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Accelerated materials discovery is an urgent demand to drive advancements in fields such as energy conversion, storage, and catalysis. Property-directed generative design has emerged as a transformative approach for rapidly discovering new…

A comprehensive understanding of heat transport is essential for optimizing various mechanical and engineering applications, including 3D printing. Recent advances in machine learning, combined with physics-based models, have enabled a…

Machine Learning · Computer Science 2026-03-17 Benjamin Uhrich , Tim Häntschel , Erhard Rahm

Precise pose estimation of optical microrobots is essential for enabling high-precision object tracking and autonomous biological studies. However, current methods rely heavily on large, high-quality microscope image datasets, which are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zongcai Tan , Lan Wei , Dandan Zhang

Rapid urbanization demands accurate and efficient monitoring of turbulent wind patterns to support air quality, climate resilience and infrastructure design. Traditional sparse reconstruction and sensor placement strategies face major…

Diffusion-based motion planners are becoming popular due to their well-established performance improvements, stemming from sample diversity and the ease of incorporating new constraints directly during inference. However, a primary…

Antibodies, crucial for immune defense, primarily rely on complementarity-determining regions (CDRs) to bind and neutralize antigens, such as viruses. The design of these CDRs determines the antibody's affinity and specificity towards its…

Quantitative Methods · Quantitative Biology 2024-09-10 Paulina Kulytė , Francisco Vargas , Simon Valentin Mathis , Yu Guang Wang , José Miguel Hernández-Lobato , Pietro Liò

Generative models on discrete state-spaces have a wide range of potential applications, particularly in the domain of natural sciences. In continuous state-spaces, controllable and flexible generation of samples with desired properties has…

Machine Learning · Computer Science 2025-03-27 Hunter Nisonoff , Junhao Xiong , Stephan Allenspach , Jennifer Listgarten

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Grasping is a fundamental skill in robotics with diverse applications across medical, industrial, and domestic domains. However, current approaches for predicting valid grasps are often tailored to specific grippers, limiting their…

Robotics · Computer Science 2024-10-25 Roman Freiberg , Alexander Qualmann , Ngo Anh Vien , Gerhard Neumann

3D scene generation is a core technology for gaming, film/VFX, and VR/AR. Growing demand for rapid iteration, high-fidelity detail, and accessible content creation has further increased interest in this area. Existing methods broadly follow…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Haozhi Zhu , Miaomiao Zhao , Dingyao Liu , Runze Tian , Yan Zhang , Jie Guo , Fenggen Yu

Diffusion models have emerged as a leading technique for generating images due to their ability to create high-resolution and realistic images. Despite their strong performance, diffusion models still struggle in managing image collections…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Hailong Yang , Te Zhang , Kup-sze Choi , Zhaohong Deng

Determining the optimal configuration of adsorbates on a slab (adslab) is pivotal in the exploration of novel catalysts across diverse applications. Traditionally, the quest for the lowest energy adslab configuration involves placing the…

Machine Learning · Computer Science 2024-05-08 Adeesh Kolluru , John R Kitchin

Diffusion models, emerging as powerful deep generative tools, excel in various applications. They operate through a two-steps process: introducing noise into training samples and then employing a model to convert random noise into new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Huijie Zhang , Yifu Lu , Ismail Alkhouri , Saiprasad Ravishankar , Dogyoon Song , Qing Qu

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Denoising diffusion models are a powerful type of generative models used to capture complex distributions of real-world signals. However, their applicability is limited to scenarios where training samples are readily available, which is not…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Ayush Tewari , Tianwei Yin , George Cazenavette , Semon Rezchikov , Joshua B. Tenenbaum , Frédo Durand , William T. Freeman , Vincent Sitzmann

This study presents a generative optimization framework that builds on a fine-tuned diffusion model and reward-directed sampling to generate high-performance engineering designs. The framework adopts a parametric representation of the…

Machine Learning · Computer Science 2025-08-05 Hadi Keramati , Patrick Kirchen , Mohammed Hannan , Rajeev K. Jaiman

Beamforming design for extremely large-scale multiple-input multiple-output (XL-MIMO) systems is challenging due to prohibitive computational complexity and complex near-field propagation effects. To address this, this paper introduces a…

Information Theory · Computer Science 2026-04-13 Xiyuan Liu , Qingqing Wu , Rui Wang , Qiaoyan Peng , Jun Wu

Macrocycles are ring-shaped molecules that offer a promising alternative to small-molecule drugs due to their enhanced selectivity and binding affinity against difficult targets. Despite their chemical value, they remain underexplored in…

Diffusion models have emerged as powerful generative models for graph generation, yet their use for conditional graph generation remains a fundamental challenge. In particular, guiding diffusion models on graphs under arbitrary reward…

Machine Learning · Computer Science 2025-05-27 Victor M. Tenorio , Nicolas Zilberstein , Santiago Segarra , Antonio G. Marques

Diffusion models (DMs) represent state-of-the-art generative models for continuous inputs. DMs work by constructing a Stochastic Differential Equation (SDE) in the input space (ie, position space), and using a neural network to reverse it.…

Machine Learning · Computer Science 2024-05-14 Tianrong Chen , Jiatao Gu , Laurent Dinh , Evangelos A. Theodorou , Joshua Susskind , Shuangfei Zhai
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