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In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures. We introduce Code Like Humans: a new agentic framework for medical coding with large language models. It implements official…

Artificial Intelligence · Computer Science 2025-10-09 Andreas Motzfeldt , Joakim Edin , Casper L. Christensen , Christian Hardmeier , Lars Maaløe , Anna Rogers

Syndrome-based neural decoding (SBND) has emerged as a promising deep learning approach for soft-decision decoding of high-rate, short-length codes. However, this approach still has substantial room for improvement. In this paper, we show…

Information Theory · Computer Science 2026-05-06 Raphaël Le Bidan , Ahmad Ismail , Elsa Dupraz , Charbel Abdel Nour

Availability of diagnostic codes in Electronic Health Records (EHRs) is crucial for patient care as well as reimbursement purposes. However, entering them in the EHR is tedious, and some clinical codes may be overlooked. Given an…

Machine Learning · Computer Science 2023-05-10 Tsvetan R. Yordanov , Ameen Abu-Hanna , Anita CJ Ravelli , Iacopo Vagliano

Objectives: Administrative data is commonly used to inform chronic disease prevalence and support health informatics research. This study assessed the validity of coding comorbidity in the International Classification of Diseases, 10th…

Quantitative Methods · Quantitative Biology 2025-04-02 Jie Pan , Seungwon Lee , Cheligeer Cheligeer , Bing Li , Guosong Wu , Catherine A Eastwood , Yuan Xu , Hude Quan

Recent advances in large language models (LLMs) show potential for clinical applications, such as clinical decision support and trial recommendations. However, the GPT-4 LLM predicts an excessive number of ICD codes for medical coding…

Computation and Language · Computer Science 2023-11-27 Zhichao Yang , Sanjit Singh Batra , Joel Stremmel , Eran Halperin

Code language models have emerged as useful tools for various programming tasks, yet they often struggle when it comes to complex ones. In this paper, we explore the potential of curriculum learning in enhancing the performance of these…

Machine Learning · Computer Science 2024-07-16 Marwa Naïr , Kamel Yamani , Lynda Said Lhadj , Riyadh Baghdadi

Cognitive-Driven Development (CDD) is a coding design technique that aims to reduce the cognitive effort that developers place in understanding a given code unit (e.g., a class). By following CDD design practices, it is expected that the…

Software Engineering · Computer Science 2022-06-23 Leonardo Barbosa , Victor Hugo Santiago , Alberto Luiz Oliveira Tavares de Souza , Gustavo Pinto

Automatic ICD coding is defined as assigning disease codes to electronic medical records (EMRs). Existing methods usually apply label attention with code representations to match related text snippets. Unlike these works that model the…

Computation and Language · Computer Science 2022-04-01 Zheng Yuan , Chuanqi Tan , Songfang Huang

Prediction of medical codes from clinical notes is a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort that human…

Machine Learning · Computer Science 2022-11-01 Byung-Hak Kim

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…

Machine Learning · Computer Science 2024-12-03 Elizabeth Remfry , Rafael Henkin , Michael R Barnes , Aakanksha Naik

Multi-label learning predicts a subset of labels from a given label set for an unseen instance while considering label correlations. A known challenge with multi-label classification is the long-tailed distribution of labels. Many studies…

Machine Learning · Computer Science 2021-12-06 Vithya Yogarajan , Bernhard Pfahringer , Tony Smith , Jacob Montiel

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

Machine Learning · Computer Science 2023-05-10 Guodong Liu

The task of automatically coding the International Classification of Diseases (ICD) in the medical field has been well-established and has received much attention. Automatic coding of the ICD in the medical field has been successful in…

Computation and Language · Computer Science 2026-03-11 Xinxin You , Xien Liu , Xue Yang , Ziyi Wang , Ji Wu

Automated ICD-10 coding from clinical discharge summaries requires models that are both accurate on long-tailed multi-label classification tasks and interpretable to clinicians. Concept Bottleneck Models (CBMs) offer a principled framework…

Machine Learning · Computer Science 2026-05-12 Mohammed Sameer Syed , Xuan Lu

Automatic medical coding has the potential to ease documentation and billing processes. For this task, transparency plays an important role for medical coders and regulatory bodies, which can be achieved using explainability methods.…

Computation and Language · Computer Science 2025-07-03 Katharina Beckh , Elisa Studeny , Sujan Sai Gannamaneni , Dario Antweiler , Stefan Rüping

In-Context Learning (ICL) is an important paradigm for adapting Large Language Models (LLMs) to downstream tasks through a few demonstrations. Despite the great success of ICL, the limitation of the demonstration number may lead to…

Computation and Language · Computer Science 2024-01-10 Caoyun Fan , Jidong Tian , Yitian Li , Hao He , Yaohui Jin

Finding similar patients is a common objective in precision medicine, facilitating treatment outcome assessment and clinical decision support. Choosing widely-available patient features and appropriate mathematical methods for similarity…

Electronic Health Records (EHR) serve as a valuable source of patient information, offering insights into medical histories, treatments, and outcomes. Previous research has developed systems for detecting applicable ICD codes that should be…

Computation and Language · Computer Science 2024-07-09 Mireia Hernandez Caralt , Clarence Boon Liang Ng , Marek Rei

Documentation errors increase healthcare costs and cause unnecessary patient deaths. As the standard language for diagnoses and billing, ICD codes serve as the foundation for medical documentation worldwide. Despite the prevalence of…

Sound · Computer Science 2018-11-28 Albert Haque , Corinna Fukushima

Human coders assign standardized medical codes to clinical documents generated during patients' hospitalization, which is error-prone and labor-intensive. Automated medical coding approaches have been developed using machine learning…

Computation and Language · Computer Science 2022-09-13 Wei Sun , Shaoxiong Ji , Erik Cambria , Pekka Marttinen
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