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A key feature of many developmental systems is their ability to self-organize spatial patterns of functionally distinct cell fates. To ensure proper biological function, such patterns must be established reproducibly, by controlling and…

Biological Physics · Physics 2023-12-20 David B. Brückner , Gašper Tkačik

Self-organization is a fundamental process of complex biological systems, particularly during the early stages of development. In the mammalian embryo, blastocyst formation exemplifies a self-organized system, involving the correct…

Quantitative Methods · Quantitative Biology 2025-05-30 Michael A. Ramirez-Sierra , Thomas R. Sokolowski

"Self-organization" has become a watchword in developmental biology, characterizing observations in which embryonic or induced stem cells of animals replicate morphological steps and outcomes seen in intact embryos. While the term was…

Tissues and Organs · Quantitative Biology 2021-11-24 Stuart A. Newman

Self-organization is ubiquitous in nature and mind. However, machine learning and theories of cognition still barely touch the subject. The hurdle is that general patterns are difficult to define in terms of dynamical equations and…

Artificial Intelligence · Computer Science 2023-02-07 Danilo Vasconcellos Vargas , Tham Yik Foong , Heng Zhang

Self-organisation lies at the core of fundamental but still unresolved scientific questions, and holds the promise of de-centralised paradigms crucial for future technological developments. While self-organising processes have been…

Adaptation and Self-Organizing Systems · Physics 2019-04-16 Fernando Rosas , Pedro A. M. Mediano , Martin Ugarte , Henrik J. Jensen

From flocking birds to schooling fish, organisms interact to form collective dynamics across the natural world. Self-organization is present at smaller scales as well: cells interact and move during development to produce patterns in fish…

Quantitative Methods · Quantitative Biology 2024-07-16 Alexandria Volkening

As a result of a hundred million years of evolution, living animals have adapted extremely well to their ecological niche. Such adaptation implies species-specific interactions with their immediate environment by processing sensory cues and…

Disordered Systems and Neural Networks · Physics 2022-04-28 Tom Birkoben , Hermann Kohlstedt

The idea is advanced that self-organization in complex systems can be treated as decision making (as it is performed by humans) and, vice versa, decision making is nothing but a kind of self-organization in the decision maker nervous…

Adaptation and Self-Organizing Systems · Physics 2014-08-08 V. I. Yukalov , D. Sornette

Pretraining on large, semantically rich datasets is key for developing language models. Surprisingly, recent studies have shown that even synthetic data, generated procedurally through simple semantic-free algorithms, can yield some of the…

Machine Learning · Computer Science 2025-05-29 Zachary Shinnick , Liangze Jiang , Hemanth Saratchandran , Anton van den Hengel , Damien Teney

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Dynamic patterning of specific proteins is essential for the spatiotemporal regulation of many important intracellular processes in procaryotes, eucaryotes, and multicellular organisms. The emergence of patterns generated by interactions of…

Biological Physics · Physics 2018-05-11 Jacob Halatek , Fridtjof Brauns , Erwin Frey

We study open-ended evolution by focusing on computational and information-processing dynamics underlying major evolutionary transitions. In doing so, we consider biological organisms as hierarchical dynamical systems that generate…

We examine the evolution of expression patterns and the organization of genetic information in populations of self-replicating digital organisms. Seeding the experiments with a linearly expressed ancestor, we witness the development of…

adap-org · Physics 2007-05-23 Charles Ofria , Christoph Adami

Humans learn complex latent structures from their environments (e.g., natural language, mathematics, music, social hierarchies). In cognitive science and cognitive neuroscience, models that infer higher-order structures from sensory or…

Artificial Intelligence · Computer Science 2018-10-03 Andrea E. Martin , Leonidas A. A. Doumas

In this paper it is shown how to map a data manifold into a simpler form by progressively discarding small degrees of freedom. This is the key to self-organising data fusion, where the raw data is embedded in a very high-dimensional space…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Stephen Luttrell

Humans can make predictions on various time scales and hierarchical levels. Thereby, the learning of event encodings seems to play a crucial role. In this work we model the development of hierarchical predictions via autonomously learned…

Machine Learning · Computer Science 2022-08-30 Christian Gumbsch , Maurits Adam , Birgit Elsner , Georg Martius , Martin V. Butz

A big challenge in current biology is to understand the exact self-organization mechanism underlying complex multi-physics coupling developmental processes. With multiscale computations of from subcellular gene expressions to cell…

Cell Behavior · Quantitative Biology 2021-05-18 Xiaoliang Wang , Dongyun Bai

Self-organization is the autonomous assembly of a network of interacting components into a stable, organized pattern. This article shows that the process of self-assembly can be encoded in terms of evolutionary entropy, a statistical…

Statistical Mechanics · Physics 2023-05-29 Lloyd A. Demetrius

Disordered systems subject to a fluctuating environment can self-organize into a complex history-dependent response, retaining a memory of the driving. In sheared amorphous solids, self-organization is established by the emergence of a…

Soft Condensed Matter · Physics 2026-01-08 Muhittin Mungan , Eric Clement , Damien Vandembroucq , Srikanth Sastry

We explain how hierarchical organization of biological systems emerges naturally during evolution, through a transition in the units of individuality. We will show how these transitions are the result of competing selective forces operating…

Populations and Evolution · Quantitative Biology 2015-06-16 Cameron Smith , Matthieu Laneuville , Nicholas Guttenberg
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