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While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

The latent space of diffusion model mostly still remains unexplored, despite its great success and potential in the field of generative modeling. In fact, the latent space of existing diffusion models are entangled, with a distorted mapping…

Machine Learning · Computer Science 2024-07-17 Jaehoon Hahm , Junho Lee , Sunghyun Kim , Joonseok Lee

Multimodal generative models require a unified approach to handle both discrete data (e.g., text and code) and continuous data (e.g., image, audio, video). In this work, we propose Latent Language Modeling (LatentLM), which seamlessly…

Computation and Language · Computer Science 2024-12-12 Yutao Sun , Hangbo Bao , Wenhui Wang , Zhiliang Peng , Li Dong , Shaohan Huang , Jianyong Wang , Furu Wei

With recent text-to-image models, anyone can generate deceptively realistic images with arbitrary contents, fueling the growing threat of visual disinformation. A key enabler for generating high-resolution images with low computational cost…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Jonas Ricker , Denis Lukovnikov , Asja Fischer

This paper introduces a novel hierarchical autoencoder that maps 3D models into a highly compressed latent space. The hierarchical autoencoder is specifically designed to tackle the challenges arising from large-scale datasets and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Biao Zhang , Peter Wonka

Identifying subtle phenotypic variations in cellular images is critical for advancing biological research and accelerating drug discovery. These variations are often masked by the inherent cellular heterogeneity, making it challenging to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Anis Bourou , Biel Castaño Segade , Thomas Boyer , Valérie Mezger , Auguste Genovesio

Self-supervised representation learning has gained increasing attention for strong generalization ability without relying on paired datasets. However, it has not been explored sufficiently for facial representation. Self-supervised facial…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Ruian He , Zhen Xing , Weimin Tan , Bo Yan

Flow matching is a recent framework to train generative models that exhibits impressive empirical performance while being relatively easier to train compared with diffusion-based models. Despite its advantageous properties, prior methods…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Quan Dao , Hao Phung , Binh Nguyen , Anh Tran

We introduce LlamaGen, a new family of image generation models that apply original ``next-token prediction'' paradigm of large language models to visual generation domain. It is an affirmative answer to whether vanilla autoregressive…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Peize Sun , Yi Jiang , Shoufa Chen , Shilong Zhang , Bingyue Peng , Ping Luo , Zehuan Yuan

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

Biomolecules · Quantitative Biology 2024-05-10 Ian Dunn , David Ryan Koes

Latent space Energy-Based Models (EBMs), also known as energy-based priors, have drawn growing interests in generative modeling. Fueled by its flexibility in the formulation and strong modeling power of the latent space, recent works built…

Machine Learning · Computer Science 2023-10-06 Peiyu Yu , Sirui Xie , Xiaojian Ma , Baoxiong Jia , Bo Pang , Ruiqi Gao , Yixin Zhu , Song-Chun Zhu , Ying Nian Wu

While generative models have seen significant adoption across a wide range of data modalities, including 3D data, a consensus on which model is best suited for which task has yet to be reached. Further, conditional information such as text…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Matthias Humt , Ulrich Hillenbrand , Rudolph Triebel

Data augmentation for domain-specific image classification tasks often struggles to simultaneously address diversity, faithfulness, and label clarity of generated data, leading to suboptimal performance in downstream tasks. While existing…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yixuan Dong , Fang-Yi Su , Jung-Hsien Chiang

Diffusion models have revolutionized image generation, yet several challenges restrict their application to large-image domains, such as digital pathology and satellite imagery. Given that it is infeasible to directly train a model on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Srikar Yellapragada , Alexandros Graikos , Kostas Triaridis , Prateek Prasanna , Rajarsi R. Gupta , Joel Saltz , Dimitris Samaras

Deep Learning has shown great success in reshaping medical imaging, yet it faces numerous challenges hindering widespread application. Issues like catastrophic forgetting and distribution shifts in the continuously evolving data stream…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Mohammad Areeb Qazi , Anees Ur Rehman Hashmi , Santosh Sanjeev , Ibrahim Almakky , Numan Saeed , Camila Gonzalez , Mohammad Yaqub

In this work, we introduce MedIL, a first-of-its-kind autoencoder built for encoding medical images with heterogeneous sizes and resolutions for image generation. Medical images are often large and heterogeneous, where fine details are of…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Tyler Spears , Shen Zhu , Yinzhu Jin , Aman Shrivastava , P. Thomas Fletcher

Classification models that provide human-interpretable explanations enhance clinicians' trust and usability in medical image diagnosis. One research focus is the integration and prediction of pathology-related visual attributes used by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Luisa Gallée , Catharina Silvia Lisson , Christoph Gerhard Lisson , Daniela Drees , Felix Weig , Daniel Vogele , Meinrad Beer , Michael Götz

Continual learning -- the ability to acquire knowledge incrementally without forgetting previous skills -- is fundamental to natural intelligence. While the human brain excels at this, artificial neural networks struggle with "catastrophic…

Machine Learning · Computer Science 2025-09-16 Aoi Otani