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Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Heart disease is the number one killer, and ECGs can assist in the early diagnosis and prevention of deadly outcomes. Accurate ECG interpretation is critical in detecting heart diseases; however, they are often misinterpreted due to a lack…

Machine Learning · Computer Science 2021-10-29 Dharma KC , Chicheng Zhang , Chris Gniady , Parth Sandeep Agarwal , Sushil Sharma

Recent advancements in Large Language Models (LLMs) have drawn increasing attention since the learned embeddings pretrained on large-scale datasets have shown powerful ability in various downstream applications. However, whether the learned…

Computation and Language · Computer Science 2023-02-07 Jielin Qiu , William Han , Jiacheng Zhu , Mengdi Xu , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

A language is constructed of a finite/infinite set of sentences composing of words. Similar to natural languages, Electrocardiogram (ECG) signal, the most common noninvasive tool to study the functionality of the heart and diagnose several…

Signal Processing · Electrical Eng. & Systems 2020-06-17 Sajad Mousavi , Fatemeh Afghah , Fatemeh Khadem , U. Rajendra Acharya

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

Emotion recognition from electroencephalography (EEG) signals remains challenging due to high inter-subject variability, limited labeled data, and the lack of interpretable reasoning in existing approaches. While recent multimodal large…

Machine Learning · Computer Science 2026-01-14 Fei Ma , Han Lin , Yifan Xie , Hongwei Ren , Xiaoyu Shen , Wenbo Ding , Qi Tian

Recent advances in large language models (LLMs) have enabled the development of multimodal medical AI. While models such as MedGemini achieve high accuracy on VQA tasks like USMLE MM, their performance on ECG based tasks remains limited,…

Machine Learning · Computer Science 2026-02-12 Junichiro Takahashi , Masataka Sato , Satoshi Kodeta , Norihiko Takeda

Multimodal large language models (MLLMs) are increasingly being applied in the medical field, particularly in medical imaging. However, developing MLLMs for ECG signals, which are crucial in clinical settings, has been a significant…

Computation and Language · Computer Science 2024-11-25 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

The multi-lead electrocardiogram (ECG) stands as a cornerstone of cardiac diagnosis. Recent strides in electrocardiogram self-supervised learning (eSSL) have brightened prospects for enhancing representation learning without relying on…

Machine Learning · Computer Science 2026-01-01 Tan Pan , Yixuan Sun , Chen Jiang , Qiong Gao , Rui Sun , Xingmeng Zhang , Zhenqi Yang , Limei Han , Yixiu Liang , Yuan Cheng , Kaiyu Guo

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency

Ultrasound interpretation requires both precise lesion localization and holistic clinical reasoning, yet existing methods typically excel at only one of these capabilities: specialized detectors offer strong localization but limited…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Jing Zhang , Wentao Jiang , Tao Huang , Zhiwei Wang , Jianxin Liu , Jian Chen , Ping Ye , Gang Wang , Zengmao Wang , Bo Du , Dacheng Tao

Concept Bottleneck Models (CBMs) are a prominent framework for interpretable AI that map learned visual features to a set of meaningful concepts for task-specific downstream predictions. Their sequential structure enhances transparency by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Mohamed Harmanani , Bining Long , Zhuoxin Guo , Paul F. R. Wilson , Amirhossein Sabour , Minh Nguyen Nhat To , Gabor Fichtinger , Purang Abolmaesumi , Parvin Mousavi

Electrocardiograms (ECGs) are widely used non-invasive measurements of cardiac activity and play a central role in clinical diagnosis. Recent multimodal approaches align ECG signals with clinical reports to incorporate diagnostic semantics,…

The classification of electrocardiogram (ECG) signals is crucial for early detection of arrhythmias and other cardiac conditions. However, despite advances in machine learning, many studies fail to follow standardization protocols, leading…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Guilherme Silva , Pedro Silva , Gladston Moreira , Vander Freitas , Jadson Gertrudes , Eduardo Luz

As a cornerstone of patient care, clinical decision-making significantly influences patient outcomes and can be enhanced by large language models (LLMs). Although LLMs have demonstrated remarkable performance, their application to visual…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Ji Young Byun , Young-Jin Park , Navid Azizan , Rama Chellappa

Cardiovascular disease (CVD) risk stratification remains a major challenge due to its multifactorial nature and limited availability of high-quality labeled datasets. While genomic and electrophysiological data such as SNP variants and ECG…

Quantitative Methods · Quantitative Biology 2025-10-21 Niranjana Arun Menon , Yulong Li , Iqra Farooq , Sara Ahmed , Muhammad Awais , Imran Razzak

Objective: To transform heterogeneous clinical data from electronic health records into clinically meaningful constructed features using data driven method that rely, in part, on temporal relations among data. Materials and Methods: The…

Machine Learning · Computer Science 2017-06-22 Edward Choi , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Contextual clinical reasoning demands robust inference grounded in complex, heterogeneous clinical records. While state-of-the-art fine-tuning, in-context learning (ICL), and retrieval-augmented generation (RAG) enable knowledge exposure,…

Quantitative Methods · Quantitative Biology 2026-04-09 Chuang Zhao , Hongke Zhao , Xiaofang Zhou , Xiaomeng Li

Electrocardiogram (ECG) is widely used in healthcare applications, such as arrhythmia detection and sleep monitoring, making accurate ECG analysis critically essential. Traditional deep learning models for ECG are task-specific, with…

Signal Processing · Electrical Eng. & Systems 2025-10-14 Yu Han , Vittorio Murino , Xiaofeng Liu , Xiang Zhang , Cheng Ding

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti
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