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Motivated by multi-center biomedical studies that cannot share individual data due to privacy and ownership concerns, we develop communication-efficient iterative distributed algorithms for estimation and inference in the high-dimensional…

Methodology · Statistics 2024-06-25 Pierre Bayle , Jianqing Fan , Zhipeng Lou

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a novel weighting strategy to account for time-varying…

Methodology · Statistics 2023-08-08 Liangyuan Hu , Jiayi Ji , Himanshu Joshi , Erick Scott , Fan Li

Functional data analysis has been extensively conducted. In this study, we consider a partially functional model, under which some covariates are scalars and have linear effects, while some other variables are functional and have…

Methodology · Statistics 2023-01-11 Weijuan Liang , Qingzhao Zhang , Shuangge Ma

This paper considers the empirical likelihood (EL) construction of confidence intervals for a linear functional based on right censored lifetime data. Many of the results in literature show that log EL has a limiting scaled chi-square…

Statistics Theory · Mathematics 2012-03-28 Shuyuan He , Wei Liang , Junshan Shen , Grace Yang

Accelerated failure time (AFT) models provide a direct and interpretable time-scale description of covariate effects in lifetime data analysis, but classical formulations rely on linear predictors and are therefore limited in their ability…

Machine Learning · Statistics 2026-03-20 Mebin Jose , Jisha Francis , Sudheesh Kumar Kattumannil

The advent of wearable and sensor technologies now leads to functional predictors which are intrinsically infinite dimensional. While the existing approaches for functional data and survival outcomes lean on the well-established Cox model,…

Methodology · Statistics 2024-07-01 Rahul Ghosal , Marcos Matabuena , Sujit K. Ghosh

The problem of how to best select variables for confounding adjustment forms one of the key challenges in the evaluation of exposure effects in observational studies, and has been the subject of vigorous recent activity in causal inference.…

Methodology · Statistics 2021-12-02 Kelly Van Lancker , Oliver Dukes , Stijn Vansteelandt

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

Methodology · Statistics 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

This paper presents a unified rank-based inferential procedure for fitting the accelerated failure time model to partially interval-censored data. A Gehan-type monotone estimating function is constructed based on the idea of the familiar…

Methodology · Statistics 2026-04-14 Taehwa Choi , Sangbum Choi , Dipankar Bandyopadhyay

It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

Methodology · Statistics 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

Survival data with time-varying covariates are common in practice. If relevant, they can improve on the estimation of survival function. However, the traditional survival forests - conditional inference forest, relative risk forest and…

Applications · Statistics 2022-06-06 Weichi Yao , Halina Frydman , Denis Larocque , Jeffrey S. Simonoff

Imputation is a popular approach to handling censored, missing, and error-prone covariates -- all coarsened data types for which the true values are unknown. However, there are nuances to imputing these different data types based on the…

Methodology · Statistics 2025-04-29 Sarah C. Lotspeich , Ethan M. Alt

Interval censoring occurs when event times are only known to fall between scheduled assessments, a common design in clinical trials, epidemiology, and reliability studies. Standard right-censoring methods, such as Kaplan-Meier and Cox…

Methodology · Statistics 2025-09-04 J. T. Korley

In many applications, the variables that characterize a stochastic system are measured along a second dimension, such as time. This results in multivariate functional data and the interest is in describing the statistical dependences among…

Methodology · Statistics 2025-11-11 Marco Borriero , Luigi Augugliaro , Gianluca Sottile , Veronica Vinciotti

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative…

Statistics Theory · Mathematics 2025-03-19 Ilias Willems , Sara Rutten , Gilles Crommen , Ingrid Van Keilegom

In survival analysis, estimating the conditional survival function given predictors is often of interest. There is a growing trend in the development of deep learning methods for analyzing censored time-to-event data, especially when…

Machine Learning · Statistics 2025-03-13 Sehwan Kim , Rui Wang , Wenbin Lu

Truncation is a statistical phenomenon that occurs in many time to event studies. For example, autopsy-confirmed studies of neurodegenerative diseases are subject to an inherent left and right truncation, also known as double truncation.…

Methodology · Statistics 2018-03-28 Lior Rennert , Sharon X. Xie

This article addresses the problem of functional supervised classification of Cox process trajectories, whose random intensity is driven by some exogenous random covariable. The classification task is achieved through a regularized convex…

Statistics Theory · Mathematics 2014-10-16 Gérard Biau , Benoît Cadre , Quentin Paris

This paper addresses estimation in a longitudinal regression model for association between a scalar outcome and a set of longitudinally-collected functional covariates or predictor curves. The framework consists of estimating a time-varying…

Applications · Statistics 2020-06-30 Madan G. Kundu , Jaroslaw Harezlak , Timothy W. Randolph

Cox models with time-dependent coefficients and covariates are widely used in survival analysis. In high-dimensional settings, sparse regularization techniques are employed for variable selection, but existing methods for time-dependent Cox…