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The present habilitation thesis in theoretical biological physics addresses two central dynamical processes in cells and organisms: (i) active motility and motility control and (ii) self-organized pattern formation. The unifying theme is…

Cell Behavior · Quantitative Biology 2018-03-21 Benjamin M. Friedrich

We study the pattern formation in a lattice of coupled phase oscillators with quenched disorder. In the synchronized regime concentric waves can arise, which are induced and increase in regularity by the disorder of the system. Maximal…

Disordered Systems and Neural Networks · Physics 2009-11-11 Bernd Blasius , Ralf Toenjes

We study theoretically the behavior of a class of hydrodynamic dipoles. This study is motivated by recent experiments on synthetic and biological swimmers in microfluidic \textit{Hele-Shaw} type geometries. Under such confinement, a…

Fluid Dynamics · Physics 2015-09-30 Eva Kanso , Alan Tsang

This paper investigates synchronization phenomena in networks of coupled oscillators governed by three-time-scale dynamical systems exhibiting canard dynamics. A mathematical framework has been developed to analyze the synchronization of…

Dynamical Systems · Mathematics 2025-05-28 Navojit Dhali Pallab

A wide spectrum of Peritrichous bacteria undergo considerable physiological changes when they are inoculated onto nutrition-rich surfaces and exhibit a rapid and collective migration denoted as swarming. Thereby, the length of such swarmer…

Biological Physics · Physics 2016-10-25 Thomas Eisenstecken , Jinglei Hu , Roland G. Winkler

The eukaryotic flagellum beats with apparently unfailing periodicity, yet responds rapidly to stimuli. Like the human heartbeat, flagellar oscillations are now known to be noisy. Using the alga \textit{C. reinhardtii}, we explore three…

Soft Condensed Matter · Physics 2014-12-03 Kirsty Y. Wan , Raymond E. Goldstein

All interesting and fascinating collective properties of a complex system arise from the intricate way in which its components interact. Various systems in physics, biology, social sciences and engineering have been successfully modelled as…

Adaptation and Self-Organizing Systems · Physics 2021-04-23 L. V. Gambuzza , F. Di Patti , L. Gallo , S. Lepri , M. Romance , R. Criado , M. Frasca , V. Latora , S. Boccaletti

Unlike Newtonian fluids, viscoelastic fluids may break time-reversal symmetry at low Reynolds numbers resulting in elastic turbulence. Furthermore, under some conditions, instead of the chaotic turbulence, large-scale regular waves form, as…

Fluid Dynamics · Physics 2023-01-19 Jason P. Beech , Oskar E. Ström , Jonas O. Tegenfeldt

Cilia and flagella exhibit regular bending waves that perform mechanical work on the surrounding fluid, to propel cellular swimmers and pump fluids inside organisms. Here, we quantify a force-velocity relationship of the beating flagellum,…

Cell Behavior · Quantitative Biology 2016-12-21 Gary S. Klindt , Christian Ruloff , Christian Wanger , Benjamin M. Friedrich

Most motile bacteria swim in viscous fluids by rotating multiple helical flagellar filaments. These semi-rigid filaments repeatedly join ('bundle') and separate ('unbundle'), resulting in a two-gait random walk-like motion of the cell. In…

Fluid Dynamics · Physics 2020-11-18 Alexander Chamolly , Eric Lauga

We propose a methodology to analyze synchronization in an ensemble of diffusively coupled multistable systems. First, we study how two bidirectionally coupled multistable oscillators synchronize and demonstrate the high complexity of the…

Chaotic Dynamics · Physics 2015-06-23 R. Sevilla-Escoboza , J. M. Buldú , A. N. Pisarchik , S. Boccaletti , R. Gutiérrez

Peritrichous bacteria such as Escherichia coli swim in viscous fluids by forming a helical bundle of flagellar filaments. The filaments are spatially distributed around the cell body to which they are connected via a flexible hook. To…

Biological Physics · Physics 2019-06-19 Kenta Ishimoto , Eric Lauga

At high concentration, free swimming nematodes known as vinegar eels ({\it Turbatrix aceti}), collectively exhibit metachronal waves near a boundary. We find that the frequency of the collective traveling wave is lower than that of the…

Soft Condensed Matter · Physics 2023-02-07 A. C. Quillen , A. Peshkov , Esteban Wright , Sonia McGaffigan

We present our study on the emergent states of two interacting nonlinear systems with differing dynamical time scales. We find that the inability of the interacting systems to fall in step leads to difference in phase as well as change in…

Chaotic Dynamics · Physics 2016-02-09 Kajari Gupta , G. Ambika

Bacteria exist in a free-swimming state or in a sessile biofilm state. The transition from free-swimming to sessile mode is characterized by changes in gene expression which alter, among others,the mechanics of flagellar motility. In this…

Fluid Dynamics · Physics 2014-05-07 Alan Cheng Hou Tsang , Eva Kanso

Simulations of over $10^3$ hydrodynamically coupled solid spheres are performed to investigate collective motion of linear trains and regular square arrays of particles suspended in a fluid bounded by two parallel walls. Our novel…

Soft Condensed Matter · Physics 2008-04-29 M. Baron , J. Blawzdziewicz , E. Wajnryb

We employ a model system, called rowers, as a generic physical framework to define the problem of the coordinated motion of cilia (the metachronal wave) as a far from equilibrium process. Rowers are active (two-state) oscillators…

Biological Physics · Physics 2013-05-29 M. Cosentino Lagomarsino , P. Jona , B. Bassetti

Results are presented from numerical modeling of the effect of the inhomogeneity of the ion background on the complicated spatiotemporal dynamics of an electron beam with a virtual cathode in plane geometry. The possibility is demonstrated…

Plasma Physics · Physics 2015-06-26 A. A. Koronovskii , A. E. Hramov

In a recent letter (Friedrich et al., Phys. Rev. Lett. 109:138102, 2012), a minimal model swimmer was proposed that propels itself at low Reynolds numbers by a revolving motion of a pair of spheres. The motion of the two spheres can…

Cell Behavior · Quantitative Biology 2015-06-12 Katja Polotzek , Benjamin M. Friedrich

Synchronization is a ubiquitous phenomenon in nature and we propose its new perspective in ultrafast dynamics in interacting electron systems. In particular, using graphene irradiated by an intense bi-circular pulse laser as a prototypical…

Strongly Correlated Electrons · Physics 2019-10-02 Tanay Nag , Robert-Jan Slager , Takuya Higuchi , Takashi Oka