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The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

Populations and Evolution · Quantitative Biology 2020-11-17 Christian Gourieroux , Yang Lu

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

We analyze the susceptible-infected-susceptible model for epidemic spreading in which a fraction of the individuals become immune by vaccination. This process is understood as a dilution by vaccination, which decreases the fraction of the…

Populations and Evolution · Quantitative Biology 2021-11-10 Tânia Tomé , Mário J. de Oliveira

I discuss the so-called SuperSpreader epidemic, for which SARS is the canonical examples (and, perhaps, MERS will be another). I use simulation by an agent-based model as well as the mathematics of multi-type branching-processes to…

Populations and Evolution · Quantitative Biology 2013-08-30 W. David Wick

The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different…

Dynamical Systems · Mathematics 2023-02-01 Shoshana Elgart

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

Populations and Evolution · Quantitative Biology 2010-11-25 Christel Kamp

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki

We analyze a periodically-forced dynamical system inspired by the SIR model with impulsive vaccination. We fully characterize its dynamics according to the proportion $p$ of vaccinated individuals and the time $T$ between doses. If the…

Dynamical Systems · Mathematics 2024-08-02 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

We investigate the spread of diseases, computer viruses or information on complex networks and also immunization strategies to prevent or control the spread. When an entire population cannot be immunized and the effect of immunization is…

Physics and Society · Physics 2011-04-14 Shinji Tanimoto

The problem of targeted network immunization can be defined as the one of finding a subset of nodes in a network to immunize or vaccinate in order to minimize a tradeoff between the cost of vaccination and the final (stationary) expected…

Physics and Society · Physics 2015-07-10 F. Altarelli , A. Braunstein , L. Dall'Asta , J. R. Wakeling , R. Zecchina

We review research papers which use game theory to model the decision making of individuals during an epidemic, attempting to classify the literature and identify the emerging trends in this field. We show that the literature can be…

Populations and Evolution · Quantitative Biology 2020-02-13 Sheryl L. Chang , Mahendra Piraveenan , Philippa Pattison , Mikhail Prokopenko

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

Investigators often evaluate treatment effects by considering settings in which all individuals are assigned a treatment of interest, assuming that an unlimited number of treatment units are available. However, many real-life treatments are…

In this paper, we present a discrete-time networked SEIR model using population flow, its derivation, and assumptions under which this model is well defined. We identify properties of the system's equilibria, namely the healthy states. We…

Systems and Control · Electrical Eng. & Systems 2021-04-16 Brooks Butler , Ciyuan Zhang , Ian Walter , Nishant Nair , Raphael Stern , Philip E. Paré

With significant population fractions in many societies who refuse vaccines, it is important to reconsider how vaccination is incorporated into compartmental epidemiology models. It is still most common to apply the vaccination rate to the…

Populations and Evolution · Quantitative Biology 2026-03-09 Glenn Ledder

Vaccination games in higher-order settings remain underexplored, despite their importance in shaping opinions and collective decisions. Here, we introduce a parsimonious behavioral-epidemiological model to evaluate how peer reinforcement…

Physics and Society · Physics 2026-01-21 Yikang Lu , Ying Wang , Alfonso de Miguel-Arribas , Lei Shi , Yamir Moreno

One long-standing question in epidemiological research is how best to allocate limited amounts of vaccine or similar preventative measures in order to minimize the severity of an epidemic. Much of the literature on the problem of vaccine…

Social and Information Networks · Computer Science 2014-12-02 Krzysztof Drewniak , Joseph Helsing , Armin R. Mikler

For many infectious disease outbreaks, the at-risk population changes their behavior in response to the outbreak severity, causing the transmission dynamics to change in real-time. Behavioral change is often ignored in epidemic modeling…

Methodology · Statistics 2023-10-25 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

Dynamical Systems · Mathematics 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons