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Medical practitioners use survival models to explore and understand the relationships between patients' covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the…

Machine Learning · Statistics 2018-03-09 Jared Katzman , Uri Shaham , Jonathan Bates , Alexander Cloninger , Tingting Jiang , Yuval Kluger

We consider a refinement of differential privacy --- per instance differential privacy (pDP), which captures the privacy of a specific individual with respect to a fixed data set. We show that this is a strict generalization of the standard…

Machine Learning · Statistics 2018-11-15 Yu-Xiang Wang

Survival analysis studies time-modeling techniques for an event of interest occurring for a population. Survival analysis found widespread applications in healthcare, engineering, and social sciences. However, the data needed to train…

Machine Learning · Computer Science 2023-02-22 Alberto Archetti , Eugenio Lomurno , Francesco Lattari , André Martin , Matteo Matteucci

We provide a differentially private algorithm for hypothesis selection. Given samples from an unknown probability distribution $P$ and a set of $m$ probability distributions $\mathcal{H}$, the goal is to output, in a…

Data Structures and Algorithms · Computer Science 2021-01-05 Mark Bun , Gautam Kamath , Thomas Steinke , Zhiwei Steven Wu

This paper focuses on the design and analysis of privacy-preserving techniques for group testing and infection status retrieval. Our work is motivated by the need to provide accurate information on the status of disease spread among a group…

Information Theory · Computer Science 2025-01-24 Mira Gonen , Michael Langberg , Alex Sprintson

Increasingly, medical research is dependent on data collected for non-research purposes, such as electronic health records data (EHR). EHR data and other large databases can be prone to measurement error in key exposures, and unadjusted…

Methodology · Statistics 2020-05-13 Kyunghee Han , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw

The increased use of differential privacy (DP) has allowed the sharing of large amounts of data while reducing the risk of disclosure of sensitive information at the individual level. However, the noise introduced by DP methods makes…

Methodology · Statistics 2026-04-29 Jordan Awan , Xi Chen , Roberto Molinari

Constructing a differentially private (DP) estimator requires deriving the maximum influence of an observation, which can be difficult in the absence of exogenous bounds on the input data or the estimator, especially in high dimensional…

Machine Learning · Statistics 2022-07-27 Ryan Cumings-Menon

Differentially Private algorithms often need to select the best amongst many candidate options. Classical works on this selection problem require that the candidates' goodness, measured as a real-valued score function, does not change by…

Data Structures and Algorithms · Computer Science 2018-11-21 Jingcheng Liu , Kunal Talwar

Differentially-private histograms have emerged as a key tool for location privacy. While past mechanisms have included theoretical & experimental analysis, it has recently been observed that much of the existing literature does not fully…

Databases · Computer Science 2017-02-21 Maryam Fanaeepour , Benjamin I. P. Rubinstein

The task of statistical inference, which includes the building of confidence intervals and tests for parameters and effects of interest to a researcher, is still an open area of investigation in a differentially private (DP) setting.…

Methodology · Statistics 2025-07-17 Ogonnaya Michael Romanus , Younes Boulaguiem , Roberto Molinari

Differential privacy (DP) is widely employed to provide privacy protection for individuals by limiting information leakage from the aggregated data. Two well-known models of DP are the central model and the local model. The former requires…

Cryptography and Security · Computer Science 2024-11-05 Yucheng Fu , Tianhao Wang

The Cox regression, a semi-parametric method of survival analysis, is extremely popular in biomedical applications. The proportional hazards assumption is a key requirement in the Cox model. To accommodate non-proportional hazards, we…

Methodology · Statistics 2022-06-13 Alexander Begun , Elena Kulinskaya

Differentially private data generation techniques have become a promising solution to the data privacy challenge -- it enables sharing of data while complying with rigorous privacy guarantees, which is essential for scientific progress in…

Cryptography and Security · Computer Science 2022-11-09 Dingfan Chen , Raouf Kerkouche , Mario Fritz

Differential privacy is a formal mathematical {stand-ard} for quantifying the degree of that individual privacy in a statistical database is preserved. To guarantee differential privacy, a typical method is adding random noise to the…

Information Theory · Computer Science 2017-03-08 Jianping He , Lin Cai

There has been increasing demand for establishing privacy-preserving methodologies for modern statistics and machine learning. Differential privacy, a mathematical notion from computer science, is a rising tool offering robust privacy…

Methodology · Statistics 2024-05-09 Shurong Lin , Elliot Paquette , Eric D. Kolaczyk

Many commonly used learning algorithms work by iteratively updating an intermediate solution using one or a few data points in each iteration. Analysis of differential privacy for such algorithms often involves ensuring privacy of each step…

Machine Learning · Computer Science 2018-12-12 Vitaly Feldman , Ilya Mironov , Kunal Talwar , Abhradeep Thakurta

Achieving optimal statistical performance while ensuring the privacy of personal data is a challenging yet crucial objective in modern data analysis. However, characterizing the optimality, particularly the minimax lower bound, under…

Statistics Theory · Mathematics 2025-07-15 T. Tony Cai , Yichen Wang , Linjun Zhang

Differentially private learning on real-world data poses challenges for standard machine learning practice: privacy guarantees are difficult to interpret, hyperparameter tuning on private data reduces the privacy budget, and ad-hoc privacy…

Machine Learning · Statistics 2018-12-10 Koen Lennart van der Veen , Ruben Seggers , Peter Bloem , Giorgio Patrini

This paper considers the private release of statistics of disjoint subsets of a dataset, in the setting of data heterogeneity, where users could contribute more than one sample, with different users contributing potentially different…

Cryptography and Security · Computer Science 2025-03-26 V. Arvind Rameshwar , Anshoo Tandon