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Serving generative inference of the large language model is a crucial component of contemporary AI applications. This paper focuses on deploying such services in a heterogeneous and cross-datacenter setting to mitigate the substantial…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-28 Youhe Jiang , Ran Yan , Xiaozhe Yao , Yang Zhou , Beidi Chen , Binhang Yuan

We study offline scheduling for large language model (LLM) serving under a fixed KV-cache memory budget, where requests have heterogeneous prompt (prefill) and response (decode) lengths. Prompt tokens determine initial KV usage, and each…

Optimization and Control · Mathematics 2026-02-11 Meixuan Wang , Yinyu Ye , Zijie Zhou

Large Language Model (LLM)-based agents exhibit significant potential across various domains, operating as interactive systems that process environmental observations to generate executable actions for target tasks. The effectiveness of…

Computation and Language · Computer Science 2024-08-20 Mengkang Hu , Tianxing Chen , Qiguang Chen , Yao Mu , Wenqi Shao , Ping Luo

Nowadays, many companies possess various types of AI accelerators, forming heterogeneous clusters. Efficiently leveraging these clusters for high-throughput large language model (LLM) inference services can significantly reduce costs and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-23 Yi Xiong , Jinqi Huang , Wenjie Huang , Xuebing Yu , Entong Li , Zhixiong Ning , Jinhua Zhou , Li Zeng , Xin Chen

In latency-sensitive applications, efficient task scheduling is crucial for maintaining Quality of Service (QoS) while meeting strict timing constraints. This paper addresses the challenge of scheduling periodic tasks structured as directed…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-17 Ashutosh Shankar , Astha Kumari

The rapid development of large language model (LLM)-based agents has unlocked new possibilities for autonomous multi-turn reasoning and tool-augmented decision-making. However, their real-world deployment is hindered by severe…

Large Language Models (LLMs) are increasingly being deployed as intelligent agents. Their multi-stage workflows, which alternate between local computation and calls to external network services like Web APIs, introduce a mismatch in their…

Computation and Language · Computer Science 2025-12-17 Hongqiu Ni , Jiabao Zhang , Guopeng Li , Zilong Wang , Ruiqi Wu , Chi Zhang , Haisheng Tan

This paper introduces Helix, a distributed system for high-throughput, low-latency large language model (LLM) serving in heterogeneous GPU clusters. The key idea behind Helix is to formulate inference computation of LLMs over heterogeneous…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-07 Yixuan Mei , Yonghao Zhuang , Xupeng Miao , Juncheng Yang , Zhihao Jia , Rashmi Vinayak

Agentic AI has significantly extended the capabilities of large language models (LLMs) by enabling complex reasoning and tool use. However, most existing frameworks are tailored to domains such as mathematics, coding, or web automation, and…

Artificial Intelligence · Computer Science 2025-10-15 Md Hasebul Hasan , Mahir Labib Dihan , Tanzima Hashem , Mohammed Eunus Ali , Md Rizwan Parvez

The advent of always-on personal AI assistants, enabled by all-day wearable devices such as smart glasses, demands a new level of contextual understanding, one that goes beyond short, isolated events to encompass the continuous,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Aniket Rege , Arka Sadhu , Yuliang Li , Kejie Li , Ramya Korlakai Vinayak , Yuning Chai , Yong Jae Lee , Hyo Jin Kim

Large-scale single-cell and Perturb-seq investigations routinely involve clustering cells and subsequently annotating each cluster with Gene-Ontology (GO) terms to elucidate the underlying biological programs. However, both stages,…

The integration of generative AI models, particularly large language models (LLMs), into real-time multi-model AI applications such as video conferencing and gaming is giving rise to a new class of workloads: real-time generative AI…

Machine Learning · Computer Science 2025-07-22 Rachid Karami , Rajeev Patwari , Hyoukjun Kwon , Ashish Sirasao

This paper addresses emerging system-level challenges in heterogeneous retrieval-augmented generation (RAG) serving, where complex multi-stage workflows and diverse request patterns complicate efficient execution. We present HedraRAG, a…

Databases · Computer Science 2025-07-15 Zhengding Hu , Vibha Murthy , Zaifeng Pan , Wanlu Li , Xiaoyi Fang , Yufei Ding , Yuke Wang

Agentic workflows carry out complex tasks by orchestrating multiple large language models (LLMs) and tools. Serving such workflows at a target throughput with low latency is challenging because they can be defined using arbitrary agentic…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-17 Marcel Wagenländer , Otto White , Britannio Jarrett , Pedro Silvestre , Yanda Tao , Guo Li , Huanzhou Zhu , Llúis Vilanova , Peter Pietzuch

Large Language Model (LLM) workloads have distinct prefill and decode phases with different compute and memory requirements which should ideally be accounted for when scheduling input queries across different LLM instances in a cluster.…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-08 Kunal Jain , Anjaly Parayil , Ankur Mallick , Esha Choukse , Xiaoting Qin , Jue Zhang , Íñigo Goiri , Rujia Wang , Chetan Bansal , Victor Rühle , Anoop Kulkarni , Steve Kofsky , Saravan Rajmohan

KV cache management is essential for efficient LLM inference. To maximize utilization, existing inference engines evict finished requests' KV cache if new requests are waiting. This policy breaks for agentic workloads, which interleave LLM…

Operating Systems · Computer Science 2026-05-27 Hanchen Li , Runyuan He , Qiuyang Mang , Qizheng Zhang , Huanzhi Mao , Xiaokun Chen , Hangrui Zhou , Alvin Cheung , Joseph Gonzalez , Ion Stoica

LLM-based coding agents can generate functionally correct GPU kernels, yet their performance remains far below hand-optimized libraries on critical computations such as matrix multiplication, attention, and Mixture-of-Experts (MoE). Peak…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-22 Haohui Mai , Xiaoyan Guo , Xiangyun Ding , Daifeng Li , Qiuchu Yu , Chenzhun Guo , Cong Wang , Jiacheng Zhao , Christos Kozyrakis , Binhang Yuan

LAPS identifies and disaggregates requests with different prompt lengths in LLM serving to reduce TTFT latency. While recent systems have decoupled the prefill and decode stages to improve throughput, they still rely on unified scheduling…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-29 Jianshu She , Zonghang Li , Hongchao Du , Shangyu Wu , Wenhao Zheng , Eric Xing , Zhengzhong Liu , Huaxiu Yao , Jason Xue , Qirong Ho

LLM-based coding agents are increasingly common but still face challenges in context management, latency, reliability, reproducibility, and scalability. We present Agint, an agentic graph compiler, interpreter, and runtime that…

Software Engineering · Computer Science 2025-11-26 Abhi Chivukula , Jay Somasundaram , Vijay Somasundaram

Drug discovery is a complex, multi-step pipeline that remains heavily dependent on manual, experience-driven operations; meanwhile, existing customized artificial intelligence tools are fragmented across web applications, desktop software,…

Biomolecules · Quantitative Biology 2026-03-03 Qihua Pan , Dong Xu , Qianwei Yang , Jenna Xinyi Yao , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji