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Wounds in the embryo show a remarkable ability to heal quickly without leaving a scar. Previous studies have found that an actomyosin ring ("purse string") forms around the wound perimeter and contracts to close the wound over the course of…

Tissues and Organs · Quantitative Biology 2015-06-15 Matthew A. Wyczalkowski , Victor D. Varner , Larry A. Taber

Wounds in epithelial tissues compromise their vital role in homeostasis. A rapid and efficient wound healing encompasses different mechanisms, which includes the formation of a contractile actin-myosin cable around its edge, known as the…

Soft Condensed Matter · Physics 2024-03-22 R. F. Almada , N. A. M. Araujo , P. Patricio

We develop a model to investigate analytically and numerically the mechanics of wound opening made in a viscoelastic, isotropic, homogeneous, and incompressive thin tissue. This process occurs just immediately after the wound infliction.…

Soft Condensed Matter · Physics 2021-07-14 G. M. Carvalho , N. A. M. Araújo , P. Patrício

Jellyfish cyborgs present a promising avenue for soft robotic systems, leveraging the natural energy-efficiency and adaptability of biological systems. Here we demonstrate a novel approach to predicting and controlling jellyfish locomotion…

Robotics · Computer Science 2024-10-28 Dai Owaki , Max Austin , Shuhei Ikeda , Kazuya Okuizumi , Kohei Nakajima

We propose a model for the structure formation of jellyfish swimming based on active Brownian particles. We address the phenomena of counter-current swimming, avoidance of turbulent flow regions and foraging. We motivate corresponding…

Adaptation and Self-Organizing Systems · Physics 2023-04-21 Erik Gengel , Zafrir Kuplik , Dror Angel , Eyal Heifetz

We present a theory of jellyfish swarm formation and exemplify it with simulations of active Brownian particles. The motivation for our analysis is the phenomenon of jellyfish blooms in the ocean and clustering of jellyfish in tank…

Adaptation and Self-Organizing Systems · Physics 2024-11-26 Erik Gengel , Zafrir Kuplik , Dror Angel , Eyal Heifetz

Skin is the largest organ of many animals. Its protective function against hostile environments and predatorial attack makes high mechanical strength a vital characteristic. Here, we measured the mechanical properties of bass fish skins and…

Biological Physics · Physics 2023-02-01 Emily Zhang , Chi-Huan Tung , Luyi Feng , Yu Ren Zhou

We study theoretically the closure of a wound in a layer of epithelial cells in a living tissue after damage. Our analysis is informed by our recent experiments observing re-epithelialisation in vivo of Drosophila pupae. On time and…

A buckled sheet offers a reservoir of material that can be unfurled at a later time. For sufficiently thin yet stiff materials, this geometric process has a striking mechanical feature: when the slack runs out, the material locks to further…

Soft Condensed Matter · Physics 2025-11-18 Pan Dong , Mengfei He , Nathan C. Keim , Joseph D. Paulsen

We use experiments to study the dynamics of the healing of a blister, a localized bump in a thin elastic layer that is adhered to a soft substrate everywhere except at the bump. We create a blister by gently placing a glass cover slip on a…

Soft Condensed Matter · Physics 2014-02-04 Jonathan E. Longley , L. Mahadevan , Manoj K. Chaudhury

Herein, self-healing small-scale swimmers capable of autonomous propulsion and on-the-fly structural recovery are described. The new strategy instantaneously restores the functionality of the swimmer after it has suffered severe damage.…

Epithelization, the process whereby an epithelium covers a cell-free surface, is not only central to wound healing but also pivotal in embryonic morphogenesis, regeneration, and cancer. In the context of wound healing, the epithelization…

Cell Behavior · Quantitative Biology 2014-02-21 Olivier Cochet-Escartin , Jonas Ranft , Pascal Silberzan , Philippe Marcq

Effective wound repair treatments rely on a clear picture of how cell proliferation and migration are coordinated during tissue restoration. Fibroblasts are key contributors to tissue restoration in the dermis, and modern imaging tools…

Cell Behavior · Quantitative Biology 2026-03-03 Erik Blom , Qiyao Peng , Leah Pomfret , Richard Mort , Stefan Engblom

Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…

Quantitative Methods · Quantitative Biology 2017-10-25 Felix Bäuerle , Mirna Kramar , Karen Alim

The paper studies a curvature flow linked to the physical phenomenon of wound closure. Under the flow we show that a closed, initially convex or close-to-convex curve shrinks to a round point in finite time. We also study the singularity,…

Differential Geometry · Mathematics 2018-02-13 Shuhui He , Glen Wheeler , Valentina-Mira Wheeler

The A901/2 system is a rare case of galaxy cluster interaction, in which two galaxy clusters and two smaller groups are seen in route of collision with each other simultaneously. Within each of the four substructures, several galaxies with…

Tissue fusion eliminates physical voids in a tissue to form a continuous structure and is central to many processes in development and repair. Fusion events in vivo, particularly in embryonic development, often involve the purse-string…

Tissues and Organs · Quantitative Biology 2015-08-12 V. Nier , M. Deforet , G. Duclos , H. G. Yevick , O. Cochet-Escartin , P. Marcq , P. Silberzan

When they are damaged or injured, soft biological tissues are able to self-repair and heal. Mechanics is critical during the healing process, as the damaged extracellular matrix (ECM) tends to be replaced with a new undamaged ECM supporting…

Computational Engineering, Finance, and Science · Computer Science 2021-12-08 Di Zuo , Yiqian He , Stéphane Avril , Haitian Yang , Klaus Hackl

It is well known that galaxies falling into clusters can experience gas stripping due to ram-pressure by the intra-cluster medium (ICM). The most spectacular examples are galaxies with extended tails of optically-bright stripped material…

Microgels are soft colloids that, in virtue of their polymeric nature, can react to external stimuli such as temperature or pH by changing their size. The resulting swelling/deswelling transition can be exploited in fundamental research as…

Soft Condensed Matter · Physics 2019-02-15 Lorenzo Rovigatti , Nicoletta Gnan , Emanuela Zaccarelli
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