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Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

Computation and Language · Computer Science 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin

Drug development and pharmacovigilance are frequently bottlenecked by legacy clinical reporting pipelines. These monolithic systems encode regulatory-grade logic but resist AI integration by producing opaque output with no machine-readable…

Software Engineering · Computer Science 2026-05-15 Jaime Yan

Scientists have long sought to accurately predict outcomes of real-world events before they happen. Can AI systems do so more reliably? We study this question through clinical trial outcome prediction, a high-stakes open challenge even for…

Multi-Criteria Decision Making~(MCDM) is widely applied in various fields, using quantitative and qualitative analyses of multiple levels and attributes to support decision makers in making scientific and rational decisions in complex…

Artificial Intelligence · Computer Science 2025-02-25 Hui Wang , Fafa Zhang , Chaoxu Mu

The widespread adoption of cloud-based proprietary large language models (LLMs) has introduced significant challenges, including operational dependencies, privacy concerns, and the necessity of continuous internet connectivity. In this…

Machine Learning · Computer Science 2025-06-02 Chansung Park , Juyong Jiang , Fan Wang , Sayak Paul , Jing Tang

We present an open-source software pipeline to create patient-specific left atrial (LA) models with fibre orientations and a fibrosis map, suitable for electrophysiology simulations. The semi-automatic pipeline takes as input a contrast…

Large Language Models (LLMs) often provide chain-of-thought (CoT) reasoning traces that appear plausible, but may hide internal biases. We call these *unverbalized biases*. Monitoring models via their stated reasoning is therefore…

Machine Learning · Computer Science 2026-03-02 Iván Arcuschin , David Chanin , Adrià Garriga-Alonso , Oana-Maria Camburu

High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

Computation and Language · Computer Science 2025-10-17 Ziad Elshaer , Essam A. Rashed

Electronic medical records (EMRs), particularly in neurology, are inherently heterogeneous, sparse, and noisy, which poses significant challenges for large language models (LLMs) in clinical diagnosis. In such settings, single-agent systems…

Artificial Intelligence · Computer Science 2026-04-30 Shaowei Shen , Xiaohong Yang , Jie Yang , Lianfen Huang , Yongcai Zhang , Yang Zou , Seyyedali Hosseinalipour

Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

Computation and Language · Computer Science 2025-04-08 Juncheng Wu , Wenlong Deng , Xingxuan Li , Sheng Liu , Taomian Mi , Yifan Peng , Ziyang Xu , Yi Liu , Hyunjin Cho , Chang-In Choi , Yihan Cao , Hui Ren , Xiang Li , Xiaoxiao Li , Yuyin Zhou

In this paper, we introduce a clinical diagnosis template-based pipeline to systematically collect and structure pathological information. In collaboration with pathologists and guided by the the College of American Pathologists (CAP)…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Hao Lu , Ziniu Qian , Yifu Li , Yang Zhou , Bingzheng Wei , Yan Xu

Deploying a Machine Learning (ML) training pipeline into production requires good software engineering practices. Unfortunately, the typical data science workflow often leads to code that lacks critical software quality attributes. This…

The proliferation of complex structured data in hybrid sources, such as PDF documents and web pages, presents unique challenges for current Large Language Models (LLMs) and Multi-modal Large Language Models (MLLMs) in providing accurate…

Information Retrieval · Computer Science 2025-08-22 Shivani Upadhyay , Messiah Ataey , Syed Shariyar Murtaza , Yifan Nie , Jimmy Lin

Large language models (LLMs) are increasingly being applied to clinical care, a domain where both accuracy and transparent reasoning are critical for safe and trustworthy deployment. Chain-of-thought (CoT) prompting, which elicits…

Computation and Language · Computer Science 2025-12-09 Jiageng Wu , Kevin Xie , Bowen Gu , Nils Krüger , Kueiyu Joshua Lin , Jie Yang

Large language models (LLMs) are currently being used to answer medical questions across a variety of clinical domains. Recent top-performing commercial LLMs, in particular, are also capable of citing sources to support their responses. In…

Computation and Language · Computer Science 2024-02-06 Kevin Wu , Eric Wu , Ally Cassasola , Angela Zhang , Kevin Wei , Teresa Nguyen , Sith Riantawan , Patricia Shi Riantawan , Daniel E. Ho , James Zou

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

CI/CD pipeline failure management is time-consuming when performed manually. Automating this process is non-trivial because the information required for effective failure management is unstructured and cannot be automatically processed by…

Software Engineering · Computer Science 2026-02-09 Duong Bui , Stefan Grintz , Alexander Berndt , Thomas Bach

The advancement of vision-language models (VLMs) is hampered by a fragmented landscape of inconsistent and contaminated public datasets. We introduce FineVision, a meticulously collected, curated, and unified corpus of 24 million samples -…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Luis Wiedmann , Orr Zohar , Amir Mahla , Xiaohan Wang , Rui Li , Thibaud Frere , Leandro von Werra , Aritra Roy Gosthipaty , Andrés Marafioti

Despite advances in generative large language models (LLMs), practical application of specialized conversational AI agents remains constrained by computation costs, latency requirements, and the need for precise domain-specific relevance…

Computation and Language · Computer Science 2025-12-10 Eliot Brenner , Dominic Seyler , Manjunath Hegde , Andrei Simion , Koustuv Dasgupta , Bing Xiang