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Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in both crystal and AlphaFold-predicted structures poses…

Biomolecules · Quantitative Biology 2025-03-25 Zhongyue Zhang , Runze Ma , Yanjie Huang , Shuangjia Zheng

Models operating on dynamic physiologic signals must distinguish benign, label-preserving variability from true concept change. Existing concept-drift frameworks are largely distributional and provide no principled guidance on how much a…

Machine Learning · Computer Science 2026-03-02 Timothy Oladunni , Blessing Ojeme , Kyndal Maclin , Clyde Baidoo

Recent methods for molecular generation face a trade-off: they either enforce strict equivariance with costly architectures or relax it to gain scalability and flexibility. We propose a frame-based diffusion paradigm that achieves…

Machine Learning · Computer Science 2025-10-07 Mohan Guo , Cong Liu , Patrick Forré

In the high field region at the head of a discharge streamer, the electron energy distribution develops a long tail. In negative streamers, these electrons can run away and contribute to energetic processes such as terrestrial gamma-ray and…

Plasma Physics · Physics 2012-09-17 Chao Li , Jannis Teunissen , Margreet Nool , Willem Hundsdorfer , Ute Ebert

Understanding demand-side energy behaviour is critical for making efficiency responses for energy demand management. We worked closely with energy experts and identified the key elements of the energy demand problem including temporal and…

Human-Computer Interaction · Computer Science 2020-06-18 Junqi Wu , Zhibin Niu , Jing Wu , Xiufeng Liu , Jiawan Zhang

We present the AM$^3$ ("Astrophysical Multi-Messenger Modeling") software. AM$^3$ is a documented open source software that efficiently solves the coupled integro-differential equations describing the temporal evolution of the spectral…

In this paper we present a new thin-wall eddy current modeling code, ThinCurr, for studying inductively-coupled currents in 3D conducting structures -- with primary application focused on the interaction between currents flowing in coils,…

Molecular dynamics (MD) simulations play a crucial role in resolving the underlying conformational dynamics of molecular systems. However, their capability to correctly reproduce and predict dynamics in agreement with experiments is limited…

Chemical Physics · Physics 2025-05-19 Ivan Gilardoni , Valerio Piomponi , Thorben Fröhlking , Giovanni Bussi

Edge plasma turbulence is critical to the performance of magnetic confinement fusion devices. Towards better understanding edge turbulence in both theory and experiment, a custom-built physics-informed deep learning framework constrained by…

Plasma Physics · Physics 2022-05-17 Abhilash Mathews

In recent years, Denoising Diffusion Probabilistic Models (DDPMs) have demonstrated exceptional performance in various 2D generative tasks. Following this success, DDPMs have been extended to 3D shape generation, surpassing previous…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Cristian Sbrolli , Paolo Cudrano , Matteo Frosi , Matteo Matteucci

We discuss an effective field theory (EFT) approach to the computation of fluctuation-induced interactions between particles bound to a thermally fluctuating fluid surface controlled by surface tension. By describing particles as points,…

Soft Condensed Matter · Physics 2015-06-12 Cem Yolcu , Ira Z. Rothstein , Markus Deserno

This paper outlines a numerical algorithm that could be used for simulating full 3D dynamics of magnetic fluid droplet shapes in external magnetic fields, by solving boundary integral equations. The algorithm works with arbitrary droplet…

Fluid Dynamics · Physics 2022-03-18 Aigars Langins , Andris P. Stikuts , Andrejs Cēbers

We present 2D and 3D Particle-in-Cell simulations of driven collisionless magnetic reconnection triggered by the compression and merger of two Lundquist-type force-free flux tubes in a strongly magnetized pair plasma, with a focus on…

Plasma Physics · Physics 2026-04-29 Camille Granier , Fabio Bacchini , Daniel Groselj , Lorenzo Sironi

Modeling 3D dynamics is a fundamental problem in multi-body systems across scientific and engineering domains and has important practical implications in object trajectory prediction and simulation. While recent GNN-based approaches have…

Machine Learning · Computer Science 2026-05-12 Kai Yang , Yuqi Huang , Junheng Tao , Wanyu Wang , Qitian Wu

Computational fluid dynamics (CFD) drives progress in numerous scientific and engineering fields, yet high-fidelity simulations remain computationally prohibitive. While machine learning approaches offer computing acceleration, they…

Fluid Dynamics · Physics 2025-08-12 Rui Zhang , Qi Meng , Han Wan , Yang Liu , Zhi-Ming Ma , Hao Sun

The aim of the study is to analyze the stability of the Energetic Particle Modes (EPM) and Alfven Eigenmodes (AE) in Helitron J and LHD plasma if the electron cyclotron current drive (ECCD) is applied. The analysis is performed using the…

Plasma Physics · Physics 2020-10-09 J. Varela , K. Nagasaki , K. Nagaoka , S. Yamamoto , K. Y. Watanabe , D. A. Spong , L. Garcia , A. Cappa , A. Azegami

This paper presents a novel methodology for fast simulation and analysis of transient heat transfer. The proposed methodology is suitable for real-time applications owing to (i) establishing the solution method from the viewpoint of…

Computational Engineering, Finance, and Science · Computer Science 2021-12-30 Jinao Zhang , Sunita Chauhan

Edge Digital Twins (EDTs) are crucial for monitoring and control of Power Electronics Systems (PES). However, existing modeling approaches struggle to consistently capture continuously evolving hybrid dynamics that are inherent in PES,…

Machine Learning · Computer Science 2025-08-06 Jialin Zheng , Haoyu Wang , Yangbin Zeng , Di Mou , Xin Zhang , Hong Li , Sergio Vazquez , Leopoldo G. Franquelo

Particle-in-Cell Monte Carlo simulations on large-scale systems play a fundamental role in understanding the complexities of plasma dynamics in fusion devices. Efficient handling and analysis of vast datasets are essential for advancing…

End-to-end perception and trajectory prediction from raw sensor data is one of the key capabilities for autonomous driving. Modular pipelines restrict information flow and can amplify upstream errors. Recent query-based, fully…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Matej Halinkovic , Nina Masarykova , Alexey Vinel , Marek Galinski