentials (MLIPs) are a highly promising alternative to force-fields for molecular dynamics (MD) simulations, offering precise and rapid energy and force calculations. However, Quantum-Mechanical (QM) datasets,…

Machine-learned interatomic potentials (MLIPs) promise to provide near density-functional theory accuracy at a fraction of the computational cost, offering a transformative route toward genuinely predictive chemistry. Yet their predictive…

Materials Science · Physics 2026-03-06 Jeff Armstrong , Adam Jackson , Alin Elena

Active learning for machine-learning interatomic potentials (MLIPs) must address several challenges to be practical: scaling to large candidate pools, leveraging energy-force supervision, and maintaining robustness when candidate pools are…

Machine Learning · Computer Science 2026-05-18 Eszter Varga-Umbrich , Zachary Weller-Davies , Paul Duckworth , Jules Tilly , Olivier Peltre , Shikha Surana

Achieving higher operational voltages, faster charging, and broader temperature ranges for Li-ion batteries necessitates advancements in electrolyte engineering. However, the complexity of optimizing combinations of solvents, salts, and…

Materials Science · Physics 2025-01-10 Suyeon Ju , Jinmu You , Gijin Kim , Yutack Park , Hyungmin An , Seungwu Han

Machine learning interatomic potentials (MLIPs) have substantially advanced atomistic simulations in materials science and chemistry by balancing accuracy and computational efficiency. While leading MLIPs rely on representing atomic…

Materials Science · Physics 2025-05-05 Mingjian Wen , Wei-Fan Huang , Jin Dai , Santosh Adhikari

Machine learning interatomic potentials (MLIPs) have proven to be wildly useful for molecular dynamics simulations, powering countless drug and materials discovery applications. However, MLIPs face two primary bottlenecks preventing them…

Machine Learning · Computer Science 2026-01-30 Kevin Han , Haolin Cong , Bowen Deng , Amir Barati Farimani

We propose a novel approach for constructing training databases for Machine-Learned Interatomic Potential (MLIP) models, specifically designed to capture phase properties across a wide range of conditions. The framework is uniquely…

Materials Science · Physics 2025-12-03 Vincent G. Fletcher , Albert P. Bartók , Livia B. Pártay

Machine learning approaches have recently emerged as powerful tools to probe structure-property relationships in crystals and molecules. Specifically, Machine learning interatomic potentials (MLIP) can accurately reproduce first-principles…

Materials Science · Physics 2024-03-01 Sasaank Bandi , Chao Jiang , Chris A. Marianetti

Recent works have shown the promise of learning pre-trained models for 3D molecular representation. However, existing pre-training models focus predominantly on equilibrium data and largely overlook off-equilibrium conformations. It is…

Chemical Physics · Physics 2023-08-30 Rui Feng , Qi Zhu , Huan Tran , Binghong Chen , Aubrey Toland , Rampi Ramprasad , Chao Zhang

As the atomistic simulations of materials science move from traditional potentials to machine learning interatomic potential (MLIP), the field is entering the second phase focused on discovering and explaining new material phenomena. While…

Materials Science · Physics 2025-01-27 Musanna Galib , Mewael Isiet , Mauricio Ponga

Machine-learning (ML) interatomic potentials (IPs) trained on first-principles datasets are becoming increasingly popular since they promise to treat larger system sizes and longer time scales, compared to the {\em ab initio} techniques…

Materials Science · Physics 2023-09-04 Shuaihua Lu , Luca M. Ghiringhelli , Christian Carbogno , Jinlan Wang , Matthias Scheffler

Machine learning interatomic potentials (MLIPs) evaluate potential energy surfaces orders of magnitude faster while maintaining accuracy comparable to first-principles calculations, and universal MLIPs that cover most of the periodic table…

Chemical Physics · Physics 2026-03-04 Naoya Kuroda , Kenji Ishihara , Tomoya Shiota , Wataru Mizukami

Machine Learning Interatomic Potentials (MLIPs) enable accurate large-scale atomistic simulations, yet improving their expressive capacity efficiently remains challenging. Here we systematically develop Mixture-of-Experts (MoE) and…

Chemical Physics · Physics 2026-03-13 Yuzhi Liu , Duo Zhang , Anyang Peng , Weinan E , Linfeng Zhang , Han Wang

The ability to accurately model interatomic interactions in large-scale systems is fundamental to understanding a wide range of physical and chemical phenomena, from drug-protein binding to the behavior of next-generation materials. While…

Materials Science · Physics 2025-05-26 Taskin Mehereen , Sourav Saha , Intesar Jawad Jaigirdar , Chanwook Park

As with many parts of the natural sciences, machine learning interatomic potentials (MLIPs) are revolutionizing the modeling of molecular crystals. However, challenges remain for the accurate and efficient calculation of sublimation…

Computational Physics · Physics 2025-09-03 Flaviano Della Pia , Benjamin X. Shi , Venkat Kapil , Andrea Zen , Dario Alfè , Angelos Michaelides

Machine-learned interatomic potentials can offer near first-principles accuracy but are computationally expensive, limiting their application to large-scale molecular dynamics simulations. Inspired by quantum mechanics/molecular mechanics…

Materials Science · Physics 2025-11-21 Fraser Birks , Matthew Nutter , Thomas D Swinburne , James R Kermode

The training set of atomic configurations is key to the performance of any Machine Learning Force Field (MLFF) and, as such, the training set selection determines the applicability of the MLFF model for predictive molecular simulations.…

Chemical Physics · Physics 2021-03-24 Gregory Fonseca , Igor Poltavsky , Valentin Vassilev-Galindo , Alexandre Tkatchenko

Interatomic potentials are key to uncovering microscopic structure-property relationships, essential for multiscale simulations and high-throughput experiments. For metallic glasses, their disordered atomic structure makes the development…

In this work, we introduce CHIPS-FF (Computational High-Performance Infrastructure for Predictive Simulation-based Force Fields), a universal, open-source benchmarking platform for machine learning force fields (MLFFs). This platform…

Materials Science · Physics 2025-03-20 Daniel Wines , Kamal Choudhary