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Graph-based semi-supervised learning methods, which deal well with the situation of limited labeled data, have shown dominant performance in practical applications. However, the high dimensionality of hyperspectral images (HSI) makes it…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Yanling Miao , Qi Wang , Mulin Chen , Xuelong Li

Accurate hand gesture prediction is crucial for effective upper-limb prosthetic limbs control. As the high flexibility and multiple degrees of freedom exhibited by human hands, there has been a growing interest in integrating deep networks…

Human-Computer Interaction · Computer Science 2026-04-07 Wenjuan Zhong , Yuyang Zhang , Peiwen Fu , Wenxuan Xiong , Mingming Zhang

Representation learning over graph structure data has been widely studied due to its wide application prospects. However, previous methods mainly focus on static graphs while many real-world graphs evolve over time. Modeling such evolution…

Machine Learning · Statistics 2020-09-02 Tijin Yan , Hongwei Zhang , Zirui Li , Yuanqing Xia

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

In order to understand the complexities of cellular biology, researchers are interested in two important metrics: the genetic expression information of cells and their spatial coordinates within a tissue sample. However, state-of-the art…

Machine Learning · Computer Science 2023-11-02 J. Ding , S. N. Zaman , P. Y. Chen , D. Wang

The aim of this paper is to develop a class of spatial transformation models (STM) to spatially model the varying association between imaging measures in a three-dimensional (3D) volume (or 2D surface) and a set of covariates. Our STMs…

Applications · Statistics 2016-07-27 Michelle F. Miranda , Hongtu Zhu , Joseph G. Ibrahim

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

Quantitative Methods · Quantitative Biology 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

With the rapid advances of image editing techniques in recent years, image manipulation detection has attracted considerable attention since the increasing security risks posed by tampered images. To address these challenges, a novel…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Fengsheng Wang , Leyi Wei

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

Spatial Transcriptomics is a novel technology that aligns histology images with spatially resolved gene expression profiles. Although groundbreaking, it struggles with gene capture yielding high corruption in acquired data. Given potential…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Gabriel Mejia , Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Pablo Arbeláez

This paper proposes a new Quantum Spatial Graph Convolutional Neural Network (QSGCNN) model that can directly learn a classification function for graphs of arbitrary sizes. Unlike state-of-the-art Graph Convolutional Neural Network (GCNN)…

Machine Learning · Computer Science 2023-04-04 Lu Bai , Yuhang Jiao , Luca Rossi , Lixin Cui , Jian Cheng , Edwin R. Hancock

Traditional regression models assume stationary relationships between predictors and responses, failing to capture the spatial heterogeneity present in many environmental, epidemiological, and ecological processes. To address this…

Methodology · Statistics 2025-05-27 Justice Akuoko-Frimpong , Edward Shao , Jonathan Ta

Statistical approaches that successfully combine multiple datasets are more powerful, efficient, and scientifically informative than separate analyses. To address variation architectures correctly and comprehensively for high-dimensional…

Methodology · Statistics 2023-09-01 Jiuzhou Wang , Eric F. Lock

We present an approach to denoising spatial transcriptomics images that is particularly effective for uncovering cell identities in the regime of ultra-low sequencing depths, and also allows for interpolation of gene expression. The method…

Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological features. Currently, however, most deep learning-based ST…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Junchao Zhu , Ruining Deng , Tianyuan Yao , Juming Xiong , Chongyu Qu , Junlin Guo , Siqi Lu , Mengmeng Yin , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

The existence of hybrid noise in hyperspectral images (HSIs) severely degrades the data quality, reduces the interpretation accuracy of HSIs, and restricts the subsequent HSIs applications. In this paper, the spatial-spectral gradient…

Computer Vision and Pattern Recognition · Computer Science 2019-10-23 Qiang Zhang , Qiangqiang Yuan , Jie Li , Xinxin Liu , Huanfeng Shen , Liangpei Zhang

In anti-cancer drug development, a major scientific challenge is disentangling the complex relationships between high-dimensional genomics data from patient tumor samples, the corresponding tumor's organ of origin, the drug targets…

Machine Learning · Computer Science 2024-03-29 Omid Bazgir , Zichen Wang , Ji Won Park , Marc Hafner , James Lu

In the realm of skin lesion image classification, the intricate spatial and semantic features pose significant challenges for conventional Convolutional Neural Network (CNN)-based methodologies. These challenges are compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 K. P. Santoso , R. V. H. Ginardi , R. A. Sastrowardoyo , F. A. Madany

Spatially Resolved Transcriptomics (SRT) is a cutting-edge technique that captures the spatial context of cells within tissues, enabling the study of complex biological networks. Recent graph-based methods leverage both gene expression and…

Machine Learning · Computer Science 2025-06-24 Yunhak Oh , Junseok Lee , Yeongmin Kim , Sangwoo Seo , Namkyeong Lee , Chanyoung Park

Although spatio-temporal graph neural networks have achieved great empirical success in handling multiple correlated time series, they may be impractical in some real-world scenarios due to a lack of sufficient high-quality training data.…

Signal Processing · Electrical Eng. & Systems 2021-02-10 Chao Pan , Siheng Chen , Antonio Ortega