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Learning the underlying distribution of molecular graphs and generating high-fidelity samples is a fundamental research problem in drug discovery and material science. However, accurately modeling distribution and rapidly generating novel…

Machine Learning · Computer Science 2023-05-24 Han Huang , Leilei Sun , Bowen Du , Weifeng Lv

Using recent advances in generative artificial intelligence (AI) brought by diffusion models, this paper introduces a new synergistic method for spectral computed tomography (CT) reconstruction. Diffusion models define a neural network to…

Denoising diffusion models have driven significant progress in the field of Bayesian inverse problems. Recent approaches use pre-trained diffusion models as priors to solve a wide range of such problems, only leveraging inference-time…

Machine Learning · Statistics 2025-02-06 Yazid Janati , Badr Moufad , Mehdi Abou El Qassime , Alain Durmus , Eric Moulines , Jimmy Olsson

Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Xingjian Tang , Jingwei Guan , Linge Li , Ran Shi , Youmei Zhang , Mengye Lyu , Li Yan

Tomographic image reconstruction is relevant for many medical imaging modalities including X-ray, ultrasound (US) computed tomography (CT) and photoacoustics, for which the access to full angular range tomographic projections might be not…

Image and Video Processing · Electrical Eng. & Systems 2019-06-14 Valery Vishnevskiy , Richard Rau , Orcun Goksel

Diffusion Probabilistic Models (DPMs) are a well-established class of diffusion models for unconditional image generation, while SGMSE+ is a well-established conditional diffusion model for speech enhancement. One of the downsides of…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-11 Bunlong Lay , Timo Gerkmann

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

The presence of noise is an intrinsic problem in acquisition processes for digital images. One way to enhance images is to combine the forward and backward diffusion equations. However, the latter problem is well known to be exponentially…

Numerical Analysis · Mathematics 2023-06-13 Vo Anh Khoa , Mai Thanh Nhat Truong , Imhotep Hogan , Roselyn Williams

We present the development of extended diffraction tomography, a new approach to the solution of the linear seismic waveform inversion problem. This method has several appealing features, such as the use of arbitrary depth-dependent…

Geophysics · Physics 2009-05-05 R. B. Schlottmann

Diffusion models demonstrate remarkable capabilities in capturing complex data distributions and have achieved compelling results in many generative tasks. While they have recently been extended to dense prediction tasks such as depth…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Haorui Ji , Taojun Lin , Hongdong Li

Image restoration aims to recover high-quality images from degraded observations. When the degradation process is known, the recovery problem can be formulated as an inverse problem, and in a Bayesian context, the goal is to sample a clean…

Image and Video Processing · Electrical Eng. & Systems 2025-10-13 Darshan Thaker , Abhishek Goyal , René Vidal

Diffusion models have recently shown promise as powerful generative priors for inverse problems. However, conventional applications require solving the full reverse diffusion process and operating on noisy intermediate states, which poses…

Geophysics · Physics 2025-06-13 Yuke Xie , Hervé Chauris , Nicolas Desassis

Magnetic Resonance Imaging (MRI) is a powerful, non-invasive diagnostic tool; however, its clinical applicability is constrained by prolonged acquisition times. Whilst present deep learning-based approaches have demonstrated potential in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Anurag Malyala , Zhenlin Zhang , Chengyan Wang , Chen Qin

Current end-to-end (E2E) and plug-and-play (PnP) image reconstruction algorithms approximate the maximum a posteriori (MAP) estimate but cannot offer sampling from the posterior distribution, like diffusion models. By contrast, it is…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Jyothi Rikhab Chand , Mathews Jacob

While deep neural networks (NN) significantly advance image compressed sensing (CS) by improving reconstruction quality, the necessity of training current CS NNs from scratch constrains their effectiveness and hampers rapid deployment.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Chen , Zhenyu Zhang , Weiqi Li , Chen Zhao , Jiwen Yu , Shijie Zhao , Jie Chen , Jian Zhang

Existing image restoration methods mostly leverage the posterior distribution of natural images. However, they often assume known degradation and also require supervised training, which restricts their adaptation to complex real…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Ben Fei , Zhaoyang Lyu , Liang Pan , Junzhe Zhang , Weidong Yang , Tianyue Luo , Bo Zhang , Bo Dai

Denoising diffusion probabilistic models (DDPMs) (Ho et al. 2020) have shown impressive results on image and waveform generation in continuous state spaces. Here, we introduce Discrete Denoising Diffusion Probabilistic Models (D3PMs),…

Machine Learning · Computer Science 2023-02-23 Jacob Austin , Daniel D. Johnson , Jonathan Ho , Daniel Tarlow , Rianne van den Berg

Inverse scattering problems, such as those in electromagnetic imaging using phaseless data (PD-ISPs), involve imaging objects using phaseless measurements of wave scattering. Such inverse problems can be highly non-linear and ill-posed…

Signal Processing · Electrical Eng. & Systems 2022-12-07 Samruddhi Deshmukh , Amartansh Dubey , Ross Murch

Deep Gaussian processes (DGPs) enable expressive hierarchical Bayesian modeling but pose substantial challenges for posterior inference, especially over inducing variables. Denoising diffusion variational inference (DDVI) addresses this by…

Machine Learning · Computer Science 2026-02-13 Jian Xu , Qibin Zhao , John Paisley , Delu Zeng

The introduction of diffusion models in anomaly detection has paved the way for more effective and accurate image reconstruction in pathologies. However, the current limitations in controlling noise granularity hinder diffusion models'…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Cosmin I. Bercea , Michael Neumayr , Daniel Rueckert , Julia A. Schnabel