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In many practical data mining scenarios, such as network intrusion detection, Twitter spam detection, and computer-aided diagnosis, a source domain that is different from but related to a target domain is very common. In addition, a large…

Machine Learning · Computer Science 2021-08-24 Zhe Yuan , Yimin Wen

A new method called SurvLIME for explaining machine learning survival models is proposed. It can be viewed as an extension or modification of the well-known method LIME. The main idea behind the proposed method is to apply the Cox…

Machine Learning · Computer Science 2020-03-19 Maxim S. Kovalev , Lev V. Utkin , Ernest M. Kasimov

Typical cohorts in brain imaging studies are not large enough for systematic testing of all the information contained in the images. To build testable working hypotheses, investigators thus rely on analysis of previous work, sometimes…

We aim to create a framework for transfer learning using latent factor models to learn the dependence structure between a larger source dataset and a target dataset. The methodology is motivated by our goal of building a risk-assessment…

Machine Learning · Statistics 2016-12-05 Elizabeth C Lorenzi , Zhifei Sun , Erich Huang , Ricardo Henao , Katherine A Heller

Covariate shift and outcome model heterogeneity are two prominent challenges in leveraging external sources to improve risk modeling for underrepresented cohorts in paucity of accurate labels. We consider the transfer learning problem…

Methodology · Statistics 2024-10-10 Doudou Zhou , Mengyan Li , Tianxi Cai , Molei Liu

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

Methodology · Statistics 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

Time-to-event endpoints are frequently used as outcomes in oncology and other disease areas where the outcome of interest may not be observed within a predetermined period. Although many analytical methods address the challenges of…

Methodology · Statistics 2026-04-14 Chen-Yen Lin , Susan Halabi , Taehwa Choi

Collaborative filtering (CF) aims to predict users' ratings on items according to historical user-item preference data. In many real-world applications, preference data are usually sparse, which would make models overfit and fail to give…

Machine Learning · Computer Science 2012-10-29 Zhongqi Lu , Erheng Zhong , Lili Zhao , Wei Xiang , Weike Pan , Qiang Yang

Large language models (LLMs) achieve strong performance on plain text tasks but underperform on structured data like tables and databases. Potential challenges arise from their underexposure during pre-training and rigid text-to-structure…

Computation and Language · Computer Science 2025-07-28 Jiawei Gu , Ziting Xian , Yuanzhen Xie , Ye Liu , Enjie Liu , Ruichao Zhong , Mochi Gao , Yunzhi Tan , Bo Hu , Zang Li

This work presents the first large-scale neutral benchmark experiment focused on single-event, right-censored, low-dimensional survival data. Benchmark experiments are essential in methodological research to scientifically compare new and…

Machine Learning · Statistics 2026-04-24 Lukas Burk , John Zobolas , Bernd Bischl , Andreas Bender , Marvin N. Wright , Raphael Sonabend

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

An important task in clinical medicine is the construction of risk prediction models for specific subgroups of patients based on high-dimensional molecular measurements such as gene expression data. Major objectives in modeling…

Methodology · Statistics 2020-03-23 Katrin Madjar , Jörg Rahnenführer

We present a neural network framework for learning a survival model to predict a time-to-event outcome while simultaneously learning a topic model that reveals feature relationships. In particular, we model each subject as a distribution…

Machine Learning · Computer Science 2024-06-06 George H. Chen , Linhong Li , Ren Zuo , Amanda Coston , Jeremy C. Weiss

A prevalent feature of high-dimensional data is the dependence among covariates, and model selection is known to be challenging when covariates are highly correlated. To perform model selection for the high-dimensional Cox proportional…

Methodology · Statistics 2022-10-04 Pierre Bayle , Jianqing Fan

Predicting patient survival probabilities based on observed covariates is an important assessment in clinical practice. These patient-specific covariates are often measured over multiple follow-up appointments. It is then of interest to…

Methodology · Statistics 2021-11-11 Annabel L. Davies , Anthony C. C. Coolen , Tobias Galla

Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which…

Machine Learning · Computer Science 2023-04-27 Andre Vauvelle , Benjamin Wild , Aylin Cakiroglu , Roland Eils , Spiros Denaxas

Consider the problem of improving the estimation of conditional average treatment effects (CATE) for a target domain of interest by leveraging related information from a source domain with a different feature space. This heterogeneous…

Machine Learning · Computer Science 2022-10-13 Ioana Bica , Mihaela van der Schaar

The difference in restricted mean survival times between two groups is a clinically relevant summary measure. With observational data, there may be imbalances in confounding variables between the two groups. One approach to account for such…

Applications · Statistics 2014-10-17 Andrew Wey , David Vock , John Connett , Kyle Rudser

The Cox Proportional Hazards (PH) model is widely used in survival analysis. Recently, artificial neural network (ANN)-based Cox-PH models have been developed. However, training these Cox models with high-dimensional features typically…

Machine Learning · Computer Science 2026-01-29 Anchen Sun , Zhibin Chen , Xiaodong Cai

Survival analysis is essential for clinical decision-making, as it allows practitioners to estimate time-to-event outcomes, stratify patient risk profiles, and guide treatment planning. Deep learning has revolutionized this field with…

Machine Learning · Computer Science 2026-02-03 Pinar Erbil , Alberto Archetti , Eugenio Lomurno , Matteo Matteucci