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Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

Neurons and Cognition · Quantitative Biology 2018-10-30 Y. Dabaghian

In this paper we explain the strikingly regular activity of the 'grid' cells in rodent dorsal medial entorhinal cortex (dMEC) and the spatially localized activity of the hippocampal place cells in CA3 and CA1 by assuming that the…

Neurons and Cognition · Quantitative Biology 2008-04-22 Andras Lorincz , Melinda Kiszlinger , Gabor Szirtes

We isolate a geometric mechanism that complements the dynamical suppression of macroscopic interference: In a high-dimensional Hilbert space, almost all state vectors are nearly orthogonal, accommodating an exponentially large reservoir of…

Quantum Physics · Physics 2026-05-06 Karl Svozil

The brain, which uses redundancy and continuous learning to overcome the unreliability of its components, provides a promising path to building computing systems that are robust to the unreliability of their constituent nanodevices. In this…

Emerging Technologies · Computer Science 2018-10-17 Alice Mizrahi , Julie Grollier , Damien Querlioz , M. D. Stiles

Spatial learning across many species is impaired by lesions in the hippocampus, a subcortical brain structure whose cellular composition changes substantially over its 5 to 6 week lifetime from mainly excitatory neurons during development…

Neurons and Cognition · Quantitative Biology 2022-03-28 Sean Knight

Hyperbolic geometry has been successfully applied in modeling brain cortical and subcortical surfaces with general topological structures. However such approaches, similar to other surface based brain morphology analysis methods, usually…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 J. Zhang , Q. Dong , J. Shi , Q. Li , C. M. Stonnington , B. A. Gutman , K. Chen , E. M. Reiman , R. J. Caselli , P. M. Thompson , J. Ye , Y. Wang

Working memory often appears to exceed its basic span by organizing items into compact representations called chunks. Chunking can be learned over time for familiar inputs; however, it can also arise spontaneously for novel stimuli. Such…

Neurons and Cognition · Quantitative Biology 2025-09-19 Weishun Zhong , Mikhail Katkov , Misha Tsodyks

Biological intelligence emerges from substrates that are slow, noisy, and energetically constrained, yet it performs rapid and coherent inference in open-ended environments. Classical computational theories, built around vector-space…

Neurons and Cognition · Quantitative Biology 2026-05-12 Xin Li

We study a model of spiking neurons, with recurrent connections that result from learning a set of spatio-temporal patterns with a spike-timing dependent plasticity rule and a global inhibition. We investigate the ability of the network to…

Neurons and Cognition · Quantitative Biology 2020-04-22 S. Scarpetta , A. de Candia

Vector-HaSH and the Tolman-Eichenbaum Machine (TEM) propose the hippocampal-entorhinal circuit factorizes memory via a grid-cell scaffold for compositional replay. Concurrently, human iEEG shows sharp-wave ripples gate recall and multi-hop…

Neural and Evolutionary Computing · Computer Science 2026-05-25 Hiroyuki Chuma , Kanji Otsuka , Yoichi Sato

Animals must constantly make decisions on the move, such as when choosing among multiple options, or "targets", in space. Recent evidence suggests that this results from a recursive feedback between the (vectorial) neural representation of…

Neurons and Cognition · Quantitative Biology 2025-05-02 Dan Gorbonos , Nir S. Gov , Iain D. Couzin

Forming accurate memory of sequential stimuli is a fundamental function of biological agents. However, the computational mechanism underlying sequential memory in the brain remains unclear. Inspired by neuroscience theories and recent…

Neurons and Cognition · Quantitative Biology 2023-10-27 Mufeng Tang , Helen Barron , Rafal Bogacz

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

Hippocampal CA3 is crucial for the formation of long-term associative memory. It has a heavily recurrent connectivity, and memories are thought to be stored as memory engrams in the CA3. However, despite its importance for memory storage…

Neurons and Cognition · Quantitative Biology 2017-04-26 Yansong Chua , Cheston Tan

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

We propose HiCL, a novel hippocampal-inspired dual-memory continual learning architecture designed to mitigate catastrophic forgetting by using elements inspired by the hippocampal circuitry. Our system encodes inputs through a…

Machine Learning · Computer Science 2026-02-11 Kushal Kapoor , Wyatt Mackey , Yiannis Aloimonos , Xiaomin Lin

The hippocampal-entorhinal complex plays a major role in the organization of memory and thought. The formation of and navigation in cognitive maps of arbitrary mental spaces via place and grid cells can serve as a representation of memories…

Neurons and Cognition · Quantitative Biology 2022-10-31 Paul Stoewer , Achim Schilling , Andreas Maier , Patrick Krauss

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

Neurons and Cognition · Quantitative Biology 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

Sequence learning, prediction and replay have been proposed to constitute the universal computations performed by the neocortex. The Hierarchical Temporal Memory (HTM) algorithm realizes these forms of computation. It learns sequences in an…

Neurons and Cognition · Quantitative Biology 2022-07-21 Younes Bouhadjar , Dirk J. Wouters , Markus Diesmann , Tom Tetzlaff

The Hopfield recurrent neural network is a classical auto-associative model of memory, in which collections of symmetrically-coupled McCulloch-Pitts neurons interact to perform emergent computation. Although previous researchers have…

Adaptation and Self-Organizing Systems · Physics 2015-06-09 Christopher Hillar , Ngoc M. Tran
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