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Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

In this paper, we develop a novel logic-based approach to detecting high-level temporally extended events from timestamped data and background knowledge. Our framework employs logical rules to capture existence and termination conditions…

Artificial Intelligence · Computer Science 2026-04-24 Yvon K. Awuklu , Meghyn Bienvenu , Katsumi Inoue , Vianney Jouhet , Fleur Mougin

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured…

Computation and Language · Computer Science 2026-04-21 Arya Hadizadeh Moghaddam , Drew Ross , Mohsen Nayebi Kerdabadi , Dongjie Wang , Zijun Yao

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

Machine Learning · Computer Science 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Clinical language models have achieved strong performance on downstream tasks by pretraining on domain specific corpora such as discharge summaries and medical notes. However, most approaches treat the electronic health record as a static…

Computation and Language · Computer Science 2025-04-28 Tatsunori Tanaka , Fi Zheng , Kai Sato , Zhifeng Li , Yuanyun Zhang , Shi Li

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…

Clinical notes contain rich patient information, such as diagnoses or medications, making them valuable for patient representation learning. Recent advances in large language models have further improved the ability to extract meaningful…

Machine Learning · Computer Science 2025-09-23 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Rich Electronic Health Records (EHR), have created opportunities to improve clinical processes using machine learning methods. Prediction of the same patient events at different time horizons can have very different applications and…

Machine Learning · Computer Science 2023-03-07 Hao Liu , Muhan Zhang , Zehao Dong , Lecheng Kong , Yixin Chen , Bradley Fritz , Dacheng Tao , Christopher King

Electronic health record (EHR) data is sparse and irregular as it is recorded at irregular time intervals, and different clinical variables are measured at each observation point. In this work, we propose a multi-view features integration…

Machine Learning · Computer Science 2021-01-27 Yurim Lee , Eunji Jun , Heung-Il Suk

Predicting future clinical events from longitudinal electronic health records (EHRs) requires selecting plausible outcomes from a large and structured event space under sparse observations. While clinical coding systems provide hierarchical…

Machine Learning · Computer Science 2026-05-08 Zhan Qu , Michael Färber

Accurate clinical prognosis requires synthesizing structured Electronic Health Records (EHRs) with real-time physiological signals like the Electrocardiogram (ECG). Large Language Models (LLMs) offer a powerful reasoning engine for this…

Machine Learning · Computer Science 2026-01-27 Jialu Tang , Tong Xia , Yuan Lu , Aaqib Saeed

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Forecasting how a patient's condition is likely to evolve, including possible deterioration, recovery, treatment needs, and care transitions, could support more proactive and personalized care, but requires modeling heterogeneous and…

Machine Learning · Computer Science 2026-03-26 Chantal Pellegrini , Ege Özsoy , David Bani-Harouni , Matthias Keicher , Nassir Navab

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

Large language models (LLMs) can generate fluent clinical summaries of remote therapeutic monitoring time series. However, it remains unclear whether these narratives faithfully capture clinically significant events, such as sustained…

Artificial Intelligence · Computer Science 2026-03-03 Aditya Shukla , Yining Yuan , Ben Tamo , Yifei Wang , Micky Nnamdi , Shaun Tan , Jieru Li , Benoit Marteau , Brad Willingham , May Wang

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Medical time series has been playing a vital role in real-world healthcare systems as valuable information in monitoring health conditions of patients. Accurate classification for medical time series, e.g., Electrocardiography (ECG)…

Machine Learning · Computer Science 2025-02-10 Wei Fan , Jingru Fei , Dingyu Guo , Kun Yi , Xiaozhuang Song , Haolong Xiang , Hangting Ye , Min Li