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Proximal policy optimization (PPO) approximates the trust region update using multiple epochs of clipped SGD. Each epoch may drift further from the natural gradient direction, creating path-dependent noise. To understand this drift, we can…

Machine Learning · Computer Science 2026-03-16 Zelal Su , Mustafaoglu , Sungyoung Lee , Eshan Balachandar , Risto Miikkulainen , Keshav Pingali

The assembly of virus capsids from free coat proteins proceeds by a complicated cascade of association and dissociation steps, the great majority of which cannot be directly experimentally observed. This has made capsid assembly a rich…

Quantitative Methods · Quantitative Biology 2015-07-09 Lu Xie , Gregory R. Smith , Russell Schwartz

Fitting statistical models is computationally challenging when the sample size or the dimension of the dataset is huge. An attractive approach for down-scaling the problem size is to first partition the dataset into subsets and then fit…

Methodology · Statistics 2016-02-15 Xiangyu Wang , David Dunson , Chenlei Leng

Conformal prediction (CP) has attracted broad attention as a simple and flexible framework for uncertainty quantification through prediction sets. In this work, we study how to deploy CP under differential privacy (DP) in a statistically…

Machine Learning · Statistics 2026-04-21 Jiamei Wu , Ce Zhang , Zhipeng Cai , Jingsen Kong , Bei Jiang , Linglong Kong , Lingchen Kong

Autoregressive pre-trained models combined with decoding methods have achieved impressive performance on complex reasoning tasks. While mainstream decoding strategies such as beam search can generate plausible candidate sets, they often…

Machine Learning · Computer Science 2025-09-08 Yuzhu Chen , Yingjie Wang , Shunyu Liu , Yongcheng Jing , Dacheng Tao

Current instance segmentation models achieve high performance on average predictions, but lack principled uncertainty quantification: their outputs are not calibrated, and there is no guarantee that a predicted mask is close to the ground…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Kerri Lu , Dan M. Kluger , Stephen Bates , Sherrie Wang

Preferences within a group of people are not uniform but follow a distribution. While existing alignment methods like Direct Preference Optimization (DPO) attempt to steer models to reflect human preferences, they struggle to capture the…

Computation and Language · Computer Science 2025-05-14 Binwei Yao , Zefan Cai , Yun-Shiuan Chuang , Shanglin Yang , Ming Jiang , Diyi Yang , Junjie Hu

Bayesian optimization (BO) is a popular method for optimizing expensive black-box functions. BO has several well-documented shortcomings, including computational slowdown with longer optimization runs, poor suitability for non-stationary or…

Machine Learning · Computer Science 2024-06-18 E. Visser , C. E. van Daalen , J. C. Schoeman

In Bayesian inference, the most probable explanation (MPE) problem requests a variable instantiation with the highest probability given some evidence. Since a Bayesian network can be encoded as a literal-weighted CNF formula $\varphi$, we…

Logic in Computer Science · Computer Science 2022-05-19 Vu H. N. Phan , Moshe Y. Vardi

Many signal processing algorithms break the target signal into overlapping segments (also called windows, or patches), process them separately, and then stitch them back into place to produce a unified output. At the overlaps, the final…

Signal Processing · Electrical Eng. & Systems 2021-03-15 Ignacio Francisco Ramírez Paulino

In this paper, we adopt conformal prediction, a distribution-free uncertainty quantification (UQ) framework, to obtain confidence prediction intervals with coverage guarantees for Deep Operator Network (DeepONet) regression. Initially, we…

Machine Learning · Computer Science 2024-02-26 Christian Moya , Amirhossein Mollaali , Zecheng Zhang , Lu Lu , Guang Lin

Bayesian optimization is a coherent, ubiquitous approach to decision-making under uncertainty, with applications including multi-arm bandits, active learning, and black-box optimization. Bayesian optimization selects decisions (i.e.…

Machine Learning · Computer Science 2023-12-13 Samuel Stanton , Wesley Maddox , Andrew Gordon Wilson

Decentralized bilevel optimization has garnered significant attention due to its critical role in solving large-scale machine learning problems. However, existing methods often rely on prior knowledge of problem parameters-such as…

Optimization and Control · Mathematics 2025-10-29 Zhiwei Zhai , Wenjing Yan , Ying-Jun Angela Zhang

In demographic literature, forecast uncertainty is often quantified with a statistical model. This model-based approach may potentially suffer from drawbacks, namely model misspecification, selection effect, and lack of finite-sample…

Applications · Statistics 2026-05-29 Han Lin Shang

Bayesian Optimization (BO) is a powerful tool for optimizing complex non-linear systems. However, its performance degrades in high-dimensional problems with tightly coupled parameters and highly asymmetric objective landscapes, where…

Machine Learning · Computer Science 2026-02-12 Aashwin Mishra , Matt Seaberg , Ryan Roussel , Daniel Ratner , Apurva Mehta

Conformal Prediction (CP) is a powerful statistical machine learning tool to construct uncertainty sets with coverage guarantees, which has fueled its extensive adoption in generating prediction regions for decision-making tasks, e.g.,…

Optimization and Control · Mathematics 2025-10-21 Han Wang , Chao Ning

Preferential Bayesian optimization (PBO) learns latent utilities from pairwise comparisons, but most existing methods assume homoscedastic comparison noise. This is inadequate in human-in-the-loop settings, where a user may compare some…

Machine Learning · Computer Science 2026-05-19 Marshal Arijona Sinaga , Julien Martinelli , Samuel Kaski

Conformal prediction offers a distribution-free framework for constructing prediction sets with finite-sample coverage. Yet, efficiently leveraging multiple conformity scores to reduce prediction set size remains a major open challenge.…

Methodology · Statistics 2025-11-18 Congbin Xu , Yue Yu , Haojie Ren , Zhaojun Wang , Changliang Zou

Conformal prediction is an assumption-lean approach to generating distribution-free prediction intervals or sets, for nearly arbitrary predictive models, with guaranteed finite-sample coverage. Conformal methods are an active research topic…

Methodology · Statistics 2024-01-19 Jerzy Wieczorek

In this paper, we present a distributed model predictive control (DMPC) scheme for dynamically decoupled systems which are subject to state constraints, coupling state constraints and input constraints. In the proposed control scheme,…

Systems and Control · Electrical Eng. & Systems 2024-08-17 Adrian Wiltz , Fei Chen , Dimos V. Dimarogonas