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As single-cell RNA sequencing datasets grow in adoption, scale, and complexity, data analysis remains a bottleneck for many research groups. Although frontier AI agents have improved dramatically at software engineering and general data…

Genomics · Quantitative Biology 2026-02-11 Kenny Workman , Zhen Yang , Harihara Muralidharan , Aidan Abdulali , Hannah Le

GPU kernel optimization is increasingly critical for efficient deep learning systems, but writing high-performance kernels still requires substantial low-level expertise. Recent AI coding agents can iteratively read code, invoke compilers…

Existing AI benchmarks for software automation rarely combine cross-application coordination, autonomous API discovery, and policy adherence. Real business workflows demand all three: a single task may span a CRM, inbox, calendar, and…

Artificial Intelligence · Computer Science 2026-04-22 Daniel Shepard , Robin Salimans

Software engineering (SE) is increasingly collaborative, with developers working together on shared complex codebases. Effective collaboration in shared environments requires participants -- whether humans or AI agents -- to stay on the…

Software Engineering · Computer Science 2025-06-10 Xuehang Guo , Xingyao Wang , Yangyi Chen , Sha Li , Chi Han , Manling Li , Heng Ji

The rise of agentic AI is reshaping software engineering in two intertwined directions: agents are increasingly applied to support software engineering tasks, and Agentic AI systems themselves are complex systems that require re-thinking…

AI agents are increasingly deployed in multi-tenant cloud environments, where they execute diverse tool calls within sandboxed containers, each call with distinct resource demands and rapid fluctuations. We present a systematic…

Operating Systems · Computer Science 2026-02-24 Yusheng Zheng , Jiakun Fan , Quanzhi Fu , Yiwei Yang , Wei Zhang , Andi Quinn

Practitioners are increasingly turning to Extract-Load-Transform (ELT) pipelines with the widespread adoption of cloud data warehouses. However, designing these pipelines often involves significant manual work to ensure correctness. Recent…

Databases · Computer Science 2025-04-16 Tengjun Jin , Yuxuan Zhu , Daniel Kang

Large language model agents increasingly operate through environment-facing scaffolds that expose files, web pages, APIs, and logs. These observations influence tool use, state tracking, and action sequencing, yet their reliability and…

Artificial Intelligence · Computer Science 2026-05-13 Strick Sheng , Ziyue Wang , Liyi Zhou

AI coding agents are increasingly used to write real-world software, but ensuring that their outputs are correct remains a fundamental challenge. Formal verification offers a promising path: an agent generates code together with a…

Although LLM-based agents have attracted significant attention in domains such as software engineering and machine learning research, their role in advancing combinatorial optimization (CO) remains relatively underexplored. This gap…

Computation and Language · Computer Science 2025-08-25 Weiwei Sun , Shengyu Feng , Shanda Li , Yiming Yang

As software systems grow in scale and complexity, vulnerability management is increasingly strained by high alert volumes, fragmented toolchains, and manual triage processes. We introduce AgenticVM, a multi-agent framework that integrates…

Cryptography and Security · Computer Science 2026-05-05 Asrul Arifin , Hussain Ahmad , Yiyao Zhang , Diksha Goel

Agents based on Large Language Models (LLMs) have shown promise for performing sophisticated software engineering tasks autonomously. In addition, there has been progress towards developing agents that can perform parts of the research…

Computation and Language · Computer Science 2026-04-23 Nicholas Edwards , Yukyung Lee , Yujun Audrey Mao , Yulu Qin , Sebastian Schuster , Najoung Kim

The growth of Large Language Model (LLM) technology has raised expectations for automated coding. However, software engineering is more than coding and is concerned with activities including maintenance and evolution of a project. In this…

Software Engineering · Computer Science 2025-12-09 Leonhard Applis , Yuntong Zhang , Shanchao Liang , Nan Jiang , Lin Tan , Abhik Roychoudhury

Large language models (LLMs) show remarkable potential to act as computer agents, enhancing human productivity and software accessibility in multi-modal tasks that require planning and reasoning. However, measuring agent performance in…

AI agents have become surprisingly proficient at software engineering over the past year, largely due to improvements in reasoning capabilities. This raises a deeper question: can these systems extend their capabilities to automate AI…

Software Engineering · Computer Science 2026-03-11 Ben Rank , Hardik Bhatnagar , Ameya Prabhu , Shira Eisenberg , Karina Nguyen , Matthias Bethge , Maksym Andriushchenko

Architectural code smells erode software maintainability and are costly to repair manually, yet unlike localized bugs, they require cross-module reasoning about design intent that challenges both developers and automated tools. While large…

Software Engineering · Computer Science 2026-05-13 Ion George Dinu , Marian Cristian Mihăescu , Traian Rebedea

Large language models (LLMs) have shown growing potential in software engineering, yet few benchmarks evaluate their ability to repair software during migration across instruction set architectures (ISAs). Cross-ISA migration, such as…

The Agentic Paradigm faces a significant Software Engineering Absence, yielding Agentic systems commonly lacking robustness, observability, and evolvability. To address these deficiencies, we propose a principled engineering framework…

Artificial Intelligence · Computer Science 2025-12-02 Jiazheng Sun , Ruimeng Yang , Xu Han , Jiayang Niu , Mingxuan Li , Te Yang , Yongyong Lu , Xin Peng

As Large Language Models (LLMs) advance toward embodied AI agents operating in physical environments, a fundamental question emerges: can models trained on text corpora reliably reason about complex physics while adhering to safety…

Artificial Intelligence · Computer Science 2026-04-13 Yalun Wu , Haotian Liu , Zhoujun Li , Boyang Wang

We present an approach to software testing automation using Agentic Retrieval-Augmented Generation (RAG) systems for Quality Engineering (QE) artifact creation. We combine autonomous AI agents with hybrid vector-graph knowledge systems to…

Software Engineering · Computer Science 2025-10-14 Mohanakrishnan Hariharan , Satish Arvapalli , Seshu Barma , Evangeline Sheela