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This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

In Intensive Care Units (ICU), the abundance of multivariate time series presents an opportunity for machine learning (ML) to enhance patient phenotyping. In contrast to previous research focused on electronic health records (EHR), here we…

Machine Learning · Computer Science 2024-10-04 Hollan Haule , Ian Piper , Patricia Jones , Tsz-Yan Milly Lo , Javier Escudero

Magnetic Resonance Imaging (MRI) is widely recognized as the most reliable tool for detecting tumors due to its capability to produce detailed images that reveal their presence. However, the accuracy of diagnosis can be compromised when…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zahid Ullah , Dragan Pamucar , Jihie Kim

Public policy-makers use cost-effectiveness analyses (CEA) to decide which health and social care interventions to provide. Appropriate methods have not been developed for handling missing data in complex settings, such as for CEA that use…

Methodology · Statistics 2012-06-27 Karla Diaz-Ordaz , Michael G. Kenward , Richard Grieve

In recent years, the field of single-cell data analysis has seen a marked advancement in the development of clustering methods. Despite advancements, most of these algorithms still concentrate on analyzing the provided single-cell matrix…

Machine Learning · Computer Science 2023-12-18 Dayu Hu , Ke Liang , Hao Yu , Xinwang Liu

Recent advancements in AI models are structured to retain user interactions, which could inadvertently include sensitive healthcare data. In the healthcare field, particularly when radiologists use AI-driven diagnostic tools hosted on…

With the spread and rapid advancement of black box machine learning models, the field of interpretable machine learning (IML) or explainable artificial intelligence (XAI) has become increasingly important over the last decade. This is…

Antimicrobial Resistance represents a significant challenge in the Intensive Care Unit (ICU), where patients are at heightened risk of Multidrug-Resistant (MDR) infections-pathogens resistant to multiple antimicrobial agents. This study…

The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been…

Early detection of inflammatory arthritis (IA) is critical to efficient and accurate hospital referral triage for timely treatment and preventing the deterioration of the IA disease course, especially under limited healthcare resources. The…

Machine Learning · Computer Science 2024-08-01 Bing Wang , Weizi Li , Anthony Bradlow , Antoni T. Y. Chan , Eghosa Bazuaye

In the past, the development of vaccines and immunotherapeutics relied heavily on trial-and-error experimentation and extensive in vivo testing, often requiring years of pre-clinical and clinical trials. Today, artificial intelligence (AI)…

Artificial Intelligence · Computer Science 2025-06-17 Elhoucine Elfatimi , Yassir Lekbach , Swayam Prakash , Lbachir BenMohamed

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

Human metapneumovirus (hMPV) poses serious risks to pediatric, elderly, and immunocompromised populations. Traditional antibody discovery pipelines require 10-12 months, limiting their applicability for rapid outbreak response. This project…

Quantitative Methods · Quantitative Biology 2025-09-01 Shawnak Shivakumar , Matthew Sandora

Insects are a crucial part of our ecosystem. Sadly, in the past few decades, their numbers have worryingly decreased. In an attempt to gain a better understanding of this process and monitor the insects populations, Deep Learning may offer…

Artificial Intelligence · Computer Science 2022-06-16 Teodor Chiaburu , Felix Biessmann , Frank Hausser

Transparency in Machine Learning (ML), attempts to reveal the working mechanisms of complex models. Transparent ML promises to advance human factors engineering goals of human-centered AI in the target users. From a human-centered design…

Human-Computer Interaction · Computer Science 2022-10-03 Haomin Chen , Catalina Gomez , Chien-Ming Huang , Mathias Unberath

Medical data often exhibit characteristics that make cluster analysis particularly challenging, such as missing values, outliers, and cluster features like skewness. Typically, such data would need to be preprocessed -- by cleaning outliers…

Methodology · Statistics 2025-12-16 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

Motivation: We investigate whether a template-based classification pipeline could be used to identify immunophenotypes in (and thereby classify) a heterogeneous disease with many subtypes. The disease we consider here is Acute Myeloid…

Quantitative Methods · Quantitative Biology 2014-03-26 Ariful Azad , Bartek Rajwa , Alex Pothen

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack…

Machine Learning · Computer Science 2026-04-27 Hojjat Karami , David Atienza , Jean-Philippe Thiran , Anisoara Ionescu
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