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Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

Electrocardiogram (ECG) monitoring is one of the most powerful technique of cardiovascular disease (CVD) early identification, and the introduction of intelligent wearable ECG devices has enabled daily monitoring. However, due to the need…

Signal Processing · Electrical Eng. & Systems 2024-03-08 Hongxiang Gao , Xingyao Wang , Zhenghua Chen , Min Wu , Jianqing Li , Chengyu Liu

The electrocardiogram (ECG) is the gold standard for non-invasive diagnosis of cardiac pathologies and is a fundamental pillar of cardiovascular medicine. Recent progress in deep learning has led to the development of robust automated…

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

Remote photoplethysmography (rPPG) enables non-contact physiological measurement but remains highly susceptible to illumination changes, motion artifacts, and limited temporal modeling. Large Language Models (LLMs) excel at capturing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yiping Xie , Bo Zhao , Mingtong Dai , Jian-Ping Zhou , Yue Sun , Tao Tan , Weicheng Xie , Linlin Shen , Zitong Yu

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Hung Manh Pham , Jialu Tang , Aaqib Saeed , Dong Ma

Photoplethysmography (PPG) signals, typically acquired from wearable devices, hold significant potential for continuous fitness-health monitoring. In particular, heart conditions that manifest in rare and subtle deviating heart patterns may…

Machine Learning · Computer Science 2023-07-14 Ramin Ghorbani , Marcel J. T. Reinders , David M. J. Tax

Deep learning approaches for heart-sound (PCG) segmentation built on time-frequency features can be accurate but often rely on large expert-labeled datasets, limiting robustness and deployment. We present TopSeg, a topological…

Sound · Computer Science 2026-02-02 Peihong Zhang , Zhixin Li , Yuxuan Liu , Rui Sang , Yiqiang Cai , Yizhou Tan , Shengchen Li

Photoplethsmography (PPG)-based individual identification aiming at recognizing humans via intrinsic cardiovascular activities has raised extensive attention due to its high security and resistance to mimicry. However, this kind of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Riling Wei , Hanjie Chen , Kelu Yao , Chuanguang Yang , Jun Wang , Chao Li

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Heart rate (HR) estimation from photoplethysmography (PPG) signals is a key feature of modern wearable devices for health and wellness monitoring. While deep learning models show promise, their performance relies on the availability of…

Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals…

Machine Learning · Computer Science 2020-10-21 Dongdong Zhang , Xiaohui Yuan , Ping Zhang

Photoplethysmography (PPG) is a widely used non-invasive sensing modality for continuous cardiovascular and physiological monitoring across clinical, laboratory, and wearable settings. While existing PPG datasets support a broad range of…

Computation and Language · Computer Science 2026-05-08 Hung Manh Pham , Jinyang Wu , Xiao Ma , Yiming Zhang , Yixin Xu , Aaqib Saeed , Bin Zhu , Zhou Pan , Dong Ma

Electrocardiography (ECG) serves as an indispensable diagnostic tool in clinical practice, yet existing multimodal large language models (MLLMs) remain unreliable for ECG interpretation, often producing plausible but clinically incorrect…

Computation and Language · Computer Science 2026-05-26 Jiarui Jin , Haoyu Wang , Xingliang Wu , Xiaocheng Fang , Xiang Lan , Zihan Wang , Deyun Zhang , Bo Liu , Yingying Zhang , Xian Wu , Hongyan Li , Shenda Hong

Large-scale models pre-trained on Electroencephalography (EEG) have shown promise in clinical applications such as neurological disorder detection. However, the practical deployment of EEG-based large-scale models faces critical challenges…

Machine Learning · Computer Science 2025-08-12 Guanghao Jin , Yuan Liang , Yihan Ma , Jingpei Wu , Guoyang Liu

The Ear-ECG provides a continuous Lead I electrocardiogram (ECG) by measuring the potential difference related to heart activity using electrodes that can be embedded within earphones. The significant increase in wearability and comfort…

Signal Processing · Electrical Eng. & Systems 2023-05-24 Harry J. Davies , Ghena Hammour , Marek Zylinski , Amir Nassibi , Danilo P. Mandic

Accurate extraction of heart rate from photoplethysmography (PPG) signals remains challenging due to motion artifacts and signal degradation. Although deep learning methods trained as a data-driven inference problem offer promising…

Signal Processing · Electrical Eng. & Systems 2024-10-21 Christodoulos Kechris , Jonathan Dan , Jose Miranda , David Atienza

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam
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