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Large language models (LLMs) have demonstrated remarkable capabilities in tasks requiring reasoning and multi-step problem-solving through the use of chain-of-thought (CoT) prompting. However, generating the full CoT process results in…
Recent large language models support inputs of up to 10 million tokens, yet they perform poorly on long-context tasks that require complex reasoning. Such tasks can be solved using only a subset of the input -- a proxy context -- rather…
Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…
Societies worldwide are rapidly entering a super-aged era, making elderly health a pressing concern. The aging population is increasing the burden on national economies and households. Dementia cases are rising significantly with this…
Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical…
Chain-of-Thought (CoT) reasoning has emerged as a key technique for eliciting complex reasoning in Large Language Models (LLMs). Although interpretable, its dependence on natural language limits the model's expressive bandwidth. Continuous…
Chain-of-Thought (CoT) has been shown to significantly improve the reasoning accuracy of large language models (LLMs) on complex tasks. However, due to the autoregressive, step-by-step generation paradigm, existing CoT methods suffer from…
Chain-of-Thought (CoT) is widely applied to enhance the LLM capability in math, coding and reasoning tasks. However, its performance is limited for open-domain tasks, when there are no clearly defined reasoning steps or logical transitions.…
Chain-of-Thought (CoT) technique has proven effective in improving the performance of large language models (LLMs) on complex reasoning tasks. However, the performance gains are inconsistent across different tasks, and the underlying…
Chain-of-thought and more broadly test-time compute are known to augment the expressive capabilities of language models and have led to major innovations in reasoning. Motivated by this success, this paper explores latent chain-of-thought…
The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…
Accurate clinical prognosis requires synthesizing structured Electronic Health Records (EHRs) with real-time physiological signals like the Electrocardiogram (ECG). Large Language Models (LLMs) offer a powerful reasoning engine for this…
Large language models (LLMs) achieve strong reasoning performance through chain-of-thought (CoT) reasoning, yet often generate unnecessarily long reasoning paths that incur high inference cost. Recent self-consistency-based approaches…
Current clinical agent built on small LLMs, such as TxAgent suffer from a \textit{Context Utilization Failure}, where models successfully retrieve biomedical evidence due to supervised finetuning but fail to ground their diagnosis in that…
In information retrieval, large language models (LLMs) have demonstrated remarkable potential in text reranking tasks by leveraging their sophisticated natural language understanding and advanced reasoning capabilities. However,…
Chain-of-thought (CoT) reasoning is fundamental to modern LLM architectures and represents a critical intervention point for AI safety. However, CoT reasoning may exhibit failure modes that we note as pathologies, which prevent it from…
Large language models (LLMs) excel at complex reasoning but can still exhibit harmful behaviors. Current alignment strategies typically embed safety into model weights, making these controls implicit, static, and difficult to modify. This…
Chain-of-Thought (CoT) prompting plays an indispensable role in endowing large language models (LLMs) with complex reasoning capabilities. However, CoT currently faces two fundamental challenges: (1) Sufficiency, which ensures that the…
Long chain-of-thought (CoT) is an essential ingredient in effective usage of modern large language models, but our understanding of the reasoning strategies underlying these capabilities remains limited. While some prior works have…
Accurate tumor analysis is central to clinical radiology and precision oncology, where early detection, reliable lesion characterization, and pathology-level risk assessment guide diagnosis and treatment planning. Chain-of-Thought (CoT)…