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Chest X-ray (CXR) imaging is one of the most widely used diagnostic modalities in clinical practice, encompassing a broad spectrum of diagnostic tasks. Recent advancements have seen the extensive application of reasoning-based multimodal…

Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinquan Guan , Qi Chen , Lizhou Liang , Yuhang Liu , Vu Minh Hieu Phan , Minh-Son To , Jian Chen , Yutong Xie

Recent progress in Large Vision-Language Models (LVLMs) has enabled promising applications in medical tasks, such as report generation and visual question answering. However, existing benchmarks focus mainly on the final diagnostic answer,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hyungyung Lee , Geon Choi , Jung-Oh Lee , Hangyul Yoon , Hyuk Gi Hong , Edward Choi

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in…

Artificial Intelligence · Computer Science 2025-05-22 Ziqing Fan , Cheng Liang , Chaoyi Wu , Ya Zhang , Yanfeng Wang , Weidi Xie

The rapid evolution of artificial intelligence, especially in large language models (LLMs), has significantly impacted various domains, including healthcare. In chest X-ray (CXR) analysis, previous studies have employed LLMs, but with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Jonggwon Park , Soobum Kim , Byungmu Yoon , Jihun Hyun , Kyoyun Choi

Despite significant progress in Multi-modal Large Language Models (MLLMs), their clinical reasoning capacity for multi-modal diagnosis remains largely unexamined. Current benchmarks, mostly single-modality data, can't evaluate progressive…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Gui Wang , Zehao Zhong , YongSong Zhou , Yudong Li , Ende Wu , Wooi Ping Cheah , Rong Qu , Jianfeng Ren , Linlin Shen

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

Chest X-rays (CXRs) are among the most frequently performed imaging examinations worldwide, yet rising imaging volumes increase radiologist workload and the risk of diagnostic errors. Although artificial intelligence (AI) systems have shown…

Vision-language models (VLMs) are increasingly used for medical image interpretation, yet they frequently hallucinate, generating clinically plausible but factually incorrect findings that pose direct patient safety risks. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Haoyu Wang , Zitong Li

Significant methodological strides have been made toward Chest X-ray (CXR) understanding via modern vision-language models (VLMs), demonstrating impressive Visual Question Answering (VQA) and CXR report generation abilities. However,…

Artificial Intelligence · Computer Science 2024-04-01 Seil Kang , Donghyun Kim , Junhyeok Kim , Hyo Kyung Lee , Seong Jae Hwang

Recent vision-language models (VLMs) have shown strong generalization and multimodal reasoning abilities in natural domains. However, their application to medical diagnosis remains limited by the lack of comprehensive and structured…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Sheng Lu , Hao Chen , Rui Yin , Juyan Ba , Yu Zhang , Yuanzhe Li

Large Vision Language Models (LVLMs) show promise in medical applications, but their inability to faithfully ground responses in visual evidence raises serious concerns about clinical trustworthiness. While visual attribution methods are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Guangzhi Xiong , Qiao Jin , Sanchit Sinha , Zhiyong Lu , Aidong Zhang

Vision-language models have proven to be of great benefit for medical image analysis since they learn rich semantics from both images and reports. Prior efforts have focused on better alignment of image and text representations to enhance…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Yixiong Chen , Shawn Xu , Andrew Sellergren , Yossi Matias , Avinatan Hassidim , Shravya Shetty , Daniel Golden , Alan Yuille , Lin Yang

Chest X-ray imaging is crucial for diagnosing pulmonary and cardiac diseases, yet its interpretation demands extensive clinical experience and suffers from inter-observer variability. While deep learning models offer high diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Chee Ng , Liliang Sun , Shaoqing Tang

Automated interpretation of chest X-rays (CXR) is a critical task with the potential to significantly improve clinical workflow and patient care. While recent advances in multimodal foundation models have shown promise, effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Alexander Davis , Rafael Souza , Jia-Hao Lim

Chest radiograph interpretation requires temporal reasoning over prior and current studies, yet most vision-language models are trained on static image-report pairs and lack explicit supervision for modeling longitudinal change. We…

Chest X-ray interpretation is one of the most frequently performed diagnostic tasks in medicine and a primary target for AI development, yet current vision-language models are primarily trained on datasets of paired images and reports, not…

Chest X-rays (CXRs) are the most frequently performed imaging examinations in clinical settings. Recent advancements in Large Multimodal Models (LMMs) have enabled automated CXR interpretation, enhancing diagnostic accuracy and efficiency.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Qingqiu Li , Zihang Cui , Seongsu Bae , Jilan Xu , Runtian Yuan , Yuejie Zhang , Rui Feng , Quanli Shen , Xiaobo Zhang , Junjun He , Shujun Wang
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