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Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering:…

Applications · Statistics 2010-12-21 Kyung In Kim , Etienne Roquain , Mark Van De Wiel

Imaging mass spectrometry (IMS) has transformed proteomics by providing an avenue for collecting spatially distributed molecular data. Mass spectrometry data acquired with matrix assisted laser desorption ionization (MALDI) IMS consist of…

Applications · Statistics 2016-02-05 Lyron J. Winderbaum , Inge Koch , Ove J. R. Gustafsson , Stephan Meding , Peter Hoffmann

Multifractal analysis (MFA) provides a framework for the global characterization of image textures by describing the spatial fluctuations of their local regularity based on the multifractal spectrum. Several works have shown the interest of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Kareth M. León-López , Abderrahim Halimi , Jean-Yves Tourneret , Herwig Wendt

Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate approaches that lead to information waste.…

Methodology · Statistics 2025-11-18 Yuan Zhong , Gang Chen , Paul A. Taylor , Jian Kang

We discuss topological aspects of cluster analysis and show that inferring the topological structure of a dataset before clustering it can considerably enhance cluster detection: theoretical arguments and empirical evidence show that…

Machine Learning · Computer Science 2022-07-04 Moritz Herrmann , Daniyal Kazempour , Fabian Scheipl , Peer Kröger

In semantic segmentation, the accuracy of models heavily depends on the high-quality annotations. However, in many practical scenarios, such as medical imaging and remote sensing, obtaining true annotations is not straightforward and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Ryu Tadokoro , Tsukasa Takagi , Shin-ichi Maeda

Clustering is a fundamental unsupervised representation learning task with wide application in computer vision and pattern recognition. Deep clustering utilizes deep neural networks to learn latent representation, which is suitable for…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Wenhao Wu , Weiwei Wang , Shengjiang Kong

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

In this paper, we present a deep extension of Sparse Subspace Clustering, termed Deep Sparse Subspace Clustering (DSSC). Regularized by the unit sphere distribution assumption for the learned deep features, DSSC can infer a new data…

Computer Vision and Pattern Recognition · Computer Science 2017-09-26 Xi Peng , Jiashi Feng , Shijie Xiao , Jiwen Lu , Zhang Yi , Shuicheng Yan

Geographic Information Systems (GIS) and related technologies have generated substantial interest among statisticians with regard to scalable methodologies for analyzing large spatial datasets. A variety of scalable spatial process models…

Machine Learning · Statistics 2021-09-10 Sudipto Banerjee

A wide range of Bayesian models have been proposed for data that is divided hierarchically into groups. These models aim to cluster the data at different levels of grouping, by assigning a mixture component to each datapoint, and a mixture…

Machine Learning · Computer Science 2015-04-21 Adway Mitra

Magnetic resonance imaging (MRI) plays a vital role in the scientific investigation and clinical management of multiple sclerosis. Analyses of binary multiple sclerosis lesion maps are typically "mass univariate" and conducted with standard…

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Spatial transcriptomics (ST) provides essential spatial context by mapping gene expression within tissue, enabling detailed study of cellular heterogeneity and tissue organization. However, aligning ST data with histology images poses…

Subspace clustering refers to the task of finding a multi-subspace representation that best fits a collection of points taken from a high-dimensional space. This paper introduces an algorithm inspired by sparse subspace clustering (SSC) [In…

Machine Learning · Computer Science 2014-05-26 Mahdi Soltanolkotabi , Ehsan Elhamifar , Emmanuel J. Candès

Spatial statistical models are commonly used in geographical scenarios to ensure spatial variation is captured effectively. However, spatial models and cluster algorithms can be complicated and expensive. This paper pursues three main…

Subspace clustering methods which embrace a self-expressive model that represents each data point as a linear combination of other data points in the dataset provide powerful unsupervised learning techniques. However, when dealing with…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Katsuya Hotta , Takuya Akashi , Shogo Tokai , Chao Zhang

We consider the problem of analyzing multivariate time series collected on multiple subjects, with the goal of identifying groups of subjects exhibiting similar trends in their recorded measurements over time as well as time-varying groups…

In order to perform complex actions in human environments, an autonomous robot needs the ability to understand the environment, that is, to gather and maintain spatial knowledge. Topological map is commonly used for representing large…

Robotics · Computer Science 2017-07-11 Kaiyu Zheng