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Backpropagation is widely used to train artificial neural networks, but its relationship to synaptic plasticity in the brain is unknown. Some biological models of backpropagation rely on feedback projections that are symmetric with…
Large Language Models (LLMs) are increasingly integrated into software engineering workflows, yet current benchmarks provide only coarse performance summaries that obscure the diverse capabilities and limitations of these models. This paper…
Artificial neural networks trained on large, expert-labelled datasets are considered state-of-the-art for a range of medical image recognition tasks. However, categorically labelled datasets are time-consuming to generate and constrain…
Artificial neural networks are being proposed as models of parts of the brain. The networks are compared to recordings of biological neurons, and good performance in reproducing neural responses is considered to support the model's…
Large Deep Learning models are often compressed before being deployed in a resource-constrained environment. Can we trust the prediction of compressed models just as we trust the prediction of the original large model? Existing work has…
Cognitive science and neuroscience have long faced the challenge of disentangling representations of language from representations of conceptual meaning. As the same problem arises in today's language models (LMs), we investigate the…
Large Language Models (LLMs) are increasingly used in settings where reliable self-assessment is critical. Assessing model reliability has evolved from using probabilistic correctness estimates to, more recently, eliciting verbalized…
The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity…
We propose a Bayesian framework for uncertainty quantification and comparison in brain connectivity graph analysis. Standard graph-based approaches typically rely on point estimates of correlation matrices, overlooking the uncertainty…
Large language models based on self-attention mechanisms have achieved astonishing performances not only in natural language itself, but also in a variety of tasks of different nature. However, regarding processing language, our human brain…
Two recent developments have accelerated progress in image reconstruction from human brain activity: large datasets that offer samples of brain activity in response to many thousands of natural scenes, and the open-sourcing of powerful…
Accurate compensation of brain deformation is a critical challenge for reliable image-guided neurosurgery, as surgical manipulation and tumor resection induce tissue motion that misaligns preoperative planning images with intraoperative…
Understanding how the brain encodes external stimuli and how these stimuli can be decoded from the measured brain activities are long-standing and challenging questions in neuroscience. In this paper, we focus on reconstructing the complex…
Brain connectivity networks, derived from magnetic resonance imaging (MRI), non-invasively quantify the relationship in function, structure, and morphology between two brain regions of interest (ROIs) and give insights into gender-related…
Recent advances in general-purpose AI systems with attention-based transformers offer a potential window into how the neocortex and cerebellum, despite their relatively uniform circuit architectures, give rise to diverse functions and,…
Large language models (LLMs) are increasingly used in human-AI interaction research and practice, yet existing capability and safety benchmarks reveal little about the value priorities these systems express or how those priorities…
A large number of papers have introduced novel machine learning and feature extraction methods for automatic classification of AD. However, they are difficult to reproduce because key components of the validation are often not readily…
Reconstructing visual stimulus (image) only from human brain activity measured with functional Magnetic Resonance Imaging (fMRI) is a significant and meaningful task in Human-AI collaboration. However, the inconsistent distribution and…
In the field of medical image analysis, achieving high accuracy is not enough; ensuring well-calibrated predictions is also crucial. Confidence scores of a deep neural network play a pivotal role in explainability by providing insights into…
Recent advances in MRI have led to the creation of large datasets. With the increase in data volume, it has become difficult to locate previous scans of the same patient within these datasets (a process known as re-identification). To…