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Longitudinal health agents must reason across multi-source trajectories that combine continuous device streams, sparse clinical exams, and episodic life events - yet evaluating them is hard: real-world data cannot be released at scale, and…

Artificial Intelligence · Computer Science 2026-04-06 Chao Li , Cailiang Liu , Ang Gao , Kexin Deng , Shu Zhang , Langping Xu , Xiaotong Shi , Xionghao Ding , Jian Pei , Xun Jiang

Large language models (LLMs) hold great promise for assisting clinical interviews due to their fluent interactive capabilities and extensive medical knowledge. However, the lack of high-quality interview dialogue data and widely accepted…

Computation and Language · Computer Science 2025-04-15 Jing Chen , Zhihua Wei , Wei Zhang , Yingying Hu , Qiong Zhang

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

We introduce NoteChat, a novel cooperative multi-agent framework leveraging Large Language Models (LLMs) to generate patient-physician dialogues. NoteChat embodies the principle that an ensemble of role-specific LLMs, through structured…

Computation and Language · Computer Science 2025-01-30 Junda Wang , Zonghai Yao , Zhichao Yang , Huixue Zhou , Rumeng Li , Xun Wang , Yucheng Xu , Hong Yu

Long-term, open-domain dialogue capabilities are essential for chatbots aiming to recall past interactions and demonstrate emotional intelligence (EI). Yet, most existing research relies on synthetic, LLM-generated data, leaving open…

Computation and Language · Computer Science 2025-02-20 Dong-Ho Lee , Adyasha Maharana , Jay Pujara , Xiang Ren , Francesco Barbieri

Recent large language model (LLM)-driven chat assistant systems have integrated memory components to track user-assistant chat histories, enabling more accurate and personalized responses. However, their long-term memory capabilities in…

Computation and Language · Computer Science 2025-03-06 Di Wu , Hongwei Wang , Wenhao Yu , Yuwei Zhang , Kai-Wei Chang , Dong Yu

Limited access to mental healthcare, extended wait times, and increasing capabilities of Large Language Models (LLMs) has led individuals to turn to LLMs for fulfilling their mental health needs. However, examining the multi-turn mental…

Computation and Language · Computer Science 2025-05-29 Mohit Chandra , Siddharth Sriraman , Harneet Singh Khanuja , Yiqiao Jin , Munmun De Choudhury

Long-term memory is a critical capability for multimodal large language model (MLLM) agents, particularly in conversational settings where information accumulates and evolves over time. However, existing benchmarks either evaluate…

Computation and Language · Computer Science 2026-01-08 Yuanchen Bei , Tianxin Wei , Xuying Ning , Yanjun Zhao , Zhining Liu , Xiao Lin , Yada Zhu , Hendrik Hamann , Jingrui He , Hanghang Tong

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

Long-term memory (LTM) is essential for large language models (LLMs) to achieve autonomous intelligence in complex, evolving environments. Despite increasing efforts in memory-augmented and retrieval-based architectures, there remains a…

Computation and Language · Computer Science 2025-06-17 Luanbo Wan , Weizhi Ma

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

Computation and Language · Computer Science 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

The reasoning capability of large language models (LLMs), defined as their ability to analyze, infer, and make decisions based on input information, is essential for building intelligent task-oriented dialogue systems. However, existing…

Computation and Language · Computer Science 2026-03-02 Yu Zhu , Kai Yang

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Long-term memory systems enable conversational agents based on large language models (LLMs) to retain, retrieve, and apply user-specific information across multi-session interactions. However, existing evaluations mainly assess…

Information Retrieval · Computer Science 2026-05-21 Zhen Tao , Jinxiang Zhao , Peng Liu , Dinghao Xi , Yanfang Chen , Wei Xu , Zhiyu Li

As Large Language Models (LLMs) evolve from static dialogue interfaces to autonomous general agents, effective memory is paramount to ensuring long-term consistency. However, existing benchmarks primarily focus on casual conversation or…

Computation and Language · Computer Science 2026-01-13 Haonan Bian , Zhiyuan Yao , Sen Hu , Zishan Xu , Shaolei Zhang , Yifu Guo , Ziliang Yang , Xueran Han , Huacan Wang , Ronghao Chen

Large Language Models (LLMs) are constrained by their inability to process lengthy inputs, resulting in the loss of critical historical information. To address this limitation, in this paper, we propose the Self-Controlled Memory (SCM)…

Computation and Language · Computer Science 2025-03-19 Bing Wang , Xinnian Liang , Jian Yang , Hui Huang , Shuangzhi Wu , Peihao Wu , Lu Lu , Zejun Ma , Zhoujun Li
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