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Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Numan Saeed , Shahad Hardan , Muhammad Ridzuan , Nada Saadi , Karthik Nandakumar , Mohammad Yaqub

Geometric data analysis and learning has emerged as a distinct and rapidly developing research area, increasingly recognized for its effectiveness across diverse applications. At the heart of this field lies curvature, a powerful and…

Machine Learning · Computer Science 2025-10-28 Yasharth Yadav , Kelin Xia

We present a Python toolbox for holographic and tomographic X-ray imaging. It comprises a collection of phase retrieval algorithms for the deeply holographic and direct contrast imaging regimes, including non-linear approaches and extended…

Optics · Physics 2025-11-03 Jens Lucht , Paul Meyer , Leon Merten Lohse , Tim Salditt

Mollusk shells are an ideal model system for understanding the morpho-elastic basis of morphological evolution of invertebrates' exoskeletons. During the formation of the shell, the mantle tissue secretes proteins and minerals that calcify…

Quantitative Methods · Quantitative Biology 2019-08-12 Shiva Rudraraju , Derek E. Moulton , Régis Chirat , Alain Goriely , Krishna Garikipati

The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-02 Nima Hatami , Mohsin Bilal , Nasir Rajpoot

Breast cancer exhibits intricate morphological and dynamical heterogeneity across cellular, tissue, and tumor scales, posing challenges to conventional modeling approaches that fail to capture its nonlinear, self-similar, or self-affine,…

Quantitative Methods · Quantitative Biology 2025-11-18 Abhijeet Das , Ramray Bhat , Mohit Kumar Jolly

Deep learning has brought significant advancements to X-ray Computed Tomography (CT) reconstruction, offering solutions to challenges arising from modern imaging technologies. These developments benefit from methods that combine classical…

Machine Learning · Computer Science 2025-11-12 Linda-Sophie Schneider , Yipeng Sun , Chengze Ye , Markus Michen , Andreas Maier

Over the last few years, with the growth of time-series collecting and storing, there has been a great demand for tools and software for temporal data engineering and modeling. This paper presents a generic workflow for time series data…

Computational Engineering, Finance, and Science · Computer Science 2023-10-24 Pejman Farhadi Ghalati , Andreas Schuppert

We tackle the task of geometric image editing, where an object within an image is repositioned, reoriented, or reshaped while preserving overall scene coherence. Previous diffusion-based editing methods often attempt to handle all relevant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Hanshen Zhu , Zhen Zhu , Kaile Zhang , Yiming Gong , Yuliang Liu , Xiang Bai

Regression-based methods have recently shown promising results in reconstructing human meshes from monocular images. By directly mapping raw pixels to model parameters, these methods can produce parametric models in a feed-forward manner…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Hongwen Zhang , Yating Tian , Xinchi Zhou , Wanli Ouyang , Yebin Liu , Limin Wang , Zhenan Sun

Diffusion condensation is a dynamic process that yields a sequence of multiscale data representations that aim to encode meaningful abstractions. It has proven effective for manifold learning, denoising, clustering, and visualization of…

Machine Learning · Computer Science 2023-01-06 Guillaume Huguet , Alexander Tong , Bastian Rieck , Jessie Huang , Manik Kuchroo , Matthew Hirn , Guy Wolf , Smita Krishnaswamy

Antimicrobial peptide discovery is challenged by the astronomical size of peptide space and the relative scarcity of active peptides. Generative models provide continuous latent "maps" of peptide space, but conventionally ignore…

Machine learning models increasingly map biological sequence-fitness landscapes to predict mutational effects. Effective evaluation of these models requires benchmarks curated from empirical data. Despite their impressive scales, existing…

Machine Learning · Computer Science 2025-10-30 Mingyu Huang , Shasha Zhou , Ke Li

Functional data analysis is ubiquitous in most areas of sciences and engineering. Several paradigms are proposed to deal with the dimensionality problem which is inherent to this type of data. Sparseness, penalization, thresholding, among…

Methodology · Statistics 2018-09-05 Rodney V. Fonseca , Aluísio Pinheiro

In this paper, we are concerned with the recovery of the geometric shapes of inhomogeneous inclusions from the associated far field data in electrostatics and acoustic scattering. We present a local resolution analysis and show that the…

Analysis of PDEs · Mathematics 2021-08-17 Habib Ammari , Yat Tin Chow , Hongyu Liu

Accurate polyp segmentation in colonoscopy is essential for early colorectal cancer detection, yet real-world clinical environments pose persistent challenges such as motion blur, specular reflections, and illumination instability. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zhuoyu Wu , Wenhui Ou , Lexi Zhang , Pei-Sze Tan , Dongjun Wu , Junhe Zhao , Wenqi Fang , Raphaël C. -W. Phan

This chapter discusses geometric models of biomolecules and geometric constructs, including the union of ball model, the weigthed Voronoi diagram, the weighted Delaunay triangulation, and the alpha shapes. These geometric constructs enable…

Biomolecules · Quantitative Biology 2015-06-26 Jie Liang

Objective: Alterations of Young's modulus (YM) and Poisson's ratio (PR) in biological tissues are often early indicators of the onset of pathological conditions. Knowledge of these parameters has been proven to be of great clinical…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Md Tauhidul Islam , Songyuan Tang , Chiara Liverani , Ennio Tasciotti , Raffaella Righetti

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

It has been recently shown that neural networks can recover the geometric structure of a face from a single given image. A common denominator of most existing face geometry reconstruction methods is the restriction of the solution space to…

Computer Vision and Pattern Recognition · Computer Science 2017-09-18 Matan Sela , Elad Richardson , Ron Kimmel
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