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Despite recent advancement in 3D molecule conformation generation driven by diffusion models, its high computational cost in iterative diffusion/denoising process limits its application. In this paper, an equivariant consistency model…

Biomolecules · Quantitative Biology 2023-11-27 Zhiguang Fan , Yuedong Yang , Mingyuan Xu , Hongming Chen

The quality of fetal MRI is significantly affected by unpredictable and substantial fetal motion, leading to the introduction of artifacts even when fast acquisition sequences are employed. The development of 3D real-time fetal pose…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Molin Zhang , Polina Golland , Patricia Ellen Grant , Elfar Adalsteinsson

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

We present MInDI-3D (Medical Inversion by Direct Iteration in 3D), the first 3D conditional diffusion-based model for real-world sparse-view Cone Beam Computed Tomography (CBCT) artefact removal, aiming to reduce imaging radiation exposure.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Daniel Barco , Marc Stadelmann , Martin Oswald , Ivo Herzig , Lukas Lichtensteiger , Pascal Paysan , Igor Peterlik , Michal Walczak , Bjoern Menze , Frank-Peter Schilling

Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Duoyou Chen , Yunqing Chen , Can Zhang , Zhou Wang , Cheng Chen , Ruoxiu Xiao

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Multi-site structural MRI is increasingly used in neuroimaging studies to diversify subject cohorts. However, combining MR images acquired from various sites/centers may introduce site-related non-biological variations. Retrospective image…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Mengqi Wu , Minhui Yu , Shuaiming Jing , Pew-Thian Yap , Zhengwu Zhang , Mingxia Liu

Cone-beam computed tomography (CBCT) is an imaging modality widely used in head and neck diagnostics due to its accessibility and lower radiation dose. However, its relatively long acquisition times make it susceptible to patient motion,…

Daily or weekly cone-beam computed tomography (CBCT) is employed in image-guided radiotherapy (IGRT) for precise patient alignment. However, its clinical utility in quantitative tasks is hindered by severe artifacts and inaccurate Hounsfeld…

Medical Physics · Physics 2026-03-09 Junbo Peng , Huiqiao Xie , Tonghe Wang , Xiangyang Tang , Xiaofeng Yang

Undersampled CT volumes minimize acquisition time and radiation exposure but introduce artifacts degrading image quality and diagnostic utility. Reducing these artifacts is critical for high-quality imaging. We propose a computationally…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Johannes Thalhammer , Tina Dorosti , Sebastian Peterhansl , Daniela Pfeiffer , Franz Pfeiffer , Florian Schaff

Cone-beam computed tomography (CBCT) is widely used in image-guided radiotherapy. Reconstructing CBCTs from limited-angle acquisitions (LA-CBCT) is highly desired for improved imaging efficiency, dose reduction, and better mechanical…

Medical Physics · Physics 2024-04-10 Jiacheng Xie , Hua-Chieh Shao , Yunxiang Li , You Zhang

Low-dose computed tomography (CT) images suffer from noise and artifacts due to photon starvation and electronic noise. Recently, some works have attempted to use diffusion models to address the over-smoothness and training instability…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Hongming Shan

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

The clinical application of cone-beam computed tomography (CBCT) is constrained by the inherent trade-off between radiation exposure and image quality. Ultra-sparse angular sampling, employed to reduce dose, introduces severe undersampling…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Junlin Wang , Jiancheng Fang , Peng Peng , Shaoyu Wang , Qiegen Liu

Diffusion models have significant impact on wide range of generative tasks, especially on image inpainting and restoration. Although the improvements on aiming for decreasing number of function evaluations (NFE), the iterative results are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Mahmut S. Gokmen , Jie Zhang , Ge Wang , Jin Chen , Cody Bumgardner

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Diffusion models have recently enabled state-of-the-art reconstruction of positron emission tomography (PET) images while requiring only image training data. However, domain shift remains a key concern for clinical adoption: priors trained…

Medical Physics · Physics 2025-10-16 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Cone-beam computed tomography (CBCT) using only a few X-ray projection views enables faster scans with lower radiation dose, but the resulting severe under-sampling causes strong artifacts and poor spatial coverage. We address these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Minmin Yang , Huantao Ren , Senem Velipasalar

Light-field microscopy (LFM) enables single-shot capture of multi-angular information from biological samples, supporting real-time volumetric imaging. However, traditional physics-based algorithms often suffer from limited spatial…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Qihong Zhao , Shaokang Yan , Zhimin Qiao , Jinjia Wang , Bo Xiong