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Recent advances in language models have enabled framing molecule generation as sequence modeling. However, existing approaches often rely on single-objective reinforcement learning, limiting their applicability to real-world drug design,…

Machine Learning · Computer Science 2025-02-11 Diego Calanzone , Pierluca D'Oro , Pierre-Luc Bacon

Mixture-of-Experts (MoE) has successfully scaled up models while maintaining nearly constant computing costs. By employing a gating network to route input tokens, it selectively activates a subset of expert networks to process the…

Machine Learning · Computer Science 2025-04-22 Mohan Zhang , Pingzhi Li , Jie Peng , Mufan Qiu , Tianlong Chen

Multiple Instance Learning (MIL) is the dominant framework for gigapixel whole-slide image (WSI) classification in computational pathology. However, current MIL aggregators route all instances through a shared pathway, constraining their…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Xin Tian , Jiuliu Lu , Ephraim Tsalik , Bart Wanders , Colleen Knoth , Julian Knight

Sparsely activated Mixture-of-Experts (MoE) models are widely adopted to scale up model capacity without increasing the computation budget. However, vanilla TopK routers are trained in a discontinuous, non-differentiable way, limiting their…

Machine Learning · Computer Science 2025-02-28 Ziteng Wang , Jun Zhu , Jianfei Chen

Mixture-of-Experts (MoE) presents a naturally compatible and scalable framework for multimodal learning, demonstrating strong adaptability across diverse modalities and tasks. Despite its growing success, a comprehensive and systematic…

Machine Learning · Computer Science 2026-05-28 Liangwei Nathan Zheng , Wei Emma Zhang , Olaf Maennel , Lin Yue , Weitong Chen

Sparsely activated Mixture-of-Experts (MoE) models effectively increase the number of parameters while maintaining consistent computational costs per token. However, vanilla MoE models often suffer from limited diversity and specialization…

Machine Learning · Computer Science 2025-07-11 Lei Kang , Jia Li , Mi Tian , Hua Huang

The mixture of Expert (MoE) parallelism is a recent advancement that scales up the model size with constant computational cost. MoE selects different sets of parameters (i.e., experts) for each incoming token, resulting in a…

Machine Learning · Computer Science 2022-12-13 Chaoyang He , Shuai Zheng , Aston Zhang , George Karypis , Trishul Chilimbi , Mahdi Soltanolkotabi , Salman Avestimehr

Class Incremental Learning (CIL) aims to sequentially learn new classes while avoiding catastrophic forgetting of previous knowledge. We propose to use Masked Autoencoders (MAEs) as efficient learners for CIL. MAEs were originally designed…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Jiang-Tian Zhai , Xialei Liu , Andrew D. Bagdanov , Ke Li , Ming-Ming Cheng

In deep learning, mixture-of-experts (MoE) activates one or few experts (sub-networks) on a per-sample or per-token basis, resulting in significant computation reduction. The recently proposed \underline{p}atch-level routing in…

Machine Learning · Computer Science 2023-07-10 Mohammed Nowaz Rabbani Chowdhury , Shuai Zhang , Meng Wang , Sijia Liu , Pin-Yu Chen

Sparse Mixture of Experts (SMoE) enables efficient training of large language models by routing input tokens to a select number of experts. However, training SMoE remains challenging due to the issue of representation collapse. Recent…

Computation and Language · Computer Science 2025-04-01 Giang Do , Hung Le , Truyen Tran

Mixture of Experts (MoE) architectures have become a key approach for scaling large language models, with growing interest in extending them to multimodal tasks. Existing methods to build multimodal MoE models either incur high training…

Computation and Language · Computer Science 2025-06-26 Guoyang Xia , Yifeng Ding , Fengfa Li , Lei Ren , Wei Chen , Fangxiang Feng , Xiaojie Wang

Real-world model deployment across multiple domains requires multimodal models to operate under two complementary regimes: (1) multi-task pretraining, tasks are co-available at design time where related tasks could borrow representational…

Machine Learning · Computer Science 2026-05-12 Xing Han , Shravan Chaudhari , Tanvi Ranade , Rama Chellappa , Suchi Saria

Mixture-of-Experts (MoE) models scale large language models efficiently by sparsely activating experts, but once an expert is selected, it is executed fully. Hence, the trade-off between accuracy and computation in an MoE model typically…

Machine Learning · Computer Science 2026-02-09 Nurbek Tastan , Stefanos Laskaridis , Karthik Nandakumar , Samuel Horvath

Mixtures of Experts (MoEs) have gained prominence in (self-)supervised learning due to their enhanced inference efficiency, adaptability to distributed training, and modularity. Previous research has illustrated that MoEs can significantly…

Machine Learning · Computer Science 2024-06-27 Timon Willi , Johan Obando-Ceron , Jakob Foerster , Karolina Dziugaite , Pablo Samuel Castro

The problem of class incremental learning (CIL) is considered. State-of-the-art approaches use a dynamic architecture based on network expansion (NE), in which a task expert is added per task. While effective from a computational…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Zhiyuan Hu , Yunsheng Li , Jiancheng Lyu , Dashan Gao , Nuno Vasconcelos

Mixture-of-Experts (MoE) models are widely used to scale language models, yet their expert routing behavior and adaptation in a multilingual setting remain underexplored. In this work, we study multilingual routing dynamics during continual…

Computation and Language · Computer Science 2026-05-29 Aditi Khandelwal , Marius Mosbach , Verna Dankers , Siva Reddy , Golnoosh Farnadi

Mixture-of-Experts (MoE) architectures have emerged as a promising approach to scale Large Language Models (LLMs). MoE boosts the efficiency by activating a subset of experts per token. Recent works show that fine-grained experts…

Computation and Language · Computer Science 2025-10-21 Zheyue Tan , Zhiyuan Li , Tao Yuan , Dong Zhou , Weilin Liu , Yueqing Zhuang , Yadong Li , Guowei Niu , Cheng Qin , Zhuyu Yao , Congyi Liu , Haiyang Xu , Boxun Li , Guohao Dai , Bo Zhao , Yu Wang

Mixture-of-Experts (MoE) models achieve efficient scaling through sparse expert activation, but often suffer from suboptimal routing decisions due to distribution shifts in deployment. While existing test-time adaptation methods could…

Computation and Language · Computer Science 2025-10-17 Guinan Su , Yanwu Yang , Li Shen , Lu Yin , Shiwei Liu , Jonas Geiping

Mixture of Experts (MoE) pretraining is more scalable than dense Transformer pretraining, because MoEs learn to route inputs to a sparse set of their feedforward parameters. However, this means that MoEs only receive a sparse backward…

Machine Learning · Computer Science 2025-11-05 Ashwinee Panda , Vatsal Baherwani , Zain Sarwar , Benjamin Therien , Sambit Sahu , Tom Goldstein , Supriyo Chakraborty

The Mixtures-of-Experts (MoE) model is a widespread distributed and integrated learning method for large language models (LLM), which is favored due to its ability to sparsify and expand models efficiently. However, the performance of MoE…

Machine Learning · Computer Science 2024-05-24 Jing Li , Zhijie Sun , Xuan He , Li Zeng , Yi Lin , Entong Li , Binfan Zheng , Rongqian Zhao , Xin Chen