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Reliable epidemiological reasoning requires synthesizing study evidence to infer disease burden, transmission dynamics, and intervention effects at the population level. Existing medical question answering benchmarks primarily emphasize…

Computation and Language · Computer Science 2026-05-27 Mingyang Wei , Dehai Min , Zewen Liu , Yuzhang Xie , Guanchen Wu , Ziyang Zhang , Carl Yang , Max S. Y. Lau , Qi He , Lu Cheng , Wei Jin

Despite recent advances in the accuracy of brain tumor segmentation, the results still suffer from low reliability and robustness. Uncertainty estimation is an efficient solution to this problem, as it provides a measure of confidence in…

Image and Video Processing · Electrical Eng. & Systems 2022-08-15 Hao Li , Yang Nan , Javier Del Ser , Guang Yang

Medical imaging provides critical evidence for clinical diagnosis, treatment planning, and surgical decisions, yet most existing imaging models are narrowly focused and require multiple specialized networks, limiting their generalization.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Guoxin Wang , Jun Zhao , Xinyi Liu , Yanbo Liu , Xuyang Cao , Chao Li , Zhuoyun Liu , Qintian Sun , Fangru Zhou , Haoqiang Xing , Zhenhong Yang

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Unsupervised classification is a fundamental machine learning problem. Real-world data often contain imperfections, characterized by uncertainty and imprecision, which are not well handled by traditional methods. Evidential clustering,…

Machine Learning · Computer Science 2025-08-08 Victor F. Lopes de Souza , Karima Bakhti , Sofiane Ramdani , Denis Mottet , Abdelhak Imoussaten

Interpretable deep learning models have received widespread attention in the field of image recognition. Due to the unique multi-instance learning of medical images and the difficulty in identifying decision-making regions, many…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yitao Peng , Lianghua He , Die Hu , Yihang Liu , Longzhen Yang , Shaohua Shang

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Referring object detection and referring image segmentation are important tasks that require joint understanding of visual information and natural language. Yet there has been evidence that current benchmark datasets suffer from bias, and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Runtao Liu , Chenxi Liu , Yutong Bai , Alan Yuille

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Reasoning is a hallmark of human intelligence, enabling adaptive decision-making in complex and unfamiliar scenarios. In contrast, machine intelligence remains bound to training data, lacking the ability to dynamically refine solutions at…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Shaheer U. Saeed , Yipei Wang , Veeru Kasivisvanathan , Brian R. Davidson , Matthew J. Clarkson , Yipeng Hu , Daniel C. Alexander

When building artificial intelligence systems that can reason and answer questions about visual data, we need diagnostic tests to analyze our progress and discover shortcomings. Existing benchmarks for visual question answering can help,…

Computer Vision and Pattern Recognition · Computer Science 2016-12-22 Justin Johnson , Bharath Hariharan , Laurens van der Maaten , Li Fei-Fei , C. Lawrence Zitnick , Ross Girshick

Abstruse learning algorithms and complex datasets increasingly characterize modern clinical decision support systems (CDSS). As a result, clinicians cannot easily or rapidly scrutinize the CDSS recommendation when facing a difficult…

Artificial Intelligence · Computer Science 2021-11-02 Bojian Hou , Hao Zhang , Gur Ladizhinsky , Gur Ladizhinsky , Stephen Yang , Volodymyr Kuleshov , Fei Wang , Qian Yang

Parameter-efficient adaptation of vision-language foundation models is crucial for precise multimodal understanding of biomedical images, yet existing methods remain deterministic and often struggle under domain shift or ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Taha Koleilat , Hassan Rivaz , Yiming Xiao

The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable…

Computation and Language · Computer Science 2025-05-30 Yakun Zhu , Zhongzhen Huang , Linjie Mu , Yutong Huang , Wei Nie , Jiaji Liu , Shaoting Zhang , Pengfei Liu , Xiaofan Zhang

Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger

Despite the remarkable progress of Vision-Language Models (VLMs) in adopting "Thinking-with-Images" capabilities, accurately evaluating the authenticity of their reasoning process remains a critical challenge. Existing benchmarks mainly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Xuchen Li , Xuzhao Li , Renjie Pi , Shiyu Hu , Jian Zhao , Jiahui Gao

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

The high complexity of deep learning models is associated with the difficulty of explaining what evidence they recognize as correlating with specific disease labels. This information is critical for building trust in models and finding…

Image and Video Processing · Electrical Eng. & Systems 2023-04-21 Ricardo Bigolin Lanfredi , Joyce D. Schroeder , Clement Vachet , Tolga Tasdizen